{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T23:48:52Z","timestamp":1790639332017,"version":"4.1.0"},"reference-count":36,"publisher":"Microbiology Society","issue":"12","funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"crossref","award":["NRF-2020R1A2C3012797"],"award-info":[{"award-number":["NRF-2020R1A2C3012797"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Ministry of Science & ICT","award":["NRF-2017M3A9F3046549"],"award-info":[{"award-number":["NRF-2017M3A9F3046549"]}]},{"DOI":"10.13039\/501100003715","name":"Korea Research Institute of Bioscience and Biotechnology","doi-asserted-by":"crossref","award":["KGM5232113"],"award-info":[{"award-number":["KGM5232113"]}],"id":[{"id":"10.13039\/501100003715","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,12,6]]},"abstract":"<jats:p>Cultivation and isolation of gut bacteria are necessary for understanding their role in the intestinal ecosystem. We isolated a novel bacterium, designated strain BG01<jats:sup>T<\/jats:sup>, from the faeces of a patient with Crohn's disease. Strain BG01<jats:sup>T<\/jats:sup> was a strictly anaerobic, rod-shaped, Gram-variable and endospore-forming bacterium. Strain BG01<jats:sup>T<\/jats:sup> possessed C<jats:sub>12\u200a:\u200a0<\/jats:sub>, C<jats:sub>18\u200a:\u200a0<\/jats:sub> dimethyl aldehyde (DMA) and C<jats:sub>18\u200a:\u200a1<\/jats:sub>\n                  <jats:italic>\u2009\u03c9<\/jats:italic>9<jats:italic>c<\/jats:italic> DMA as predominant cellular fatty acids and <jats:italic>meso<\/jats:italic>-diaminopimelic acid as a diagnostic diamino acid. Strain BG01<jats:sup>T<\/jats:sup> grew at 15\u201345\u2009\u00b0C (optimum, 37\u2009\u00b0C), with 0\u20134\u200a% (w\/v) NaCl (optimum, 0\u20131\u200a%), at pH 6\u201310 (optimum, pH 7) and was resistant to bile salt, but not to ampicillin, metronidazole, vancomycin and cefoperazone. Butyrate, propionate, oxalacetate and fumarate were produced as fermentation end products from Gifu anaerobic medium broth. Strain BG01<jats:sup>T<\/jats:sup> showed 97.7\u200a% 16S rRNA gene sequence similarity, and 92.0 and 48.5\u200a% of average nucleotide identity and digital DNA\u2013DNA hybridization values, respectively, with <jats:italic>\n                     <jats:named-content content-type=\"species\">\n                        <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/doi.org\/10.1601\/nm.4128\" xlink:type=\"simple\">Anaerostipes caccae<\/jats:ext-link>\n                     <\/jats:named-content>\n                  <\/jats:italic> KCTC 15019<jats:sup>T<\/jats:sup>. Genomic analysis indicated that strain BG01<jats:sup>T<\/jats:sup> had a butyrate-producing pathway. The genomic G+C content of the strain was 43.5\u2009mol%. Results of the phenotypic, phylogenetic and genotypic analyses indicated that strain BG01<jats:sup>T<\/jats:sup> represents a novel butyrate-producing species of the genus <jats:italic>\n                     <jats:named-content content-type=\"genus\">\n                        <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/doi.org\/10.1601\/nm.4127\" xlink:type=\"simple\">Anaerostipes<\/jats:ext-link>\n                     <\/jats:named-content>\n                  <\/jats:italic>, for which the name <jats:italic>Anaerostipes hominis<\/jats:italic> sp. nov. is proposed. The type strain is BG01<jats:sup>T<\/jats:sup> (=KCTC 15617<jats:sup>T<\/jats:sup>=JCM 32275<jats:sup>T<\/jats:sup>).<\/jats:p>","DOI":"10.1099\/ijsem.0.005129","type":"journal-article","created":{"date-parts":[[2021,12,6]],"date-time":"2021-12-06T16:19:14Z","timestamp":1638807554000},"source":"Crossref","is-referenced-by-count":24,"title":["Anaerostipes hominis sp. nov., a novel butyrate-producing bacteria isolated from faeces of a patient with Crohn's disease"],"prefix":"10.1099","volume":"71","author":[{"given":"Jae-Yun","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Biology, Department of Life and Nanopharmaceutical Sciences and Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul 130-701, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woorim","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Biology, Department of Life and Nanopharmaceutical Sciences and Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul 130-701, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8168-527X","authenticated-orcid":false,"given":"Na-Ri","family":"Shin","sequence":"additional","affiliation":[{"name":"Biological Resource Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup-si, Jeollabuk-do 56212, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Wook","family":"Hyun","sequence":"additional","affiliation":[{"name":"Department of Biology, Department of Life and Nanopharmaceutical Sciences and Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul 130-701, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pil Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Biology, Department of Life and Nanopharmaceutical Sciences and Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul 130-701, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Sik","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Biology, Department of Life and Nanopharmaceutical Sciences and Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul 130-701, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"June-Young","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Biology, Department of Life and Nanopharmaceutical Sciences and Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul 130-701, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Euon Jung","family":"Tak","sequence":"additional","affiliation":[{"name":"Department of Biology, Department of Life and Nanopharmaceutical Sciences and Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul 130-701, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hojun","family":"Sung","sequence":"additional","affiliation":[{"name":"Department of Biology, Department of Life and Nanopharmaceutical Sciences and Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul 130-701, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6433-5270","authenticated-orcid":false,"given":"Jin-Woo","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Biology, Department of Life and Nanopharmaceutical Sciences and Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul 130-701, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2515"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2012.152"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2007.11.059"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0706625104"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2012-13-9-r79"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1038\/nmicrobiol.2017.4"},{"key":"R7","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.tim.2014.03.001","article-title":"Phylogeny, culturing, and metagenomics of the human gut microbiota","volume":"22","author":"Walker","year":"2014","journal-title":"Trends Microbiol"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1078\/0723-2020-00096"},{"key":"R9","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.anaerobe.2012.09.002","article-title":"Anaerostipes hadrus comb. nov., a dominant species within the human colonic microbiota; 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