{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T01:35:32Z","timestamp":1772156132175,"version":"3.50.1"},"reference-count":15,"publisher":"Microbiology Society","issue":"4","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,1]]},"abstract":"\n Giardiasis is an infection of the small intestine caused by the protozoan parasite\n Giardia intestinalis<\/jats:italic>\n and one of the most common parasitic intestinal diseases in humans worldwide. It mainly manifests as a self-limited illness in the case of immunocompetent patients and usually does not require treatment. However, immunodeficiency is a risk factor for the onset of severe\n Giardia<\/jats:italic>\n infection. In this report, a case of recurrent giardiasis refractory to nitroimidazole therapy is presented. A 7-year-old male patient with steroid-resistant nephrotic syndrome came to our hospital because of chronic diarrhoea. The patient was on long-term immunosuppressive therapy. Microscopic examination of stool showed a significant number of trophozoites and cysts of\n G. intestinalis<\/jats:italic>\n . Treatment with metronidazole for longer duration than recommended has failed to clear the parasite in the present case.\n <\/jats:p>","DOI":"10.1099\/acmi.0.000476.v3","type":"journal-article","created":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T11:16:14Z","timestamp":1682421374000},"source":"Crossref","is-referenced-by-count":0,"title":["Refractory giardiasis in a child with steroid-resistant nephrotic syndrome"],"prefix":"10.1099","volume":"5","author":[{"given":"Jitu Mani","family":"Kalita","sequence":"first","affiliation":[{"name":"Department of Microbiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, Pin-342005, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirtika","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Microbiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, Pin-342005, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naila","family":"Mohammad","sequence":"additional","affiliation":[{"name":"Department of Microbiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, Pin-342005, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vibhor","family":"Tak","sequence":"additional","affiliation":[{"name":"Department of Microbiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, Pin-342005, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aliza","family":"Mittal","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, All India Institute of Medical Sciences, Jodhpur, Rajasthan, Pin-342005, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vijaya Lakshmi","family":"Nag","sequence":"additional","affiliation":[{"name":"Department of Microbiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, Pin-342005, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.4103\/0255-0857.142236"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1086\/320886"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2010.09-0742"},{"key":"R4","article-title":"The treatment of diarrhoea: a manual for physicians and other senior health workers, 4th rev. 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