{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T17:05:04Z","timestamp":1790010304873,"version":"4.0.1"},"reference-count":56,"publisher":"Microbiology Society","issue":"9","funder":[{"name":"Yantai Science and Technology Development Project","award":["2022XDRH027"],"award-info":[{"award-number":["2022XDRH027"]}]},{"name":"Yantai Science and Technology Development Project","award":["2022JCYJ024"],"award-info":[{"award-number":["2022JCYJ024"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,21]]},"abstract":"<jats:p>\n                    A Gram-staining positive, greenish-yellow, immotile, catalase-positive, oxidase-negative actinobacterium, designated strain G70\n                    <jats:sup>T<\/jats:sup>\n                    , was isolated from the marine sediment in the Bohai Sea, China. The results of phylogenetic analysis based on the 16S rRNA gene sequences indicated that the strain G70\n                    <jats:sup>T<\/jats:sup>\n                    belongs to the genus\n                    <jats:italic>Isoptericola<\/jats:italic>\n                    , revealing 99.1% similarity to\n                    <jats:italic>Isoptericola halotolerans<\/jats:italic>\n                    YIM 70177\n                    <jats:sup>T<\/jats:sup>\n                    , 98.7% similarity to\n                    <jats:italic>Isoptericola chiayiensis<\/jats:italic>\n                    06182\u2009M-1\n                    <jats:sup>T<\/jats:sup>\n                    and 98.2% similarity to\n                    <jats:italic>Isoptericola salitolerans<\/jats:italic>\n                    TRM F109\n                    <jats:sup>T<\/jats:sup>\n                    . Strain G70\n                    <jats:sup>T<\/jats:sup>\n                    grew at 4\u201345\u2009\u00b0C (optimum 30\u2009\u00b0C), pH 6\u201313 (optimum 8\u20139) and 0\u201325% (wt\/v) NaCl (optimum 1%). The genome size of strain G70\n                    <jats:sup>T<\/jats:sup>\n                    was 3.59\u2009Mb, with DNA G+C content of 72.6 mol%. Average nucleotide identities between strain G70\n                    <jats:sup>T<\/jats:sup>\n                    and\n                    <jats:italic>I. halotolerans<\/jats:italic>\n                    YIM 70177\n                    <jats:sup>T<\/jats:sup>\n                    and\n                    <jats:italic>I. chiayiensis<\/jats:italic>\n                    06182\u2009M-1\n                    <jats:sup>T<\/jats:sup>\n                    were 83.6 and 80.7%, respectively. The digital DNA\u2013DNA hybridization values among\n                    <jats:italic>I. halotolerans<\/jats:italic>\n                    YIM 70177\n                    <jats:sup>T<\/jats:sup>\n                    and\n                    <jats:italic>I. chiayiensis<\/jats:italic>\n                    06182\u2009M-1\n                    <jats:sup>T<\/jats:sup>\n                    are 26.5 and 23.0%, respectively. The predominant fatty acids (&gt;10%) of strain G70\n                    <jats:sup>T<\/jats:sup>\n                    were anteiso-C\n                    <jats:sub>15\u200a:\u200a0<\/jats:sub>\n                    and C\n                    <jats:sub>16\u200a:\u200a0<\/jats:sub>\n                    , and the respiratory quinones were MK-9 (H\n                    <jats:sub>4<\/jats:sub>\n                    ), MK-9 (H\n                    <jats:sub>2<\/jats:sub>\n                    ) and MK-9. The polar lipids were identified as diphosphatidylglycerol, phosphatidylglycerol, phosphatidylinositol, an unknown phosphoglycolipid and an unknown phospholipid. Strain G70\n                    <jats:sup>T<\/jats:sup>\n                    showed significant broad-spectrum antimicrobial activity against both Gram-staining-negative and Gram-staining-positive bacteria and fungi. Based on all these phenotypic, genotypic and phylogenetic results, strain G70\n                    <jats:sup>T<\/jats:sup>\n                    was distinguished from other species with validly published names in the genus\n                    <jats:italic>Isoptericola<\/jats:italic>\n                    and should be classified as representing a novel species, for which the name\n                    <jats:italic>Isoptericola maris<\/jats:italic>\n                    sp. nov. was proposed. The type strain is G70\n                    <jats:sup>T<\/jats:sup>\n                    (MCCC 1K08870\n                    <jats:sup>T<\/jats:sup>\n                    =KCTC 59000\n                    <jats:sup>T<\/jats:sup>\n                    ).\n                  <\/jats:p>","DOI":"10.1099\/ijsem.0.007291","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:16:14Z","timestamp":1790007374000},"source":"Crossref","is-referenced-by-count":0,"title":["Isoptericola maris sp. nov., a novel actinobacterium isolated from the marine sediment in the Bohai Sea, China"],"prefix":"10.1099","volume":"76","author":[{"given":"Ruixue","family":"Jia","sequence":"first","affiliation":[{"name":"Academy of Pharmacy, Xian-Jiaotong Liverpool University, Suzhou 215000, PR China"},{"name":"School of Pharmacy, Binzhou Medical University, Yantai 264003, PR 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