{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:11:14Z","timestamp":1779235874796,"version":"3.51.4"},"reference-count":20,"publisher":"Microbiology Society","issue":"6","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Fundamental Grant Ministry of Education & Technology"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,6,1]]},"abstract":"\n \n \n Streptococcus pneumoniae<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n is one of the pathogenic bacteria causing invasive pneumococcal diseases such as pneumonia, sepsis, and meningitis, which are commonly reported in children and adults. In this study, we investigated the nasopharyngeal carriage rates, serotype distribution, and antimicrobial susceptibility profiles of\n \n \n S. pneumoniae<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n among children with pneumonia and healthy children under 5\u2009years old in Padang, West Sumatra, Indonesia. Nasopharyngeal swabs were collected from 65 hospitalized children with pneumonia in a referral hospital and from 65 healthy children at two day-care centers from 2018 to 2019.\n \n \n S. pneumoniae<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n was identified by conventional and molecular methods. Antibiotic susceptibility was performed with the disc diffusion method. Out of 130 children,\n \n \n S. pneumoniae<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n strains were carried by 53% and 9.2\u200a% in healthy children (35\/65) and children with pneumonia (6\/65), respectively. Serotype 19F was the most common serotype among the isolated strains (21%) followed by 6C (10%), 14, 34 (7\u200a% each), and 1, 23F, 6A, 6B (5\u200a% each). Moreover, 55\u200a% of the strains (23\/42) were covered by the 13-valent pneumococcal conjugate vaccine. Most isolates were susceptible to vancomycin (100%), chloramphenicol (93%), clindamycin (76%), erythromycin (71%), and tetracycline (69%). Serotype 19F was commonly found as a multi-drug resistant strain.\n <\/jats:p>","DOI":"10.1099\/acmi.0.000584.v3","type":"journal-article","created":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T12:16:57Z","timestamp":1686917817000},"source":"Crossref","is-referenced-by-count":5,"title":["Nasopharyngeal carriage and antimicrobial susceptibility profiles of Streptococcus pneumoniae among children with pneumonia and healthy children in Padang, Indonesia"],"prefix":"10.1099","volume":"5","author":[{"given":"Finny Fitry","family":"Yani","sequence":"first","affiliation":[{"name":"Departement of Paediatric, Dr. M. Djamil Hospital Padang, Kota Padang, Indonesia"},{"name":"Departement of Child Health, Faculty of Medicine, Universitas Andalas, Padang, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riris Juita","family":"Julianty","sequence":"additional","affiliation":[{"name":"Departement of Paediatric, Dr. M. Djamil Hospital Padang, Kota Padang, Indonesia"},{"name":"Departement of Child Health, Faculty of Medicine, Universitas Andalas, Padang, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wisnu","family":"Tafroji","sequence":"additional","affiliation":[{"name":"Eijkman Research Center for Molecular Biology, National Research and Innovation Agency (BRIN), Cibinong, West Java, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linosefa","family":"Linosefa","sequence":"additional","affiliation":[{"name":"Departement of Microbiology, Faculty of Medicine, Universitas Andalas, Padang, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Indra","family":"Ihsan","sequence":"additional","affiliation":[{"name":"Departement of Paediatric, Dr. M. Djamil Hospital Padang, Kota Padang, Indonesia"},{"name":"Departement of Child Health, Faculty of Medicine, Universitas Andalas, Padang, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nice Rachmawati","family":"Masnadi","sequence":"additional","affiliation":[{"name":"Departement of Paediatric, Dr. M. Djamil Hospital Padang, Kota Padang, Indonesia"},{"name":"Departement of Child Health, Faculty of Medicine, Universitas Andalas, Padang, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7639-7441","authenticated-orcid":false,"given":"Dodi","family":"Safari","sequence":"additional","affiliation":[{"name":"Eijkman Research Center for Molecular Biology, National Research and Innovation Agency (BRIN), Cibinong, West Java, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2019.06.001"},{"key":"R2","journal-title":"Pneumonia"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2011-200598"},{"key":"R4","article-title":"Data and Information of Indonesia Health Profile 2019 (Profil Kesehatan Indonesia Tahun 2019)","year":"2020"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-018-0001-8"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.01366"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02243-09"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1016\/j.mimet.2020.105909"},{"key":"R9","article-title":"M02-A11: Performance Standards for Antimicrobial Disk Susceptibility Tests. Approved Standard\u2014Eleventh Edition","year":"2012"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0232151"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-4254-2"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1007\/s40121-020-00330-5"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-018-1119-6"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0000000000000448"},{"key":"R15","first-page":"485","article-title":"Nasopharyngeal carriage of Streptococcus pneumoniae in healthy children under five years old in Central Lombok Regency, Indonesia","volume":"47","author":"Hadinegoro","year":"2016","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0195098"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2021.06.006"},{"key":"R18","doi-asserted-by":"publisher","DOI":"10.1099\/acmi.0.000215"},{"key":"R19","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000015942"},{"key":"R20","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10020469"}],"container-title":["Access Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/acmi\/10.1099\/acmi.0.000584.v3?crawler=true&mimetype=application\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T12:17:02Z","timestamp":1686917822000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/acmi\/10.1099\/acmi.0.000584.v3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,1]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6,1]]}},"URL":"https:\/\/doi.org\/10.1099\/acmi.0.000584.v3","relation":{"has-preprint":[{"id-type":"doi","id":"10.1099\/acmi.0.000584.v1","asserted-by":"subject"},{"id-type":"doi","id":"10.1099\/acmi.0.000584.v2","asserted-by":"subject"},{"id-type":"doi","id":"10.1099\/acmi.0.000584.v1","asserted-by":"object"},{"id-type":"doi","id":"10.1099\/acmi.0.000584.v2","asserted-by":"object"}]},"ISSN":["2516-8290"],"issn-type":[{"value":"2516-8290","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,1]]}}}