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Trans. R. Soc. B"],"published-print":{"date-parts":[[2020,5,25]]},"abstract":"<jats:p>\n                    The brain likely uses offline periods to consolidate recent memories. One hypothesis holds that the hippocampal output provides a unique, global linking or \u2018index\u2019 code for each memory, and that this code is stored in the cortex in association with locally encoded attributes of each memory. Activation of the index code is hypothesized to evoke coordinated memory trace reactivation thus facilitating consolidation. Retrosplenial cortex (RSC) is a major recipient of hippocampal outflow and we have described populations of neurons there with sparse and orthogonal coding characteristics that resemble hippocampal \u2018place\u2019 cells, and whose expression depends on an intact hippocampus. Using two-photon Ca\n                    <jats:sup>2+<\/jats:sup>\n                    imaging, we recorded ensembles of neurons in the RSC during periods of immobility before and after active running on a familiar linear treadmill track. Synchronous bursting of distinct groups of neurons occurred during rest both prior to and after running. In the second rest epoch, these patterns were associated with the locations of tactile landmarks and reward. Complementing established views on the functions of the RSC, our findings indicate that the structure is involved with processing landmark information during rest.\n                  <\/jats:p>\n                  <jats:p>This article is part of the Theo Murphy meeting issue \u2018Memory reactivation: replaying events past, present and future\u2019.<\/jats:p>","DOI":"10.1098\/rstb.2019.0228","type":"journal-article","created":{"date-parts":[[2020,4,5]],"date-time":"2020-04-05T19:05:43Z","timestamp":1586113543000},"page":"20190228","update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":34,"title":["Coordinated activities of retrosplenial ensembles during resting-state encode spatial landmarks"],"prefix":"10.1098","volume":"375","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5981-5181","authenticated-orcid":true,"given":"HaoRan","family":"Chang","sequence":"first","affiliation":[{"name":"Canadian Centre for Behavioural Neuroscience, Department of Neuroscience, University of Lethbridge, Lethbridge, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid M.","family":"Esteves","sequence":"additional","affiliation":[{"name":"Canadian Centre for Behavioural Neuroscience, Department of Neuroscience, University of Lethbridge, Lethbridge, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam R.","family":"Neumann","sequence":"additional","affiliation":[{"name":"Canadian Centre for Behavioural Neuroscience, Department of Neuroscience, University of Lethbridge, Lethbridge, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianjun","family":"Sun","sequence":"additional","affiliation":[{"name":"Canadian Centre for Behavioural Neuroscience, Department of Neuroscience, University of Lethbridge, Lethbridge, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majid H.","family":"Mohajerani","sequence":"additional","affiliation":[{"name":"Canadian Centre for Behavioural Neuroscience, Department of Neuroscience, University of Lethbridge, Lethbridge, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2080-5258","authenticated-orcid":true,"given":"Bruce L.","family":"McNaughton","sequence":"additional","affiliation":[{"name":"Canadian Centre for Behavioural Neuroscience, Department of Neuroscience, University of Lethbridge, Lethbridge, Alberta, Canada"},{"name":"Department of Neurobiology and Behaviour, University of California, Irvine, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"175","published-online":{"date-parts":[[2020,4,6]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-1063(1997)7:2<146::AID-HIPO4>3.0.CO;2-L"},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2007.05745.x"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903150207"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902160207"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.450020102"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-199902250-00033"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/1467-9450.00233"},{"key":"e_1_3_7_9_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.08-06-01863.1988"},{"key":"e_1_3_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2004.04.005"},{"key":"e_1_3_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-4328(00)00312-0"},{"key":"e_1_3_7_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4058"},{"key":"e_1_3_7_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2017.04.036"},{"key":"e_1_3_7_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00243212"},{"key":"e_1_3_7_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4465"},{"key":"e_1_3_7_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-00180-9"},{"key":"e_1_3_7_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20958"},{"key":"e_1_3_7_18_2","first-page":"3713","article-title":"Retrosplenial cortical neurons encode navigational cues, trajectories and reward locations during goal directed navigation","volume":"27","author":"Vedder LC","year":"2017","journal-title":"Cereb. 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