{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T01:35:48Z","timestamp":1772156148432,"version":"3.50.1"},"reference-count":9,"publisher":"Microbiology Society","issue":"12","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12,1]]},"abstract":"\n Introduction.<\/jats:bold>\n \n \n Chryseobacterium shandongense<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n is a Gram-negative\n \n \n Flavobacterium<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n bacillus with intrinsic multidrug-resistant properties.\n <\/jats:p>\n \n Case Presentation.<\/jats:bold>\n Herein, we present the first case report of human\n \n \n C. shandongense<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n infection, relating to an implantable portal and catheter (port-a-cath) central line in a 5-year-old female with cystic fibrosis. The infection was identified using a Bruker MALDI-TOF Biotyper with BDAL (v12) of blood, which was cultured due to pyrexia and rigour following port-a-cath access. This report details the effective eradication of\n \n \n C. shandongense<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n infection from the port-a-cath device using initial empirical gentamicin followed by targeted ciprofloxacin locks and systemic antibiotics.\n <\/jats:p>\n \n Conclusion.<\/jats:bold>\n We demonstrated successful eradication of\n \n \n C. shandongense<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n from a port-a-cath device, including the minimum inhibitory concentrations (MICs) required in this case. The result was eradication of central access infection, preventing progression to bacteraemia\/septicaemia and preserving central access in a child with cystic fibrosis and established respiratory disease.\n <\/jats:p>","DOI":"10.1099\/acmi.0.000700.v3","type":"journal-article","created":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T10:17:22Z","timestamp":1701771442000},"source":"Crossref","is-referenced-by-count":0,"title":["Indwelling central venous catheter infection with Chryseobacterium shandongense \u2013 successful eradication in a 5-year-old with cystic fibrosis"],"prefix":"10.1099","volume":"5","author":[{"given":"Anthony","family":"Rowan","sequence":"first","affiliation":[{"name":"Department of Paediatrics, University Hospital Limerick, Dooradoyle, Limerick, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiarnan Fallon","family":"Verbruggen","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, University Hospital Limerick, Dooradoyle, Limerick, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuala H.","family":"O'Connell","sequence":"additional","affiliation":[{"name":"School of Medicine and Centre for Interventions in Infection, Inflammation and Immunity (4i), University of Limerick, Limerick, Ireland"},{"name":"Department of Microbiology, University Hospital Limerick, Dooradoyle, Limerick, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick J.","family":"Stapleton","sequence":"additional","affiliation":[{"name":"Department of Microbiology, University Hospital Limerick, Dooradoyle, Limerick, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colum P.","family":"Dunne","sequence":"additional","affiliation":[{"name":"School of Medicine and Centre for Interventions in Infection, Inflammation and Immunity (4i), University of Limerick, Limerick, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barry","family":"Linnane","sequence":"additional","affiliation":[{"name":"School of Medicine and Centre for Interventions in Infection, Inflammation and Immunity (4i), University of Limerick, Limerick, Ireland"},{"name":"Department of Paediatrics, University Hospital Limerick, Dooradoyle, Limerick, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daryl","family":"Butler","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, University Hospital Limerick, Dooradoyle, Limerick, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.6720"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.000186"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1046\/j.1198-743x.2001.00273.x"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1016\/S1684-1182(10)60077-1"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2016.02.006"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2007.08.002"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2012.08.007"},{"key":"R8","first-page":"34","article-title":"\u201cIn vitro\u201d activity of different antimicrobial agents on Gram-negative nonfermentative bacilli, excluding Pseudomonas aeruginosa and Acinetobacter spp","volume":"37","author":"Vay","year":"2005","journal-title":"Rev Argent Microbiol"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.1.445-448.2004"}],"container-title":["Access Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/acmi\/10.1099\/acmi.0.000700.v3?crawler=true&mimetype=application\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T10:17:26Z","timestamp":1701771446000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/acmi\/10.1099\/acmi.0.000700.v3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,1]]},"references-count":9,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12,1]]}},"URL":"https:\/\/doi.org\/10.1099\/acmi.0.000700.v3","relation":{"has-preprint":[{"id-type":"doi","id":"10.1099\/acmi.0.000700.v1","asserted-by":"subject"},{"id-type":"doi","id":"10.1099\/acmi.0.000700.v2","asserted-by":"subject"},{"id-type":"doi","id":"10.1099\/acmi.0.000700.v2","asserted-by":"object"},{"id-type":"doi","id":"10.1099\/acmi.0.000700.v1","asserted-by":"object"}]},"ISSN":["2516-8290"],"issn-type":[{"value":"2516-8290","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,1]]}}}