{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T04:48:43Z","timestamp":1791521323029,"version":"4.3.4"},"reference-count":8,"publisher":"Microbiology Society","issue":"11","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,11,1]]},"abstract":"<jats:p>The family <jats:italic>Hepeviridae<\/jats:italic> includes enterically transmitted small non-enveloped positive-sense RNA viruses. It includes the genera <jats:italic>Piscihepevirus<\/jats:italic>, whose members infect fish, and <jats:italic>Orthohepevirus<\/jats:italic>, whose members infect mammals and birds. Members of the genus <jats:italic>Orthohepevirus<\/jats:italic> include hepatitis E virus, which is responsible for self-limiting acute hepatitis in humans and several mammalian species; the infection may become chronic in immunocompromised individuals. Extrahepatic manifestations of Guillain\u2013Barr\u00e9 syndrome, neuralgic amyotrophy, glomerulonephritis and pancreatitis have been described in humans. Avian hepatitis E virus causes hepatitis\u2013splenomegaly syndrome in chickens. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the taxonomy of the <jats:italic>Hepeviridae<\/jats:italic>, which is available at <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"www.ictv.global\/report\/hepeviridae\">www.ictv.global\/report\/hepeviridae.<\/jats:ext-link>\n               <\/jats:p>","DOI":"10.1099\/jgv.0.000940","type":"journal-article","created":{"date-parts":[[2017,10,12]],"date-time":"2017-10-12T14:12:42Z","timestamp":1507817562000},"page":"2645-2646","source":"Crossref","is-referenced-by-count":256,"title":["ICTV Virus Taxonomy Profile: Hepeviridae"],"prefix":"10.1099","volume":"98","author":[{"given":"Michael A.","family":"Purdy","sequence":"first","affiliation":[{"name":"Division of Viral Hepatitis, Centers for Disease Control and Prevention, MS-A33, 1600 Clifton Rd NE, Atlanta, GA 30329, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim J.","family":"Harrison","sequence":"additional","affiliation":[{"name":"University College London, Gower St, Bloomsbury, London, WC1E 6BT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Jameel","sequence":"additional","affiliation":[{"name":"Wellcome Trust\/DBT India Alliance, 1110 DLF Tower B, Jasola, New Delhi 110025, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X-J.","family":"Meng","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Division of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Tochigi-ken, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. 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