{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:08:09Z","timestamp":1747181289477,"version":"3.40.5"},"reference-count":17,"publisher":"Microbiology Society","issue":"11","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,11,1]]},"abstract":"\n Introduction.<\/jats:bold>\n \n \n Mycobacterium mucogenicum<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> is a rare non-tuberculous organism associated with catheter-related infections when pathogenic in humans. We present the first case of an external ventricular drain (EVD)-associated \n \n M. mucogenicum<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> meningitis.<\/jats:p>\n \n Case presentation.<\/jats:bold> A 55-year-old woman had EVD placement for obstructive hydrocephalus following traumatic subarachnoid haemorrhage. Cerebrospinal fluid (CSF) was obtained 5\u2009days later for fever and neurological changes. \n \n M. mucogenicum<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> was ultimately isolated from the CSF and the patient was placed on appropriate antibiotics. Her management included replacement of the EVD and a prolonged course of anti-mycobacterial antibiotics. CSF findings showed her response to therapy and neurological exam improved after 6\u2009weeks.<\/jats:p>\n \n Conclusion.<\/jats:bold>\n \n \n M. mucogenicum<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> infections are very rare and existing reports indicate that it may be a device- or catheter-related pathogen. This microorganism has not been previously associated with an EVD. Ours may be the first documented report of EVD-related \n \n M. mucogenicum<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> infection.<\/jats:p>","DOI":"10.1099\/acmi.0.000167","type":"journal-article","created":{"date-parts":[[2020,9,3]],"date-time":"2020-09-03T15:17:45Z","timestamp":1599146265000},"source":"Crossref","is-referenced-by-count":2,"title":["Mycobacterium mucogenicum meningitis due to external ventricular drain"],"prefix":"10.1099","volume":"2","author":[{"given":"Salwa","family":"Moiz","sequence":"first","affiliation":[{"name":"Center for Aging Research, Regenstrief Institute, Indianapolis, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Rahman","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care, Indiana University School of Medicine, Indianapolis, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Morcos","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care, Indiana University School of Medicine, Indianapolis, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asma","family":"Siddiqui","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care, Indiana University School of Medicine, Indianapolis, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5364-3470","authenticated-orcid":false,"given":"Usman Bin","family":"Hameed","sequence":"additional","affiliation":[{"name":"The Aga Khan University School of Medicine, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.44.3.837-840.2006"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2009.03028.x"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/145.1.9"},{"volume-title":"Mandell, Douglas, and Bennett\u2019s Principles and Practice of Infectious Diseases","year":"2015","author":"Bennett","key":"R4"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-199812000-00014"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1086\/502341"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1043\/0003-9985(2002)126<0073:MMIFAP>2.0.CO;2"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.31.12.3231-3239.1993"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.54.12.3122-3125.1988"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-45-2-262"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2008.07.016"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.54.7.1756-1760.1988"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.43.3.722-724.1982"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.44.3.837-840.2006"},{"key":"R15","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200604-571ST"},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1309\/1KB2GKYT1BUEYLB5"},{"key":"R17","article-title":"Mycobacterium smegmatis bacteremia in an immunocompetent host IDCases","volume":"15","author":"Butt","year":"2019"}],"container-title":["Access Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/acmi\/10.1099\/acmi.0.000167?crawler=true&mimetype=application\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T05:30:52Z","timestamp":1702618252000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/acmi\/10.1099\/acmi.0.000167"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,1]]},"references-count":17,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11,1]]}},"URL":"https:\/\/doi.org\/10.1099\/acmi.0.000167","relation":{},"ISSN":["2516-8290"],"issn-type":[{"type":"electronic","value":"2516-8290"}],"subject":[],"published":{"date-parts":[[2020,11,1]]}}}