{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T03:22:17Z","timestamp":1775618537672,"version":"3.50.1"},"reference-count":14,"publisher":"Microbiology Society","issue":"8","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,8,1]]},"abstract":"<jats:p>Zygomycosis and aspergillosis are two serious fungal infections that are commonly seen in immunocompromised patients. Since both of these infections involve fungi that invade vessels of the arterial system, an early and rapid diagnosis by direct examination of KOH mounts of the relevant clinical sample can clinch the diagnosis. Here, we present a case of a 60-year-old diabetic patient who presented with swelling and pain over the nose and left eye for 7\u2009days with loss of vision in the left eye. After investigation, the patient was diagnosed as having rhinocerebral mucormycosis and aspergillosis, and was initially treated with amphotericin B (1\u2009mg kg<jats:sup>\u22121<\/jats:sup> day<jats:sup>\u22121<\/jats:sup> intravenously), followed by endoscopic debridement under general anaesthesia. The patient gradually improved after surgery, and treatment with intravenous amphotericin B was continued along with the addition of 200\u2009mg oral voriconazole twice daily (for the aspergillosis). With prompt diagnosis and treatment, the patient survived these fatal fungal co-infections and finally was discharged.<\/jats:p>","DOI":"10.1099\/acmi.0.000139","type":"journal-article","created":{"date-parts":[[2020,6,17]],"date-time":"2020-06-17T16:15:21Z","timestamp":1592410521000},"source":"Crossref","is-referenced-by-count":4,"title":["A treated case of rhinocerebral zygomycosis with aspergillosis: a case report from India"],"prefix":"10.1099","volume":"2","author":[{"given":"Shalini","family":"Malhothra","sequence":"first","affiliation":[{"name":"Department of Microbiology, PGIMER and Dr Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7228-2620","authenticated-orcid":false,"given":"Sabyasachi","family":"Mandal","sequence":"additional","affiliation":[{"name":"Department of Microbiology, PGIMER and Dr Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajkumari","family":"Meena","sequence":"additional","affiliation":[{"name":"Department of Microbiology, PGIMER and Dr Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priti","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Microbiology, PGIMER and Dr Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nirmaljit Kaur","family":"Bhatia","sequence":"additional","affiliation":[{"name":"Department of Microbiology, PGIMER and Dr Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nandini","family":"Duggal","sequence":"additional","affiliation":[{"name":"Department of Microbiology, PGIMER and Dr Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"R1","first-page":"9","article-title":"Preliminary report on Aspergillus mycosis of the antrum maxillare","volume":"4","author":"Mackenzie","year":"1893","journal-title":"Johns Hopkins Hospital Bulletin"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(19)30312-3"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir864"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1470-9465.2004.00843.x"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.4314\/eamj.v79i7.8845"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.98.12030705"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1975.00780400041011"},{"key":"R8","first-page":"26","article-title":"Aspergillosis of the maxillary antrum: a case report","volume":"1","author":"Dayananda","year":"2002","journal-title":"J Oral Maxillofac Pathol"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/382473"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.4103\/1793-5482.144188"},{"key":"R11","article-title":"Rhinocerebral mucormycosis. eMedicine Journal (www.emedicine.com\/med\/topic2026.htm) (accessed 24 April 2008);","author":"Earhart","year":"2006"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-004-1263-9"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.1016\/j.idcr.2015.10.001"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.005272-0"}],"container-title":["Access Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/acmi\/10.1099\/acmi.0.000139?crawler=true&mimetype=application\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T00:22:44Z","timestamp":1702599764000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/acmi\/10.1099\/acmi.0.000139"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,1]]},"references-count":14,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,8,1]]}},"URL":"https:\/\/doi.org\/10.1099\/acmi.0.000139","relation":{},"ISSN":["2516-8290"],"issn-type":[{"value":"2516-8290","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,1]]}}}