{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:08:20Z","timestamp":1791295700544,"version":"4.1.0"},"reference-count":44,"publisher":"Microbiology Society","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,12,16]]},"DOI":"10.1099\/jgv.0.000648","type":"journal-article","created":{"date-parts":[[2016,10,28]],"date-time":"2016-10-28T22:12:22Z","timestamp":1477692742000},"page":"3193-3204","source":"Crossref","is-referenced-by-count":16,"title":["Progressive glycosylation of the haemagglutinin of avian influenza H5N1 modulates virus replication, virulence and chicken-to-chicken transmission without significant impact on antigenic drift"],"prefix":"10.1099","volume":"97","author":[{"given":"El-Sayed M.","family":"Abdelwhab","sequence":"first","affiliation":[{"name":"National Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Dokki, Giza 12618, Egypt"},{"name":"Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, S\u00fcdufer 10, 17493 Greifswald-Insel Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jutta","family":"Veits","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, S\u00fcdufer 10, 17493 Greifswald-Insel Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerstin","family":"Tauscher","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, S\u00fcdufer 10, 17493 Greifswald-Insel Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Ziller","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, S\u00fcdufer 10, 17493 Greifswald-Insel Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Grund","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, S\u00fcdufer 10, 17493 Greifswald-Insel Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed K.","family":"Hassan","sequence":"additional","affiliation":[{"name":"National Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Dokki, Giza 12618, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Momtaz","family":"Shaheen","sequence":"additional","affiliation":[{"name":"National Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Dokki, Giza 12618, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timm C.","family":"Harder","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, S\u00fcdufer 10, 17493 Greifswald-Insel Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Teifke","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, S\u00fcdufer 10, 17493 Greifswald-Insel Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Stech","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, S\u00fcdufer 10, 17493 Greifswald-Insel Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas C.","family":"Mettenleiter","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, S\u00fcdufer 10, 17493 Greifswald-Insel Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.06.090"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1007\/s11262-012-0758-1"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2016.02.023"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-012-1385-9"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-1702(01)00272-6"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1177\/0300985810386467"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02403-10"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2007.04.017"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1108754108"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1016\/S1672-0229(08)60032-7"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.01.006"},{"key":"R12","first-page":"95","article-title":"BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95\/98\/NT","volume":"41","author":"Hall","year":"1999","journal-title":"Nucleic Acids Symp Ser"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.139.3.613"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1007\/s007050170002"},{"key":"R15","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.18.9954-9964.2004"},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2012.08.001"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-62703-646-7_8"},{"key":"R18","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2012.53.5.886"},{"key":"R19","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-1702(01)00389-6"},{"key":"R20","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2012.11.033"},{"key":"R21","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1128\/JVI.73.2.1146-1155.1999","article-title":"The surface glycoproteins of H5 influenza viruses isolated from humans, chickens, and wild aquatic birds have distinguishable properties","volume":"73","author":"Matrosovich","year":"1999","journal-title":"J Virol"},{"key":"R22","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01987-08"},{"key":"R23","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.19.12416-12424.2005"},{"key":"R24","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.13.6015-6020.2000"},{"key":"R25","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msu300"},{"key":"R26","article-title":"Chapter 2.3.4. \u2014 Avian influenza","year":"2015"},{"key":"R27","doi-asserted-by":"crossref","first-page":"8377","DOI":"10.1128\/JVI.71.11.8377-8384.1997","article-title":"Regulation of receptor binding affinity of influenza virus hemagglutinin by its carbohydrate moiety","volume":"71","author":"Ohuchi","year":"1997a","journal-title":"J Virol"},{"key":"R28","doi-asserted-by":"crossref","first-page":"3719","DOI":"10.1128\/JVI.71.5.3719-3725.1997","article-title":"Oligosaccharides in the stem region maintain the influenza virus hemagglutinin in the metastable form required for fusion activity","volume":"71","author":"Ohuchi","year":"1997b","journal-title":"J Virol"},{"key":"R29","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01217-07"},{"key":"R30","doi-asserted-by":"crossref","first-page":"2831","DOI":"10.1002\/j.1460-2075.1986.tb04576.x","article-title":"Mutations blocking the transport of the influenza virus hemagglutinin between the rough endoplasmic reticulum and the Golgi apparatus","volume":"5","author":"Schuy","year":"1986","journal-title":"EMBO J"},{"key":"R31","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkn646"},{"key":"R32","doi-asserted-by":"crossref","first-page":"839","DOI":"10.20506\/rst.30.3.2081","article-title":"Assessment of national strategies for control of high-pathogenicity avian influenza and low-pathogenicity notifiable avian influenza in poultry, with emphasis on vaccines and vaccination","volume":"30","author":"Swayne","year":"2011","journal-title":"Rev Sci Tech"},{"key":"R33","doi-asserted-by":"publisher","DOI":"10.3390\/v6031294"},{"key":"R34","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkh155"},{"key":"R36","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.14.6316-6323.2000"},{"key":"R37","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-83-3-601"},{"key":"R38","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0909696106"},{"key":"R39","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(86)90118-2"},{"key":"R40","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.12462"},{"key":"R35","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12230"},{"key":"R41","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0811052106"},{"key":"R43","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2014.12.011"},{"key":"R44","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.000082"},{"key":"R42","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0061397"}],"container-title":["Journal of General Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jgv\/10.1099\/jgv.0.000648?crawler=true","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,27]],"date-time":"2020-09-27T01:13:23Z","timestamp":1601169203000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jgv\/10.1099\/jgv.0.000648"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,16]]},"references-count":44,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12,16]]}},"URL":"https:\/\/doi.org\/10.1099\/jgv.0.000648","relation":{},"ISSN":["0022-1317","1465-2099"],"issn-type":[{"value":"0022-1317","type":"print"},{"value":"1465-2099","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,16]]}}}