{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:56:24Z","timestamp":1786118184492,"version":"build-2736575974"},"reference-count":29,"publisher":"Microbiology Society","issue":"8","funder":[{"name":"Prevention and Control of Emerging and Major Infectious Diseases-National Science and Technology Major Project","award":["2025ZD01900100"],"award-info":[{"award-number":["2025ZD01900100"]}]},{"DOI":"10.13039\/100017949","name":"Health Commission of Shanxi Province","doi-asserted-by":"crossref","award":["Grant No. 2024149"],"award-info":[{"award-number":["Grant No. 2024149"]}],"id":[{"id":"10.13039\/100017949","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Young Top-notch Talent Project in the Medical and Health Field of the Sanjin Talents Program","award":["Grant No. SJYC2024469"],"award-info":[{"award-number":["Grant No. SJYC2024469"]}]},{"name":"Youth Fund for Enhancing Capability of Infectious Disease Surveillance and Prevention","award":["Grant No. 102393240020020000003"],"award-info":[{"award-number":["Grant No. 102393240020020000003"]}]},{"name":"Shanxi Provincial Basic Research Program Youth Project","award":["Grant No. 202503021212162"],"award-info":[{"award-number":["Grant No. 202503021212162"]}]},{"name":"Major Project of Guangzhou National Laboratory","award":["Grant No. GZNL2024A01025"],"award-info":[{"award-number":["Grant No. GZNL2024A01025"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,5]]},"abstract":"<jats:p>\n                    Two Gram-stain-positive, catalase-positive, oxidase-negative, non-spore-forming, aerotolerant anaerobic and non-motile short rod-shaped bacterial strains, designated V947\n                    <jats:sup>T<\/jats:sup>\n                    and V970, were isolated from nasal swab samples of coal miners. Phylogenetic analyses based on 16S rRNA gene sequences and whole-genome sequences revealed that strains V947\n                    <jats:sup>T<\/jats:sup>\n                    and V970 represent a distinct lineage within the genus\n                    <jats:italic>Cutibacterium<\/jats:italic>\n                    , most closely related to\n                    <jats:italic>Cutibacterium avidum<\/jats:italic>\n                    ATCC 25577\n                    <jats:sup>T<\/jats:sup>\n                    (16S rRNA gene sequence similarity of 97.09%). Whole-genome comparative analyses showed that the average nucleotide identity values between the two strains and all validly published species of the genus\n                    <jats:italic>Cutibacterium<\/jats:italic>\n                    with correct nomenclature ranged from 76.55 to 90.26%, while the digital DNA\u2013DNA hybridization values ranged from 21.80 to 40.40%, both of which are well below the accepted thresholds for species delineation. Pangenome analysis identified 711 species-specific gene clusters present in strains V947\n                    <jats:sup>T<\/jats:sup>\n                    and V970 but absent from all reference type strains of the genus, which were predominantly involved in carbohydrate transport and metabolism, inorganic ion transport and signal transduction mechanisms, suggesting distinct metabolic capabilities and potential for environmental adaptation. These genomic features not only support the delineation of a novel species but also expand the known genomic and functional diversity within the genus\n                    <jats:italic>Cutibacterium<\/jats:italic>\n                    . The predominant cellular fatty acids were iso-C\n                    <jats:sub>15:0<\/jats:sub>\n                    and anteiso-C\n                    <jats:sub>15:0<\/jats:sub>\n                    . The major polar lipids of strain V947\n                    <jats:sup>T<\/jats:sup>\n                    were diphosphatidylglycerol, phosphatidylinositol and phosphatidylcholine, and the predominant menaquinones were MK-8(H\n                    <jats:sub>4<\/jats:sub>\n                    ) and MK-9(H\n                    <jats:sub>6<\/jats:sub>\n                    ). On the basis of phylogenetic, genomic, chemotaxonomic and phenotypic characteristics, strains V947\n                    <jats:sup>T<\/jats:sup>\n                    and V970 represent a novel species of the genus\n                    <jats:italic>Cutibacterium<\/jats:italic>\n                    , for which the name\n                    <jats:italic>Cutibacterium nasicola<\/jats:italic>\n                    sp. nov. is proposed. The type strain is V947\n                    <jats:sup>T<\/jats:sup>\n                    (=CGMCC 1.5844\n                    <jats:sup>T<\/jats:sup>\n                    =KCTC 59608\n                    <jats:sup>T<\/jats:sup>\n                    ).\n                  <\/jats:p>","DOI":"10.1099\/ijsem.0.007267","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T15:16:40Z","timestamp":1786029400000},"source":"Crossref","is-referenced-by-count":0,"title":["Cutibacterium nasicola sp. nov., isolated from nasal swabs of coal miners"],"prefix":"10.1099","volume":"76","author":[{"given":"Junyao","family":"Xie","sequence":"first","affiliation":[{"name":"Key Laboratory of Coal Environmental Pathogenicity and Prevention, Shanxi Medical University, Ministry of Education, Taiyuan, Shanxi 030001, PR China"},{"name":"Research Center for Reverse Microbial Etiology, Workstation of Academician, School of Public Health, Shanxi Medical University, Taiyuan 030001, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Liu","sequence":"additional","affiliation":[{"name":"Research Center for Reverse Microbial Etiology, Workstation of Academician, School of Public Health, Shanxi Medical University, Taiyuan 030001, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Research Center for Reverse Microbial Etiology, Workstation of Academician, School of Public Health, Shanxi Medical University, Taiyuan 030001, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangyu","family":"Gao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Coal Environmental Pathogenicity and Prevention, Shanxi Medical University, Ministry of Education, Taiyuan, Shanxi 030001, PR China"},{"name":"Research Center for Reverse Microbial Etiology, Workstation of Academician, School of Public Health, Shanxi Medical University, Taiyuan 030001, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijun","family":"Zhao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Coal Environmental Pathogenicity and Prevention, Shanxi Medical University, Ministry of Education, Taiyuan, Shanxi 030001, PR China"},{"name":"Research Center for Reverse Microbial Etiology, Workstation of Academician, School of Public Health, Shanxi Medical University, Taiyuan 030001, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taoyu","family":"Yan","sequence":"additional","affiliation":[{"name":"Key Laboratory of Coal Environmental Pathogenicity and Prevention, Shanxi Medical University, Ministry of Education, Taiyuan, Shanxi 030001, PR China"},{"name":"Research Center for Reverse Microbial Etiology, Workstation of Academician, School of Public Health, Shanxi Medical University, Taiyuan 030001, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zixin","family":"Weng","sequence":"additional","affiliation":[{"name":"Research Center for Reverse Microbial Etiology, Workstation of Academician, School of Public Health, Shanxi Medical University, Taiyuan 030001, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Yang","sequence":"additional","affiliation":[{"name":"Research Center for Reverse Microbial Etiology, Workstation of Academician, School of Public Health, Shanxi Medical University, Taiyuan 030001, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caixin","family":"Yang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Coal Environmental Pathogenicity and Prevention, Shanxi Medical University, Ministry of Education, Taiyuan, Shanxi 030001, PR China"},{"name":"Research Center for Reverse Microbial Etiology, Workstation of Academician, School of Public Health, Shanxi Medical University, Taiyuan 030001, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiming","family":"Kang","sequence":"additional","affiliation":[{"name":"Ophthalmic Microbiology Laboratory, Shanxi Province Key Laboratory of Ophthalmology, Shanxi Eye Hospital, Taiyuan, Shanxi 030001, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji","family":"Pu","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, PR China"},{"name":"Research Center for Reverse Microbial Etiology, Workstation of Academician, School of Public Health, Shanxi Medical University, Taiyuan 030001, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Zheng","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, PR China"},{"name":"Research Center for Reverse Microbial Etiology, Workstation of Academician, School of Public Health, Shanxi Medical University, Taiyuan 030001, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiwei","family":"Shi","sequence":"additional","affiliation":[{"name":"The First Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianguo","family":"Xu","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, PR China"},{"name":"Research Center for Reverse Microbial Etiology, Workstation of Academician, School of Public Health, Shanxi Medical University, Taiyuan 030001, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kui","family":"Dong","sequence":"additional","affiliation":[{"name":"Ophthalmic Microbiology Laboratory, Shanxi Province Key Laboratory of Ophthalmology, Shanxi Eye Hospital, Taiyuan, Shanxi 030001, PR China"},{"name":"Key Laboratory of Coal Environmental Pathogenicity and Prevention, Shanxi Medical University, Ministry of Education, Taiyuan, Shanxi 030001, PR China"},{"name":"Research Center for Reverse Microbial Etiology, Workstation of Academician, School of Public Health, Shanxi Medical University, Taiyuan 030001, PR China"},{"name":"National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1099\/ijsem.0.006099"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms9020303"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-14-640"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2021.673845"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.00515-25"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2007.06.012"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01435-16"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1099\/ijsem.0.001367"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00064-17"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.12.5463"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1099\/ijsem.0.006421"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/22.22.4673"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.1007\/BF01734359"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msy096"},{"key":"R15","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.molbev.a040454"},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3238"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu077"},{"key":"R18","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-023-01940-w"},{"key":"R19","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btl158"},{"key":"R20","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/mst010"},{"key":"R21","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msp077"},{"key":"R22","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkad359"},{"key":"R23","doi-asserted-by":"publisher","DOI":"10.1007\/s10482-017-0844-4"},{"key":"R24","doi-asserted-by":"publisher","DOI":"10.4056\/sigs.531120"},{"key":"R25","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.64483-0"},{"key":"R26","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btv421"},{"key":"R27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2672.1985.tb01491.x"},{"key":"R28","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-27-2-104"},{"key":"R29","doi-asserted-by":"publisher","DOI":"10.1128\/mr.45.2.316-354.1981"}],"container-title":["International Journal of Systematic and Evolutionary Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/ijsem\/10.1099\/ijsem.0.007267?crawler=true&mimetype=application\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T15:16:41Z","timestamp":1786029401000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/ijsem\/10.1099\/ijsem.0.007267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,5]]},"references-count":29,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8,5]]}},"URL":"https:\/\/doi.org\/10.1099\/ijsem.0.007267","relation":{},"ISSN":["1466-5026","1466-5034"],"issn-type":[{"value":"1466-5026","type":"print"},{"value":"1466-5034","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,5]]}}}