{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:38:05Z","timestamp":1790617085822,"version":"4.1.0"},"reference-count":34,"publisher":"The Royal Society","issue":"1767","license":[{"start":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T00:00:00Z","timestamp":1547424000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"funder":[{"name":"the Strategic Priority Research Program of the Chinese Academy of Sciences","award":["No. XDB11040200"],"award-info":[{"award-number":["No. XDB11040200"]}]},{"DOI":"10.13039\/501100001809","name":"the Natural Science Foundation of China","doi-asserted-by":"crossref","award":["No. 31772162"],"award-info":[{"award-number":["No. 31772162"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["royalsocietypublishing.org"],"crossmark-restriction":true},"short-container-title":["Phil. Trans. R. Soc. B"],"published-print":{"date-parts":[[2019,3,4]]},"abstract":"<jats:p>\n                    Effector proteins present in aphid saliva are thought to modulate aphid\u2013plant interactions. Armet, an effector protein, is found in the phloem sap of pea-aphid-infested plants and is indispensable for the survival of aphids on plants. However, its function in plants has not been investigated. Here, we explored the functions of Armet after delivery into plants. Examination of the transcriptomes of\n                    <jats:italic>Nicotiana benthamiana<\/jats:italic>\n                    and\n                    <jats:italic>Medicago truncatula<\/jats:italic>\n                    following transgenic expression of Armet or infiltration of the protein showed that Armet activated pathways associated with plant\u2013pathogen interactions, mitogen-activated protein kinase and salicylic acid (SA). Armet induced a fourfold increase in SA accumulation by regulating the expression of\n                    <jats:italic>SAMT<\/jats:italic>\n                    and\n                    <jats:italic>SABP2<\/jats:italic>\n                    , two genes associated with SA metabolism, in Armet-infiltrated tobacco. The increase in SA enhanced the plants' resistance to bacterial pathogen\n                    <jats:italic>Pseudomonas syringae<\/jats:italic>\n                    but had no detectable adverse effects on aphid survival or reproduction. Similar molecular responses and a chlorosis phenotype were induced in tobacco by Armet from two aphid species but not by locust Armet, suggesting that the effector function of Armet may be specific for aphids. The results suggest that Armet causes plants to make a pathogen-resistance decision and reflect a novel tripartite insect\u2013plant\u2013pathogen interaction.\n                  <\/jats:p>\n                  <jats:p>This article is part of the theme issue \u2018Biotic signalling sheds light on smart pest management\u2019.<\/jats:p>","DOI":"10.1098\/rstb.2018.0314","type":"journal-article","created":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T04:44:13Z","timestamp":1547441053000},"page":"20180314","update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":67,"title":["Armet, an aphid effector protein, induces pathogen resistance in plants by promoting the accumulation of salicylic acid"],"prefix":"10.1098","volume":"374","author":[{"given":"Na","family":"Cui","sequence":"first","affiliation":[{"name":"State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, People's Republic of China"},{"name":"University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Lu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianzuo","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhao","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, People's Republic of China"},{"name":"University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4262-2329","authenticated-orcid":true,"given":"Le","family":"Kang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, People's Republic of China"},{"name":"University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6215-7159","authenticated-orcid":true,"given":"Feng","family":"Cui","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, People's Republic of China"},{"name":"University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"175","published-online":{"date-parts":[[2019,1,14]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0703535104"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1236011"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2013.00213"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1094\/MPMI-05-12-0119-FI"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1021\/pr100881q"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.1603\/EN10153"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/imb.12061"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-cellbio-092910-154055"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.1094\/MPMI.2002.15.10.1025"},{"key":"e_1_3_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2006.09.004"},{"key":"e_1_3_6_12_2","doi-asserted-by":"publisher","DOI":"10.1078\/0176-1617-0633"},{"key":"e_1_3_6_13_2","doi-asserted-by":"publisher","DOI":"10.1021\/jf020953b"},{"key":"e_1_3_6_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10886-004-7948-9"},{"key":"e_1_3_6_15_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.14-266023"},{"key":"e_1_3_6_16_2","unstructured":"Chabaud M Ratet P de Sousa Ara\u00fajo S Rold\u00e3o Lopes Amaral Duque AS Harrison M Barker DG. 2007 Agrobacterium tumefaciens -mediated transformation and in vitro plant regeneration of M. truncatula . In Medicago truncatula handbook March 2007 edn https:\/\/www.noble.org\/medicago-handbook\/2007."},{"key":"e_1_3_6_17_2","doi-asserted-by":"publisher","DOI":"10.2116\/analsci.28.1081"},{"key":"e_1_3_6_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/1744-7917.12336"},{"key":"e_1_3_6_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11427-017-9105-x"},{"key":"e_1_3_6_20_2","doi-asserted-by":"publisher","DOI":"10.1104\/pp.106.090035"},{"key":"e_1_3_6_21_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.phyto.050908.135202"},{"key":"e_1_3_6_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.crvi.2010.03.007"},{"key":"e_1_3_6_23_2","doi-asserted-by":"publisher","DOI":"10.1104\/pp.107.113142"},{"key":"e_1_3_6_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/arch.10065"},{"key":"e_1_3_6_25_2","doi-asserted-by":"publisher","DOI":"10.1303\/aez.2005.91"},{"key":"e_1_3_6_26_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-313X.2003.01902.x"},{"key":"e_1_3_6_27_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1147113"},{"key":"e_1_3_6_28_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0409227102"},{"key":"e_1_3_6_29_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0708958105"},{"key":"e_1_3_6_30_2","doi-asserted-by":"publisher","DOI":"10.1094\/MPMI-06-12-0144-FI"},{"key":"e_1_3_6_31_2","doi-asserted-by":"publisher","DOI":"10.1094\/MPMI-01-14-0018-R"},{"key":"e_1_3_6_32_2","doi-asserted-by":"publisher","DOI":"10.1094\/MPMI-05-13-0156-R"},{"key":"e_1_3_6_33_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1001216"},{"key":"e_1_3_6_34_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7601084"},{"key":"e_1_3_6_35_2","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.114.127373"}],"container-title":["Philosophical Transactions of the Royal Society B: Biological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rstb.2018.0314","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/royalsocietypublishing.org\/doi\/full-xml\/10.1098\/rstb.2018.0314","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rstb.2018.0314","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T21:26:12Z","timestamp":1778621172000},"score":1,"resource":{"primary":{"URL":"http:\/\/royalsocietypublishing.org\/rstb\/article\/42251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,14]]},"references-count":34,"journal-issue":{"issue":"1767","published-print":{"date-parts":[[2019,3,4]]}},"alternative-id":["10.1098\/rstb.2018.0314"],"URL":"https:\/\/doi.org\/10.1098\/rstb.2018.0314","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.735299085.793572233","asserted-by":"object"}]},"ISSN":["0962-8436","1471-2970"],"issn-type":[{"value":"0962-8436","type":"print"},{"value":"1471-2970","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,14]]},"assertion":[{"value":"2018-10-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}