{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T14:10:40Z","timestamp":1790777440704,"version":"4.1.0"},"reference-count":38,"publisher":"Microbiology Society","issue":"11","license":[{"start":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T00:00:00Z","timestamp":1700006400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,15]]},"abstract":"<jats:p>Seal finger (sealer\u2019s finger, spekk finger), an extremely painful hand infection contracted by individuals handling seals, has previously been associated with <jats:italic>Mycoplasma phocacerebrale<\/jats:italic>. From 2000 to 2014, six independent strains of a novel <jats:italic>Mycoplasma<\/jats:italic> species were isolated at Statens Serum Institut, Denmark, from Scandinavian patients with seal finger (M5725<jats:sup>T<\/jats:sup>, M6447, M6620, M6642 and M6879) or septic arthritis (M6921). Prior to the onset of infection, all patients had reported contact with unspeciated seals. All isolates grew within 2\u20135\u2009days in Friis\u2019 modified broth and metabolized glucose and arginine but not urea. Strains M5725<jats:sup>T<\/jats:sup>, M6447, M6642 and M6921 also grew in Hayflick-type media. Colonies on agar media were large (0.5\u20131.0\u2009mm) and had a typical \u2018fried egg\u2019 appearance, reduced tetrazolium, and were digitonin sensitive. Growth occurred at 32\u200a\u00b0C but not at 42\u200a\u00b0C. Strains were susceptible to doxycycline and moxifloxacin but resistant to azithromycin and erythromycin. The genomes of the six strains were sequenced and relatedness to all known <jats:italic>Mycoplasma<\/jats:italic> species was inferred. Phylogenetic analyses using 16S rRNA gene sequences and core genome single nucleotide polymorphisms showed that the isolated strains were highly similar and phylogenetically distinct from all other species within the genus <jats:italic>Mycoplasma<\/jats:italic>. The sizes of the genome sequences of the strains ranged from 744\u200a321 to 772409\u2009bp, with a G+C content of 25.0\u201325.2\u200amol%. Based on these analyses, we propose a novel species of the genus <jats:italic>Mycoplasma<\/jats:italic> with the name <jats:italic>Mycoplasma phocimorsus<\/jats:italic> sp. nov. with the first isolate M5725<jats:sup>T<\/jats:sup> (NCTC 14922<jats:sup>T<\/jats:sup>=DSM 116188<jats:sup>T<\/jats:sup>) as the proposed type strain and representative strains M6447, M6620, M6642, M6879 and M6921.<\/jats:p>","DOI":"10.1099\/ijsem.0.006163","type":"journal-article","created":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T15:16:55Z","timestamp":1700061415000},"source":"Crossref","is-referenced-by-count":12,"title":["Mycoplasma phocimorsus sp. nov., isolated from Scandinavian patients with seal finger or septic arthritis after contact with seals"],"prefix":"10.1099","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6759-2758","authenticated-orcid":false,"given":"Axel","family":"Skafte-Holm","sequence":"first","affiliation":[{"name":"Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0997-1503","authenticated-orcid":false,"given":"Thomas Roland","family":"Pedersen","sequence":"additional","affiliation":[{"name":"Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9278-9546","authenticated-orcid":false,"given":"Maria","family":"Fr\u00f8lund","sequence":"additional","affiliation":[{"name":"Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0321-1180","authenticated-orcid":false,"given":"Marc","family":"Stegger","sequence":"additional","affiliation":[{"name":"Antimicrobial Resistance and Infectious Diseases Laboratory, Harry Butler Institute, Murdoch University, Perth, Australia"},{"name":"Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8811-0260","authenticated-orcid":false,"given":"Klaus","family":"Qvortrup","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, CFIM, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dina L.","family":"Michaels","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Immunology, University of Florida, Gainesville, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel R.","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Immunology, University of Florida, Gainesville, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7464-7435","authenticated-orcid":false,"given":"Jorgen Skov","family":"Jensen","sequence":"additional","affiliation":[{"name":"Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1099\/ijsem.0.005224"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-42-2-211"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-41-1-39"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1086\/514980"},{"key":"R5","first-page":"426","article-title":"Seal finger in Denmark diagnosed by PCR-technique","volume":"174","author":"Jansen","year":"2012","journal-title":"Ugeskr Laeger"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1080\/02841850600919259"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16768-8"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ875"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.3928\/0147-7447-19910601-15"},{"key":"R10","first-page":"105","article-title":"Letter: seal finger: an unsolved medical problem in Canada","volume":"115","author":"Beck","year":"1976","journal-title":"Can Med Assoc J"},{"key":"R11","article-title":"Seal finger: occurrence in Antarctica. 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