{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T19:09:24Z","timestamp":1788635364077,"version":"build-2803163510"},"reference-count":33,"publisher":"Microbiology Society","issue":"5","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,5,1]]},"abstract":"<jats:p>CNS infection is a life-threatening condition in developing countries and <jats:italic>\n                     <jats:named-content content-type=\"species\">\n                        <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/doi.org\/10.1601\/nm.5677\" xlink:type=\"simple\">Streptococcus pneumoniae<\/jats:ext-link>\n                     <\/jats:named-content>\n                  <\/jats:italic> has been reported as the most common cause of bacterial meningitis; however, there is limited data on pneumococcal meningitis in Indonesia. This cross-sectional study aimed to isolate and identity <jats:italic>\n                     <jats:named-content content-type=\"species\">\n                        <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/doi.org\/10.1601\/nm.5677\" xlink:type=\"simple\">S. pneumoniae<\/jats:ext-link>\n                     <\/jats:named-content>\n                  <\/jats:italic> strains from cerebrospinal fluid (CSF) specimens collected as part of routine testing from patients with clinically diagnosed central nervous system infection at a national referral hospital in Jakarta, Indonesia in 2017. <jats:italic>\n                     <jats:named-content content-type=\"species\">\n                        <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/doi.org\/10.1601\/nm.5677\" xlink:type=\"simple\">S. pneumoniae<\/jats:ext-link>\n                     <\/jats:named-content>\n                  <\/jats:italic> isolation and identification were performed using conventional culture and molecular tools. Antibiotic susceptibility patterns were monitored through minimum inhibitory concentration testing. From 147 CSF specimens, one <jats:italic>\n                     <jats:named-content content-type=\"species\">\n                        <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/doi.org\/10.1601\/nm.5677\" xlink:type=\"simple\">S. pneumoniae<\/jats:ext-link>\n                     <\/jats:named-content>\n                  <\/jats:italic> strain was identified from a patient with bacterial meningitis symptoms. The isolate was serotype 6B (ST5661) and susceptible to 18 antimicrobial agents tested, including penicillin, tetracycline, and the macrolide group. Our data provide insights into the epidemiology of invasive pneumococcal disease in Indonesia.<\/jats:p>","DOI":"10.1099\/acmi.0.000123","type":"journal-article","created":{"date-parts":[[2020,3,26]],"date-time":"2020-03-26T15:16:00Z","timestamp":1585235760000},"source":"Crossref","is-referenced-by-count":6,"title":["Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia"],"prefix":"10.1099","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9349-3937","authenticated-orcid":false,"given":"Diana Shintawati","family":"Purwanto","sequence":"first","affiliation":[{"name":"Department of Biochemistry, Faculty of Medicine Sam Ratulangi University, Manado, Indonesia"},{"name":"Department of Clinical Pathology, Faculty of Medicine Universitas Indonesia\/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7503-2395","authenticated-orcid":false,"given":"Tonny","family":"Loho","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology, Faculty of Medicine Universitas Indonesia\/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wisnu","family":"Tafroji","sequence":"additional","affiliation":[{"name":"Molecular Bacteriology Unit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irawan","family":"Mangunatmadja","sequence":"additional","affiliation":[{"name":"Department of Child Health, Faculty of Medicine Universitas Indonesia\/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanna","family":"Immanuel","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology, Faculty of Medicine Universitas Indonesia\/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3730-6727","authenticated-orcid":false,"given":"Ina Susianti","family":"Timan","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology, Faculty of Medicine Universitas Indonesia\/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1964-0561","authenticated-orcid":false,"given":"Yusra","family":"Yusra","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology, Faculty of Medicine Universitas Indonesia\/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7639-7441","authenticated-orcid":false,"given":"Dodi","family":"Safari","sequence":"additional","affiliation":[{"name":"Molecular Bacteriology Unit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00118-13"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1038\/srep02382"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(13)70332-3"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1005384"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0197198"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-015-0787-1"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e318275614b"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiz301"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1212\/CPJ.0000000000000517"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.2.734-740.2004"},{"key":"R11","article-title":"Laboratory Methods for the Diagnosis of Meningitis caused by Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus inf luenzae. 2nd edition. 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