{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T17:41:29Z","timestamp":1772646089507,"version":"3.50.1"},"reference-count":28,"publisher":"Microbiology Society","issue":"1","license":[{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Sakura Cooperation","award":["J18ZZ00082"],"award-info":[{"award-number":["J18ZZ00082"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,12]]},"abstract":"<jats:p>\n                    A facultative anaerobic, catalase-negative, lactic acid-producing, non-endospore-forming, Gram-positive coccoid bacterium, strain MT\/JULY 2010\n                    <jats:sup>T<\/jats:sup>\n                    , was isolated from the stomach of a\n                    <jats:italic>Helicobacter pylori<\/jats:italic>\n                    -positive Japanese female patient with pre-neoplastic gastric mucosa. This bacterium can form clusters, chains or pairs or occurs singly in liquid media. The growth ranges for temperature, pH and NaCl concentration were 20\u201345\u2009\u00b0C, pH 5.0\u20137.0 and 1\u20134%, respectively. Cells exhibited an unusual tumbling motion when observed under the microscope using a hanging drop assay. Observation under an electron microscope showed some unidentified structures and numerous fimbriae-like appendages. The combined results of 16S rRNA gene sequence analysis and the overall genome-related index [average nucleotide identity (ANI) and digital DNA\u2013DNA hybridization (dDDH)] classified the bacterium as a novel species of the genus\n                    <jats:italic>Streptococcus<\/jats:italic>\n                    . It forms a monophyletic cluster with\n                    <jats:italic>Streptococcus parasanguinis<\/jats:italic>\n                    ATCC 15912\n                    <jats:sup>T<\/jats:sup>\n                    in the phylogenetic tree with 94.4% ANI. Furthermore, the conventional DNA\u2013DNA hybridization assay and dDDH of the two strains identified their relatedness as 62.5% and 58.7% (both below the 70% threshold), respectively. The DNA G+C content, determined by nuclease P1-digested genomic DNA, was 42.6\u2009mol%, while the digital G+C content calculated\n                    <jats:italic>in silico<\/jats:italic>\n                    was 41.8 mol%. Based on the phenotypic and genotypic results, strain MT\/JULY 2010\n                    <jats:sup>T<\/jats:sup>\n                    represents a novel species within the genus. The name\n                    <jats:italic>Streptococcus mobilis<\/jats:italic>\n                    sp. nov. is proposed. The type strain is MT\/JULY 2010\n                    <jats:sup>T<\/jats:sup>\n                    (=ATCC BAA-2258\n                    <jats:sup>T<\/jats:sup>\n                    =NBRC 107862\n                    <jats:sup>T<\/jats:sup>\n                    =NCBI 948105\n                    <jats:sup>T<\/jats:sup>\n                    =V10\/022878\n                    <jats:sup>T<\/jats:sup>\n                    ).\n                  <\/jats:p>","DOI":"10.1099\/ijsem.0.007016","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T16:16:45Z","timestamp":1768234605000},"source":"Crossref","is-referenced-by-count":0,"title":["Streptococcus mobilis sp. nov., isolated from a Helicobacter pylori-positive pre-neoplastic human stomach"],"prefix":"10.1099","volume":"76","author":[{"given":"Takayuki","family":"Okada","sequence":"first","affiliation":[{"name":"Okada Medical Clinic, Suite 64, Level 6, 101 Wickham Terrace, Brisbane, Queensland, 4000, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharda Prasad","family":"Awasthi","sequence":"additional","affiliation":[{"name":"Asian Health Science Research Institute, Osaka Metropolitan University, Osaka, Japan"},{"name":"Osaka International Research Center for Infectious Diseases, Osaka Metropolitan University, Osaka, Japan"},{"name":"Graduate School of Veterinary Science, Osaka Metropolitan University, Osaka, Japan"},{"name":"Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Hinenoya","sequence":"additional","affiliation":[{"name":"Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, Japan"},{"name":"Graduate School of Veterinary Science, Osaka Metropolitan University, Osaka, Japan"},{"name":"Asian Health Science Research Institute, Osaka Metropolitan University, Osaka, Japan"},{"name":"Osaka International Research Center for Infectious Diseases, Osaka Metropolitan University, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noritoshi","family":"Hatanaka","sequence":"additional","affiliation":[{"name":"Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, Japan"},{"name":"Osaka International Research Center for Infectious Diseases, Osaka Metropolitan University, Osaka, Japan"},{"name":"Graduate School of Veterinary Science, Osaka Metropolitan University, Osaka, Japan"},{"name":"Asian Health Science Research Institute, Osaka Metropolitan University, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shota","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Research Institute for Microbial Diseases, Osaka University, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Motooka","sequence":"additional","affiliation":[{"name":"Research Institute for Microbial Diseases, Osaka University, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9063-2201","authenticated-orcid":false,"given":"Shinji","family":"Yamasaki","sequence":"additional","affiliation":[{"name":"Asian Health Science Research Institute, Osaka Metropolitan University, Osaka, Japan"},{"name":"Graduate School of Veterinary Science, Osaka Metropolitan University, Osaka, Japan"},{"name":"Osaka International Research Center for Infectious Diseases, Osaka Metropolitan University, Osaka, Japan"},{"name":"Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"R1","volume-title":"Streptococcus Pyogenes: Basic Biology to Clinical Manifestations","author":"Ferretti","year":"2016"},{"key":"R2","first-page":"655","volume-title":"Bergey\u2019s Manual of Systematic Bacteriology. 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