{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T14:10:14Z","timestamp":1784815814206,"version":"3.55.0"},"reference-count":77,"publisher":"The Royal Society","issue":"1955","license":[{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004189","name":"Max Planck Society","doi-asserted-by":"publisher","award":["MFFALIMN0001"],"award-info":[{"award-number":["MFFALIMN0001"]}],"id":[{"id":"10.13039\/501100004189","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004807","name":"DFG","doi-asserted-by":"publisher","award":["SFB 1372"],"award-info":[{"award-number":["SFB 1372"]}],"id":[{"id":"10.13039\/100004807","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Magnetoreception and Navigation in Vertebrates","award":["395940726"],"award-info":[{"award-number":["395940726"]}]},{"DOI":"10.13039\/501100004837","name":"Spanish Ministry of Science, Innovation and Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["PGC2018-097575-B-I00"],"award-info":[{"award-number":["PGC2018-097575-B-I00"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["PID2022-140091NB-I00"],"award-info":[{"award-number":["PID2022-140091NB-I00"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["1R35GM151012"],"award-info":[{"award-number":["1R35GM151012"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Seasonal migratory animals can evolve residency through adaptation. The threshold model of quantitative genetics predicts that residency evolves from migrants when genetic variation for lower liability, or a latent state underlying migratory propensity, is positively selected. However, it is unknown what cellular and molecular regulations underlie this process. The hypothalamus, which regulates physiology and behaviour of vertebrates by integrating internal and environmental conditions, is a strong candidate structure where migratory propensity may be regulated. To understand the hypothalamic molecular regulation underlying the evolutionary change to residency, we use the Eurasian blackcap system comprising ancestral migratory and derived resident populations. By combining a common-garden experiment with single-cell epigenetics, we compare genomic regions with open chromatin between migratory and resident populations and seasons. We find that the seasonal change in chromatin accessibility is reduced in residents across major cell types. This suggests that the evolutionary transition to residency involves a reduction in the amplitude of seasonal change in epigenetic states in multiple hypothalamic cell types, which may collectively represent migratory liability. Environmental shifts, such as deglaciation for blackcaps, may play an important role in exposing and selecting variation in the seasonal reaction norm of liability underlying the evolution of seasonal plastic traits.<\/jats:p>\n                  <jats:p>This article is part of the theme issue \u2018Ecological epigenetics at the intersection of behaviour and life history variation in non-model animals\u2019.<\/jats:p>","DOI":"10.1098\/rstb.2025.0022","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T13:48:16Z","timestamp":1784814496000},"source":"Crossref","is-referenced-by-count":0,"title":["Differential epigenetic regulation underlies evolutionary transition of seasonal migration"],"prefix":"10.1098","volume":"381","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5713-9391","authenticated-orcid":false,"given":"Jun","family":"Ishigohoka","sequence":"first","affiliation":[{"name":"Max Planck Institute for Evolutionary Biology 1 , Pl\u00f6n, Schleswig-Holstein, Germany"},{"name":"Friedrich Miescher Laboratory of the Max Planck Society 2 , T\u00fcbingen, Baden-W\u00fcrttemberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Sebastian Lugo","family":"Ramos","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Evolutionary Biology 1 , Pl\u00f6n, Schleswig-Holstein, Germany"},{"name":"The Francis Crick Institute 3 , London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gillian","family":"Durieux","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Evolutionary Biology 1 , Pl\u00f6n, Schleswig-Holstein, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Reinsch","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Evolutionary Biology 1 , Pl\u00f6n, Schleswig-Holstein, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4108-9729","authenticated-orcid":false,"given":"Kira","family":"Delmore","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Evolutionary Biology 1 , Pl\u00f6n, Schleswig-Holstein, Germany"},{"name":"Columbia University 4 , New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah C.","family":"Justen","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Evolutionary Biology 1 , Pl\u00f6n, Schleswig-Holstein, Germany"},{"name":"University of California Davis 5 , Davis, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Illera","sequence":"additional","affiliation":[{"name":"Research Unit of Biodiversity, University of Oviedo 6 , Oviedo, Asturias, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5535-3100","authenticated-orcid":false,"given":"Javier","family":"Perez-Tris","sequence":"additional","affiliation":[{"name":"Zoology and Physical Anthropology, Complutense University of Madrid 7 , Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8372-8560","authenticated-orcid":false,"given":"Miriam","family":"Liedvogel","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Evolutionary Biology 1 , Pl\u00f6n, Schleswig-Holstein, Germany"},{"name":"Institute of Avian Research 8 , Wilhelmshaven, Niedersachsen, Germany"},{"name":"Carl von Ossietzky Universit\u00e4t Oldenburg 9 , Oldenburg, Niedersachsen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"175","published-online":{"date-parts":[[2026,7,23]]},"reference":[{"key":"2026072309481212400_bib1","doi-asserted-by":"crossref","DOI":"10.1093\/acprof:oso\/9780199640386.001.0001","volume-title":"Migration: the biology of life on the move","author":"Dingle","year":"2014","edition":"2nd edn."},{"key":"2026072309481212400_bib2","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.tree.2011.07.009","article-title":"The genetics of migration on the move","volume":"26","author":"Liedvogel","year":"2011","journal-title":"Trends Ecol. Evol."},{"key":"2026072309481212400_bib3","volume-title":"The migration ecology of birds","author":"Newton","year":"2008"},{"key":"2026072309481212400_bib4","doi-asserted-by":"crossref","DOI":"10.1093\/acprof:oso\/9780199677184.001.0001","volume-title":"Animal movement across scales","author":"Hansson","year":"2014"},{"key":"2026072309481212400_bib5","volume-title":"Bird migration: a general survey","author":"Berthold","year":"1993","edition":"1st edn."},{"key":"2026072309481212400_bib6","volume-title":"Control of bird migration","author":"Berthold","year":"1996"},{"key":"2026072309481212400_bib7","doi-asserted-by":"crossref","first-page":"e28123","DOI":"10.7554\/eLife.28123","article-title":"Migration confers winter survival benefits in a partially migratory songbird","volume":"6","author":"Z\u00fa\u00f1iga","year":"2017","journal-title":"eLife"},{"key":"2026072309481212400_bib8","doi-asserted-by":"crossref","first-page":"20200928","DOI":"10.1098\/rspb.2020.0928","article-title":"Among-individual and within-individual variation in seasonal migration covaries with subsequent reproductive success in a partially migratory bird","volume":"287","author":"Reid","year":"2020","journal-title":"Proc. R. Soc. B"},{"key":"2026072309481212400_bib9","first-page":"12115","article-title":"Temperate origins of long-distance seasonal migration in New World songbirds","volume-title":"Proc. Natl Acad. Sci. USA","author":"Winger","year":"2014"},{"key":"2026072309481212400_bib10","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/jbi.13700","article-title":"Reconstructing the geographic and climatic origins of long-distance bird migrations","volume":"47","author":"Dufour","year":"2020","journal-title":"J. Biogeogr."},{"key":"2026072309481212400_bib11","first-page":"14642","article-title":"Frequency of migrants and migratory activity are genetically correlated in a bird population: evolutionary implications","volume-title":"Proc. Natl Acad. Sci. USA","author":"Pulido","year":"1996"},{"key":"2026072309481212400_bib12","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1111\/j.1600-0706.2011.19844.x","article-title":"Evolutionary genetics of partial migration \u2013 the threshold model of migration revis(it)ed","volume":"120","author":"Pulido","year":"2011","journal-title":"Oikos"},{"key":"2026072309481212400_bib13","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1641\/B570211","article-title":"The genetics and evolution of avian migration","volume":"57","author":"Pulido","year":"2007","journal-title":"BioScience"},{"key":"2026072309481212400_bib14","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1111\/1365-2656.13410","article-title":"Strong survival selection on seasonal migration versus residence induced by extreme climatic events","volume":"90","author":"Acker","year":"2021","journal-title":"J. Anim. Ecol."},{"key":"2026072309481212400_bib15","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1046\/j.1420-9101.1998.1030195.x","article-title":"Evolutionary aspects of migratory behavior in European warblers","volume":"1","author":"Berthold","year":"1988","journal-title":"J. Evol. Biol."},{"key":"2026072309481212400_bib16","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1126\/science.212.4490.77","article-title":"Genetic basis of migratory behavior in European warblers","volume":"212","author":"Berthold","year":"1981","journal-title":"Science"},{"key":"2026072309481212400_bib17","doi-asserted-by":"crossref","first-page":"7341","DOI":"10.1073\/pnas.0910361107","article-title":"Current selection for lower migratory activity will drive the evolution of residency in a migratory bird population","volume":"107","author":"Pulido","year":"2010","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"2026072309481212400_bib18","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1111\/evo.14408","article-title":"Properties of phenotypic plasticity in discrete threshold traits","volume":"76","author":"Reid","year":"2022","journal-title":"Evolution"},{"key":"2026072309481212400_bib19","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1126\/science.adh8488","article-title":"The structural and functional complexity of the integrative hypothalamus","volume":"382","author":"Fong","year":"2023","journal-title":"Science"},{"key":"2026072309481212400_bib20","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1111\/ejn.14994","article-title":"Hypothalamic plasticity in response to changes in photoperiod and food quality: an adaptation to support pre-migratory fattening in songbirds?","volume":"53","author":"Majumdar","year":"2021","journal-title":"Eur. J. Neurosci."},{"key":"2026072309481212400_bib21","doi-asserted-by":"crossref","first-page":"e70065","DOI":"10.1371\/journal.pone.0070065","article-title":"Neural correlates of migration: activation of hypothalamic clock(s) in and out of migratory state in the blackheaded bunting (Emberiza melanocephala)","volume":"8","author":"Rastogi","year":"2013","journal-title":"PLoS ONE"},{"key":"2026072309481212400_bib22","doi-asserted-by":"crossref","first-page":"12823","DOI":"10.1038\/s41598-021-91951-4","article-title":"Photoperiodically driven transcriptome-wide changes in the hypothalamus reveal transcriptional differences between physiologically contrasting seasonal life-history states in migratory songbirds","volume":"11","author":"Sharma","year":"2021","journal-title":"Sci. Rep."},{"key":"2026072309481212400_bib23","doi-asserted-by":"crossref","first-page":"2775","DOI":"10.1007\/s00429-020-02154-y","article-title":"Concurrent changes in photoperiod-induced seasonal phenotypes and hypothalamic CART peptide-containing systems in night-migratory redheaded buntings","volume":"225","author":"Singh","year":"2020","journal-title":"Brain Struct. Funct."},{"key":"2026072309481212400_bib24","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/s00359-017-1193-5","article-title":"Neural control of daily and seasonal timing of songbird migration","volume":"203","author":"Stevenson","year":"2017","journal-title":"J. Comp. Physiol. A"},{"key":"2026072309481212400_bib25","doi-asserted-by":"crossref","first-page":"20181735","DOI":"10.1098\/rspb.2018.1735","article-title":"Seasonally sympatric but allochronic: differential expression of hypothalamic genes in a songbird during gonadal development","volume":"285","author":"Bauer","year":"2018","journal-title":"Proc. R. Soc. B"},{"key":"2026072309481212400_bib26","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1098\/rsbl.2009.0193","article-title":"Stress hormone dynamics: an adaptation to migration?","volume":"5","author":"Nilsson","year":"2009","journal-title":"Biol. Lett."},{"key":"2026072309481212400_bib27","doi-asserted-by":"crossref","first-page":"e70131","DOI":"10.1002\/ecy.70131","article-title":"Bird migration on the edge: experimental manipulation of corticosterone advances departure dates","volume":"106","author":"Hoarau","year":"2025","journal-title":"Ecology"},{"key":"2026072309481212400_bib28","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.yhbeh.2016.05.021","article-title":"Regulation of vernal migration in Gambel\u2019s white-crowned sparrows: role of thyroxine and triiodothyronine","volume":"84","author":"P\u00e9rez","year":"2016","journal-title":"Horm. Behav."},{"key":"2026072309481212400_bib29","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1073\/pnas.1619565114","article-title":"Ghrelin affects stopover decisions and food intake in a long-distance migrant","volume":"114","author":"Goymann","year":"2017","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"2026072309481212400_bib30","doi-asserted-by":"crossref","first-page":"16651","DOI":"10.1073\/pnas.1310643110","article-title":"Reversible DNA methylation regulates seasonal photoperiodic time measurement","volume":"110","author":"Stevenson","year":"2013","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"2026072309481212400_bib31","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1007\/s00359-023-01673-3","article-title":"Epigenetics and seasonal timing in animals: a concise review","volume":"210","author":"Fishman","year":"2023","journal-title":"J. Comp. Physiol. A"},{"key":"2026072309481212400_bib32","volume-title":"Sylvia warblers: identification, taxonomy and phylogeny of the genus Sylvia","author":"Shirihai","year":"2001"},{"key":"2026072309481212400_bib33","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1186\/1471-2148-11-163","article-title":"Palaeoclimatic events, dispersal and migratory losses along the Afro-European axis as drivers of biogeographic distribution in Sylvia warblers","volume":"11","author":"Voelker","year":"2011","journal-title":"BMC Evol. Biol."},{"key":"2026072309481212400_bib34","doi-asserted-by":"crossref","first-page":"e54462","DOI":"10.7554\/eLife.54462","article-title":"The evolutionary history and genomics of European blackcap migration","volume":"9","author":"Delmore","year":"2020","journal-title":"eLife"},{"key":"2026072309481212400_bib35","doi-asserted-by":"crossref","first-page":"iyaf004","DOI":"10.1093\/genetics\/iyaf004","article-title":"High-recombining genomic regions affect demography inference based on ancestral recombination graphs","volume":"229","author":"Ishigohoka","year":"2025","journal-title":"Genetics"},{"key":"2026072309481212400_bib36","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0065-3454(03)33004-9","article-title":"Genetic basis and evolutionary aspects of bird migration","volume":"33","author":"Berthold","year":"2003","journal-title":"Adv. Study. Behav."},{"key":"2026072309481212400_bib37","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/978-3-662-05957-9_4","article-title":"Quantitative genetic analysis of migratory behaviour","volume-title":"Avian migration","author":"Pulido","year":"2003"},{"key":"2026072309481212400_bib38","doi-asserted-by":"crossref","first-page":"e0209331","DOI":"10.1371\/journal.pone.0209331","article-title":"Rethomics: an R framework to analyse high-throughput behavioural data","volume":"14","author":"Geissmann","year":"2019","journal-title":"PLoS ONE"},{"key":"2026072309481212400_bib39","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1038\/s41592-021-01282-5","article-title":"Single-cell chromatin state analysis with Signac","volume":"18","author":"Stuart","year":"2021","journal-title":"Nat. Methods"},{"key":"2026072309481212400_bib40","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/nbt.3192","article-title":"Spatial reconstruction of single-cell gene expression data","volume":"33","author":"Satija","year":"2015","journal-title":"Nat. Biotechnol."},{"key":"2026072309481212400_bib41","doi-asserted-by":"crossref","first-page":"3573","DOI":"10.1016\/j.cell.2021.04.048","article-title":"Integrated analysis of multimodal single-cell data","volume":"184","author":"Hao","year":"2021","journal-title":"Cell"},{"key":"2026072309481212400_bib42","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1038\/s41587-023-01767-y","article-title":"Dictionary learning for integrative, multimodal and scalable single-cell analysis","volume":"42","author":"Hao","year":"2024","journal-title":"Nat. Biotechnol."},{"key":"2026072309481212400_bib43","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1038\/s41592-019-0619-0","article-title":"Fast, sensitive and accurate integration of single-cell data with Harmony","volume":"16","author":"Korsunsky","year":"2019","journal-title":"Nat. Methods"},{"key":"2026072309481212400_bib44","doi-asserted-by":"crossref","first-page":"R137","DOI":"10.1186\/gb-2008-9-9-r137","article-title":"Model-based analysis of ChIP-Seq (MACS)","volume":"9","author":"Zhang","year":"2008","journal-title":"Genome Biol."},{"key":"2026072309481212400_bib45","doi-asserted-by":"crossref","first-page":"eabd9704","DOI":"10.1126\/science.abd9704","article-title":"Cellular transcriptomics reveals evolutionary identities of songbird vocal circuits","volume":"371","author":"Colquitt","year":"2021","journal-title":"Science"},{"key":"2026072309481212400_bib46","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1038\/s42003-021-02146-6","article-title":"NEBULA is a fast negative binomial mixed model for differential or co-expression analysis of large-scale multi-subject single-cell data","volume":"4","author":"He","year":"2021","journal-title":"Commun. Biol."},{"key":"2026072309481212400_bib47","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.molcel.2018.06.044","article-title":"Cicero predicts cis-regulatory DNA interactions from single-cell chromatin accessibility data","volume":"71","author":"Pliner","year":"2018","journal-title":"Mol. Cell"},{"key":"2026072309481212400_bib48","doi-asserted-by":"crossref","first-page":"e73749","DOI":"10.1002\/ece3.73749","article-title":"Shifting balancing selection underlies an inversion cline in eurasian blackcap","volume":"16","author":"Ishigohoka","year":"2026","journal-title":"Ecol. Evol."},{"key":"2026072309481212400_bib49","doi-asserted-by":"crossref","first-page":"20200867","DOI":"10.1098\/rspb.2020.0867","article-title":"Genetic growth potential, rather than phenotypic size, predicts migration phenotype in Atlantic salmon","volume":"287","author":"Debes","year":"2020","journal-title":"Proc. R. Soc. B"},{"key":"2026072309481212400_bib50","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1007\/s004420050220","article-title":"Geographic variation in critical photoperiod for diapause induction and its temperature dependence in Hyphantria cunea Drury (Lepidoptera: Arctiidae)","volume":"111","author":"Gomi","year":"1997","journal-title":"Oecologia"},{"key":"2026072309481212400_bib51","doi-asserted-by":"crossref","first-page":"3569","DOI":"10.1098\/rspb.2010.0877","article-title":"Diet and hormonal manipulation reveal cryptic genetic variation: implications for the evolution of novel feeding strategies","volume":"277","author":"Led\u00f3n-Rettig","year":"2010","journal-title":"Proc. R. Soc. B"},{"key":"2026072309481212400_bib52","doi-asserted-by":"crossref","first-page":"2830","DOI":"10.1111\/j.1558-5646.2011.01392.x","article-title":"High temperatures reveal cryptic genetic variation in a polymorphic female sperm storage organ","volume":"65","author":"Berger","year":"2011","journal-title":"Evolution"},{"key":"2026072309481212400_bib53","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1111\/j.1558-5646.2010.01195.x","article-title":"Cryptic genetic variation and body size evolution in threespine stickleback","volume":"65","author":"McGuigan","year":"2011","journal-title":"Evolution"},{"key":"2026072309481212400_bib54","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1111\/evo.14119","article-title":"Genetic variance in fitness and its cross-sex covariance predict adaptation during experimental evolution","volume":"74","author":"Koch","year":"2020","journal-title":"Evolution"},{"key":"2026072309481212400_bib55","doi-asserted-by":"crossref","first-page":"102839","DOI":"10.1016\/j.jtherbio.2021.102839","article-title":"Elevated ambient temperature accelerates aspects of torpor phenology in an obligate hibernator","volume":"96","author":"MacCannell","year":"2021","journal-title":"J. Therm. Biol."},{"key":"2026072309481212400_bib56","doi-asserted-by":"crossref","first-page":"160002","DOI":"10.1098\/rsos.160002","article-title":"Decreases in body temperature and body mass constitute pre-hibernation remodelling in the Syrian golden hamster, a facultative mammalian hibernator","volume":"3","author":"Chayama","year":"2016","journal-title":"R. Soc. Open Sci."},{"key":"2026072309481212400_bib57","doi-asserted-by":"crossref","first-page":"109162","DOI":"10.1016\/j.quascirev.2024.109162","article-title":"Changes in distribution of the Iberian vegetation since the Last Glacial Maximum: a model-based approach","volume":"351","author":"Casas-Gallego","year":"2025","journal-title":"Quat. Sci. Rev."},{"key":"2026072309481212400_bib58","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.quaint.2022.04.012","article-title":"High-frequency vegetation and climatic changes during the Late\u00a0glacial inferred from the Lapsou pollen record (Cantal, southern Massif Central, France)","volume":"636","author":"Duprat-Oualid","year":"2022","journal-title":"Quat. Int."},{"key":"2026072309481212400_bib59","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0031-0182(94)90182-1","article-title":"Pollen analysis of a deep-sea core in the Gulf of Guinea: vegetation and climatic changes during the last 225,000\u00a0years B.P","volume":"109","author":"Fr\u00e9doux","year":"1994","journal-title":"Palaeogeogr. Palaeoclimatol. Palaeoecol."},{"key":"2026072309481212400_bib60","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.quascirev.2016.11.022","article-title":"Vegetation of Eurasia from the Last Glacial Maximum to present: key biogeographic patterns","volume":"157","author":"Binney","year":"2017","journal-title":"Quat. Sci. Rev."},{"key":"2026072309481212400_bib61","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1016\/j.quascirev.2008.08.016","article-title":"A coastal reservoir of biodiversity for Upper Pleistocene human populations: palaeoecological investigations in Gorham\u2019s Cave (Gibraltar) in the context of the Iberian Peninsula","volume":"27","author":"Carri\u00f3n","year":"2008","journal-title":"Quat. Sci. Rev."},{"key":"2026072309481212400_bib62","first-page":"511","article-title":"Long-term dynamics of Mediterranean frugivorous birds and fleshy fruits: a 12-year study","volume":"68","author":"Herrera","year":"1998","journal-title":"Ecol. Monogr."},{"key":"2026072309481212400_bib63","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1111\/j.1474-919X.1981.tb04055.x","article-title":"The frugivorous det of blackcap populations Sylvia atricapilla wintering in southern Spain","volume":"123","author":"Jordano","year":"1981","journal-title":"Ibis"},{"key":"2026072309481212400_bib64","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1006\/jasc.1995.0037","article-title":"A palaeoenvironmental study in semi-arid southeastern Spain: the palynological and sedimentological sequence at Perneras Cave (Lorca, Murcia)","volume":"22","author":"Carri\u00f3n","year":"1995","journal-title":"J. Archaeol. Sci."},{"key":"2026072309481212400_bib65","first-page":"31","article-title":"The African rain forest \u2013 main characteristics of changes in vegetation and climate from the Upper Cretaceous to the Quaternary","volume":"104","author":"Maley","year":"1996","journal-title":"Proc. R. Soc. Edin. B"},{"key":"2026072309481212400_bib66","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.5194\/cp-20-1939-2024","article-title":"The climate and vegetation of Europe, northern Africa, and the Middle East during the Last Glacial Maximum (21 000\u00a0yr BP) based on pollen data","volume":"20","author":"Davis","year":"2024","journal-title":"Clim. Past"},{"key":"2026072309481212400_bib67","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1111\/1365-2745.14422","article-title":"Higher abundance of disturbance-favoured trees and shrubs in European temperate woodlands prior to the Late-Quaternary extinction of megafauna","volume":"112","author":"Pearce","year":"2024","journal-title":"J. Ecol."},{"key":"2026072309481212400_bib68","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/0169-5347(91)90072-6","article-title":"Genetic control of migratory behaviour in birds","volume":"6","author":"Berthold","year":"1991","journal-title":"Trends Ecol. Evol."},{"key":"2026072309481212400_bib69","doi-asserted-by":"crossref","first-page":"109576","DOI":"10.1016\/j.quascirev.2025.109576","article-title":"Millennial-scale climatic variability and fire regimes and their impacts on vegetation in Gran Canaria since 28 cal ka BP","volume":"369","author":"Martin-Ramos","year":"2025","journal-title":"Quat. Sci. Rev."},{"key":"2026072309481212400_bib70","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1111\/j.1461-0248.2004.00715.x","article-title":"Ecological speciation","volume":"8","author":"Rundle","year":"2005","journal-title":"Ecol. Lett."},{"key":"2026072309481212400_bib71","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1126\/science.abg0718","article-title":"A chromosomal inversion contributes to divergence in multiple traits between deer mouse ecotypes","volume":"377","author":"Hager","year":"2022","journal-title":"Science"},{"key":"2026072309481212400_bib72","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1086\/285404","article-title":"Ecological character displacement and speciation in Sticklebacks","volume":"140","author":"Schluter","year":"1992","journal-title":"Am. Nat."},{"key":"2026072309481212400_bib73","doi-asserted-by":"crossref","first-page":"e2300673120","DOI":"10.1073\/pnas.2300673120","article-title":"Complex evolutionary processes maintain an ancient chromosomal inversion","volume":"120","author":"Nosil","year":"2023","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"2026072309481212400_bib74","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1093\/auk\/100.3.601","article-title":"Genetic determination of partial migration in the European robin (Erithacus rubecula)","volume":"100","author":"Biebach","year":"1983","journal-title":"Auk"},{"key":"2026072309481212400_bib75","doi-asserted-by":"crossref","first-page":"e98562","DOI":"10.1371\/journal.pone.0098562","article-title":"Site fidelity and individual variation in winter location in partially migratory European shags","volume":"9","author":"Grist","year":"2014","journal-title":"PLoS ONE"},{"key":"2026072309481212400_bib76","doi-asserted-by":"crossref","first-page":"181","DOI":"10.5194\/cp-7-181-2011","article-title":"Refugia of marine fish in the Northeast Atlantic during the Last Glacial Maximum: concordant assessment from archaeozoology and palaeotemperature reconstructions","volume":"7","author":"Kettle","year":"2011","journal-title":"Clim. Past"},{"key":"2026072309481212400_bib77","article-title":"Differential epigenetic regulation underlies evolutionary transition of seasonal migration","author":"Ishigohoka","year":"2026"}],"container-title":["Philosophical Transactions of the Royal Society B: Biological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/royalsocietypublishing.org\/rstb\/article-pdf\/doi\/10.1098\/rstb.2025.0022\/6153627\/rstb.2025.0022.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/royalsocietypublishing.org\/rstb\/article-pdf\/doi\/10.1098\/rstb.2025.0022\/6153627\/rstb.2025.0022.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T13:48:28Z","timestamp":1784814508000},"score":1,"resource":{"primary":{"URL":"https:\/\/royalsocietypublishing.org\/rstb\/article\/381\/1955\/20250022\/482592\/Differential-epigenetic-regulation-underlies"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,23]]},"references-count":77,"journal-issue":{"issue":"1955","published-online":{"date-parts":[[2026,7,23]]},"published-print":{"date-parts":[[2026,7,23]]}},"URL":"https:\/\/doi.org\/10.1098\/rstb.2025.0022","relation":{},"ISSN":["0962-8436","1471-2970"],"issn-type":[{"value":"0962-8436","type":"print"},{"value":"1471-2970","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,23]]},"article-number":"20250022"}}