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Trans. R. Soc. B"],"published-print":{"date-parts":[[2024,1,15]]},"abstract":"<jats:p>\n                    The World Health Organization has started a process to issue guidelines for the control of strongyloidiasis. The guidelines might recommend to implement preventive chemotherapy (PC) at community level (i.e. to all individuals above 5 years of age), over a defined prevalence threshold. We previously estimated the number of school-age children (SAC) who would need PC. Here we estimate the number of people above 15 years of age who might be included in PC for strongyloidiasis. Based on previous\n                    <jats:italic>Strongyloides<\/jats:italic>\n                    prevalence estimates and on countries' age distribution, we retrieved the number of adults in need of PC. We then subtracted the number of people already involved in ivermectin mass distribution for the elimination of onchocerciasis and lymphatic filariasis and people living in countries where\n                    <jats:italic>Loa loa<\/jats:italic>\n                    is endemic. The number of adults to be involved in PC was estimated at 905.4 (95% confidence interval (CI): 520.6\u20131177.2), 660.2 (95% CI: 512.7-1214.9), and 512.1 (95% CI: 276\u2013719.4) million people, when the strongyloidiasis prevalence threshold for implementing PC was set to 10%, 15% and 20%, respectively. Estimates at country level are also provided.These estimates might help endemic countries wishing to implement PC for strongyloidiasis to allocate resources to include adults in addition to SAC in control programmes.\n                  <\/jats:p>\n                  <jats:p>\n                    This article is part of the Theo Murphy meeting issue \u2018\n                    <jats:italic>Strongyloides<\/jats:italic>\n                    : omics to worm-free populations\u2019.\n                  <\/jats:p>","DOI":"10.1098\/rstb.2022.0433","type":"journal-article","created":{"date-parts":[[2023,11,26]],"date-time":"2023-11-26T19:05:15Z","timestamp":1701025515000},"update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Progress towards the implementation of control programmes for strongyloidiasis in endemic areas: estimation of number of adults in need of ivermectin for strongyloidiasis"],"prefix":"10.1098","volume":"379","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0108-6822","authenticated-orcid":true,"given":"Dora","family":"Buonfrate","sequence":"first","affiliation":[{"name":"Department of Infectious Tropical Diseases and Microbiology, IRCCS Sacro Cuore don Calabria Hospital, 370242, Negrar, Verona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Montresor","sequence":"additional","affiliation":[{"name":"Department of Control of Neglected Tropical Diseases, World Health Organization, 12024, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeno","family":"Bisoffi","sequence":"additional","affiliation":[{"name":"Department of Infectious Tropical Diseases and Microbiology, IRCCS Sacro Cuore don Calabria Hospital, 370242, Negrar, Verona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Tamarozzi","sequence":"additional","affiliation":[{"name":"Department of Infectious Tropical Diseases and Microbiology, IRCCS Sacro Cuore don Calabria Hospital, 370242, Negrar, Verona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donal","family":"Bisanzio","sequence":"additional","affiliation":[{"name":"Research Triangle Institute International, Washington, DC 20005-3967, USA"},{"name":"Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham, NG5 1PB, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"175","published-online":{"date-parts":[[2023,11,27]]},"reference":[{"key":"e_1_3_7_2_2","unstructured":"WHO. 2020 2030 targets for soil-transmitted helminthiases control programmes. See https:\/\/www.who.int\/publications\/i\/item\/9789240000315."},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0008505"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0002165"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004150"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0010561"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.1186\/s41182-018-0126-5"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0006943"},{"key":"e_1_3_7_9_2","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens9060468"},{"key":"e_1_3_7_10_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0009144"},{"key":"e_1_3_7_11_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-017-2196-9"},{"key":"e_1_3_7_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)09456-4"},{"key":"e_1_3_7_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40249-021-00858-9"},{"key":"e_1_3_7_14_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0009314"},{"key":"e_1_3_7_15_2","unstructured":"Bank W. 2023 World Bank open data. See https:\/\/data.worldbank.org\/. (Accessed 14 February 2023)."},{"key":"e_1_3_7_16_2","unstructured":"WHO. 2019 PCT Databank. See https:\/\/www.who.int\/teams\/control-of-neglected-tropical-diseases\/data-platforms\/pct-databank. (Accessed 14 February 2023)."},{"key":"e_1_3_7_17_2","unstructured":"WHO. 2019 The Global Health Observatory. See https:\/\/www.who.int\/data\/gho\/indicator-metadata-registry. (Accessed 5 October 2023)."},{"key":"e_1_3_7_18_2","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2883-2-S1-S7"},{"key":"e_1_3_7_19_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001210"},{"key":"e_1_3_7_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/bs.apar.2022.07.001"},{"key":"e_1_3_7_21_2","unstructured":"WHO. 2020 Diagnostic methods for the control of strongyloidiasis. In Virtual meeting 29 September 2020. See https:\/\/www.who.int\/publications\/i\/item\/9789240016538."},{"key":"e_1_3_7_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11908-008-0019-6"},{"key":"e_1_3_7_23_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0009561"},{"key":"e_1_3_7_24_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1003849"},{"key":"e_1_3_7_25_2","unstructured":"WHO. 2013 Prequalified medicinal products. See https:\/\/extranet.who.int\/prequal\/medicines\/prequalified-lists. (Accessed 14 February 2023)."},{"key":"e_1_3_7_26_2","doi-asserted-by":"crossref","unstructured":"Buonfrate D Montresor A Bisoffi Z Tamarozzi F Bisanzio D. 2023 Progress towards the implementation of control programmes for strongyloidiasis in endemic areas: estimation of number of adults in need of ivermectin for strongyloidiasis. Figshare. 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