{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T05:18:24Z","timestamp":1788067104468,"version":"build-2784847793"},"reference-count":7,"publisher":"Microbiology Society","issue":"2","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,2,1]]},"abstract":"\n \n \n Bacillus cereus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> is a common laboratory and environmental contaminant. Reports of severe infections are mainly limited to immunocompromised individuals. In reported cases, the time interval between bacteraemia and neuro-invasion appears to be very short, highlighting the importance of rapid and definitive identification and susceptibility testing of invasive \n \n B. cereus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>. We report a case of a neonatal \n \n B. cereus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> bacteraemia complicated by a brain abscess from a neonatal intensive care unit. The neonate presented with bradycardia and desaturations with increased oxygen requirements. Initial blood culture detected \n \n B. cereus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> but was considered a contaminant. Repeated culturing of the Gram-positive rod was subsequently considered to be significant. Initial ultrasound head scans revealed echogenicity in the right posterior deep white matter. A large central cavity (5 mm diameter) could eventually be observed. The brain abscess resolved after surgical drainage and an extensive 6 weeks of antimicrobial therapy. This case study describes a rare event that illustrates the importance of rapid identification and susceptibility testing of invasive \n \n B. cereus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> isolates from immunocompromised patients.<\/jats:p>","DOI":"10.1099\/acmi.0.000080","type":"journal-article","created":{"date-parts":[[2019,11,27]],"date-time":"2019-11-27T16:12:17Z","timestamp":1574871137000},"source":"Crossref","is-referenced-by-count":4,"title":["Bacillus cereus bacteraemia complicated by a brain abscess in a pre-term neonate"],"prefix":"10.1099","volume":"2","author":[{"given":"Harsha","family":"Samarasekara","sequence":"first","affiliation":[{"name":"Department of Microbiology and Infectious Diseases, New South Wales Health Pathology, Nepean Blue Mountains Pathology Service, PO Box 63, Penrith, New South Wales, 2751, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Janto","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Infectious Diseases, New South Wales Health Pathology, Nepean Blue Mountains Pathology Service, PO Box 63, Penrith, New South Wales, 2751, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishnu","family":"Dasireddy","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, Nepean Hospital, Penrith, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6567-2962","authenticated-orcid":false,"given":"Adam","family":"Polkinghorne","sequence":"additional","affiliation":[{"name":"The University of Sydney Nepean Clinical School, Faculty of Medicine and Health, University of Sydney, Penrith, New South Wales, 2751, Australia"},{"name":"Department of Microbiology and Infectious Diseases, New South Wales Health Pathology, Nepean Blue Mountains Pathology Service, PO Box 63, Penrith, New South Wales, 2751, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1264-3970","authenticated-orcid":false,"given":"James","family":"Branley","sequence":"additional","affiliation":[{"name":"The University of Sydney Nepean Clinical School, Faculty of Medicine and Health, University of Sydney, Penrith, New South Wales, 2751, Australia"},{"name":"Department of Microbiology and Infectious Diseases, New South Wales Health Pathology, Nepean Blue Mountains Pathology Service, PO Box 63, Penrith, New South Wales, 2751, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00073-09"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0194346"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0b013e31828e5455"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1159\/000325073"},{"key":"R5","volume-title":"Methods for Antimicrobial dilution and disk susceptibility testing of infrequently isolated or fastidious bacteria: Approved Guideline \u2013","year":"2010"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1754.1999.00405.x"},{"key":"R7","article-title":"Bacillus cereus bloodstream infection in a preterm neonate complicated by late meningitis","volume":"2012","author":"Horii","year":"2012","journal-title":"Case Rep Infect Dis"}],"container-title":["Access Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/acmi\/10.1099\/acmi.0.000080?crawler=true&mimetype=application\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T05:33:03Z","timestamp":1702618383000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/acmi\/10.1099\/acmi.0.000080"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,1]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2,1]]}},"URL":"https:\/\/doi.org\/10.1099\/acmi.0.000080","relation":{},"ISSN":["2516-8290"],"issn-type":[{"value":"2516-8290","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,1]]}}}