{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T04:11:34Z","timestamp":1790395894378,"version":"4.1.0"},"reference-count":150,"publisher":"Microbiology Society","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,4,1]]},"DOI":"10.1099\/jmm.0.000706","type":"journal-article","created":{"date-parts":[[2018,2,27]],"date-time":"2018-02-27T14:27:37Z","timestamp":1519741657000},"page":"466-480","source":"Crossref","is-referenced-by-count":73,"title":["Laboratory challenges in the diagnosis of hepatitis E virus"],"prefix":"10.1099","volume":"67","author":[{"given":"Duaa W.","family":"Al-Sadeq","sequence":"first","affiliation":[{"name":"Department of Biomedical Science, College of Health Sciences, Qatar University, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amin F.","family":"Majdalawieh","sequence":"additional","affiliation":[{"name":"Department of Biology, Chemistry and Environmental Sciences, College of Arts and Sciences, American University of Sharjah, Sharjah, UAE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Areej G.","family":"Mesleh","sequence":"additional","affiliation":[{"name":"Department of Biomedical Science, College of Health Sciences, Qatar University, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omnya M.","family":"Abdalla","sequence":"additional","affiliation":[{"name":"Department of Biomedical Science, College of Health Sciences, Qatar University, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gheyath K.","family":"Nasrallah","sequence":"additional","affiliation":[{"name":"Department of Biomedical Science, College of Health Sciences, Qatar University, Doha, Qatar"},{"name":"Biomedical Research Center, Qatar University, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","article-title":"Hepatitis E"},{"key":"R2","article-title":"Viral Hepatitis \u2013 Hepatitis E Information"},{"key":"R3","article-title":"Regional strategy for the prevention and control of viral hepatitis","year":"2013"},{"key":"R4","year":"2016"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.81545-0"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.12.4576-4580.2002"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03727.x"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.2006.00111.x"},{"key":"R9","first-page":"581","article-title":"Investigation of hepatitis E outbreak among refugees \u2013 Upper Nile, South Sudan, 2012\u20132013","volume":"62","year":"2013","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"R10","article-title":"Uganda: Hepatitis E Virus disease outbreak DREF Operation n\u00b0 MDRUG036-Emergency Plan of Action (EPoA) Final Report","year":"2014"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1086\/651077"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(92)90230-M"},{"key":"R13","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0168-1702(93)90024-H","article-title":"The sequence of hepatitis E virus isolated directly from a single source during an outbreak in China","volume":"28","author":"Bi","year":"1993","journal-title":"Virus Res"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.epirev.a017994"},{"key":"R15","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00057-13"},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1038\/emi.2012.7"},{"key":"R17","article-title":"Presence of hepatitis E virus (HEV) and markers for HEV infection in production swine, human patients with unexplained hepatitis, and veterinarians in Finland. Dissertationes Schola Doctoralis Scientiae Circumiectalis, Alimentarie, Biologicae","author":"Kantala","year":"2017"},{"key":"R18","doi-asserted-by":"publisher","DOI":"10.3201\/eid2006.140140"},{"key":"R19","doi-asserted-by":"publisher","DOI":"10.3201\/eid2207.160168"},{"key":"R20","doi-asserted-by":"publisher","DOI":"10.3201\/eid2212.160979"},{"key":"R21","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2012.187"},{"key":"R22","doi-asserted-by":"publisher","DOI":"10.14218\/JCTH.2016.00013"},{"key":"R23","doi-asserted-by":"publisher","DOI":"10.14218\/JCTH.2014.00006"},{"key":"R24","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu742"},{"key":"R25","first-page":"70","article-title":"Association of severity of hepatitis E virus infection in the mother and vertically transmitted infection in the fetus","volume":"13","author":"Khuroo","year":"2006","journal-title":"JK Pract"},{"key":"R26"},{"key":"R27","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13309"},{"key":"R28","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3148.2006.00652.x"},{"key":"R29","doi-asserted-by":"publisher","DOI":"10.3201\/eid1304.061387"},{"key":"R30","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2004.03437.x"},{"key":"R31","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2008.01722.x"},{"key":"R32","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2004.03300.x"},{"key":"R33","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.20215"},{"key":"R34","doi-asserted-by":"publisher","DOI":"10.1111\/j.1872-034X.2007.00024.x"},{"key":"R35","article-title":"Recommendations from the expert advisory committee on the Safety of Blood, Tissues and Organs (SaBTO) on measures to protect patients from acquiring hepatitis E virus via transfusion or transplantation","year":"2016"},{"key":"R36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2007.12.008"},{"key":"R37","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60072-6"},{"key":"R38","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03578-13"},{"key":"R39","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2013.07.019"},{"key":"R40","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61034-5"},{"key":"R41","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.39.3.918-923.2001"},{"key":"R42","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.6.3429-3437.2005"},{"key":"R43","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01419"},{"key":"R44","doi-asserted-by":"publisher","DOI":"10.1080\/17474124.2016.1185362"},{"key":"R45","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.20717"},{"key":"R46","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-008-0179-6"},{"key":"R47","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02737-9"},{"key":"R48","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2015.08.034"},{"key":"R49","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2016.03.019"},{"key":"R50","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-12-142"},{"key":"R51","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.15-0159"},{"key":"R52","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2013.06.013"},{"key":"R53","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.21656"},{"key":"R54","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.24251"},{"key":"R55","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2013.10.010"},{"key":"R56","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2013.10.003"},{"key":"R57","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0062980"},{"key":"R58","doi-asserted-by":"publisher","DOI":"10.1007\/s00430-017-0503-4"},{"key":"R59","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890360403"},{"key":"R60","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00312-06"},{"key":"R61","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-008-0657-4"},{"key":"R62","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.1.49-56.2005"},{"key":"R63","doi-asserted-by":"crossref","first-page":"7067","DOI":"10.1128\/JVI.68.11.7067-7074.1994","article-title":"Artificial mosaic protein containing antigenic epitopes of hepatitis E virus","volume":"68","author":"Khudyakov","year":"1994","journal-title":"J Virol"},{"key":"R64","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510270331"},{"key":"R65","doi-asserted-by":"crossref","first-page":"3915","DOI":"10.1128\/JCM.38.11.3915-3918.2000","article-title":"Diagnostic value of immunoglobulin G (IgG) and IgM anti-hepatitis E virus (HEV) tests based on HEV RNA in an area where hepatitis E is not endemic","volume":"38","author":"Lin","year":"2000","journal-title":"J Clin Microbiol"},{"key":"R66","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/9647675"},{"key":"R67","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.23827"},{"key":"R68","article-title":"recomLine HEV IgG\/IgM"},{"key":"R69","doi-asserted-by":"publisher","DOI":"10.1128\/CDLI.12.5.593-598.2005"},{"key":"R70","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00438-08"},{"key":"R71","doi-asserted-by":"crossref","first-page":"942","DOI":"10.4269\/ajtmh.2005.73.942","article-title":"Evaluation of a new rapid immunochromatographic assay for serodiagnosis of acute hepatitis E infection","volume":"73","author":"Myint","year":"2005","journal-title":"Am J Trop Med Hyg"},{"key":"R72","doi-asserted-by":"publisher","DOI":"10.3390\/v8080232"},{"key":"R73","doi-asserted-by":"publisher","DOI":"10.1128\/CDLI.10.4.579-586.2003"},{"key":"R74","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis688"},{"key":"R75","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.24741"},{"key":"R76","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2012.09.010"},{"key":"R77","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2257.2000.00265.x"},{"key":"R78","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61187-9"},{"key":"R79","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.899261"},{"key":"R80","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)91507-5"},{"key":"R81","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14116"},{"key":"R82","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01119-12"},{"key":"R83","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0119576"},{"key":"R84","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiw161"},{"key":"R85","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21958"},{"key":"R86","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e318296c9f7"},{"key":"R87","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2008.01910.x"},{"key":"R88","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01466-09"},{"key":"R89","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12285"},{"key":"R90","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.2009.01211.x"},{"key":"R91","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.2011.01554.x"},{"key":"R92","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.2011.01583.x"},{"key":"R93","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12056"},{"key":"R94","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.2012.01638.x"},{"key":"R95","doi-asserted-by":"publisher","DOI":"10.3201\/eid2011.140516"},{"key":"R96","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12929"},{"key":"R97","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-0934(03)00215-5"},{"key":"R98","doi-asserted-by":"publisher","DOI":"10.1590\/S1678-91992011000300003"},{"key":"R99","doi-asserted-by":"publisher","DOI":"10.2165\/00066982-200005010-00007"},{"key":"R100","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-7963(94)70117-6"},{"key":"R101","doi-asserted-by":"publisher","DOI":"10.2174\/138920207781386960"},{"key":"R102","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0043246"},{"key":"R103","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03118-13"},{"key":"R104","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-015-0507-5"},{"key":"R105","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00007-12"},{"key":"R106","doi-asserted-by":"crossref","DOI":"10.1007\/978-90-481-3132-7","volume-title":"Early, Rapid and Sensitive Veterinary Molecular Diagnostics-Real Time PCR Applications","author":"Pestana","year":"2010"},{"key":"R107","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2005.12.007"},{"key":"R108","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/978-3-319-30723-7_11","article-title":"Molecular detection methods of foodborne viruses","volume-title":"Viruses in Foods","author":"Chhabra","year":"2016"},{"key":"R109","article-title":"Acquisition of CEERAM, specialized in the detection of foodborne viruses"},{"key":"R110","doi-asserted-by":"publisher","DOI":"10.3134\/ehtj.08.008"},{"key":"R111","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2016.08.027"},{"key":"R112","article-title":"RealStar\u00ae HEV RT-PCR Kit 1.0","year":"2016"},{"key":"R113","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12121"},{"key":"R114","article-title":"International standard to harmonize assays for detection of hepatitis E virus RNA","author":"Baylis","year":"2013"},{"key":"R115","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02578-10"},{"key":"R116","article-title":"The principle of LAMP method"},{"key":"R117","doi-asserted-by":"publisher","DOI":"10.1007\/s12275-015-4656-9"},{"key":"R118","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000147"},{"key":"R119","article-title":"LAMP technology - description of the lamp process"},{"key":"R120","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00498-09"},{"key":"R121","article-title":"Transcription Mediated Amplification (TMA)","year":"2017"},{"key":"R122","year":"2018"},{"key":"R123","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13355"},{"key":"R124","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13722"},{"key":"R125","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13799"},{"key":"R126","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13757"},{"key":"R127","article-title":"ampliCube HEV 2.0"},{"key":"R128","article-title":"Instructions for Use RealStar\u00ae HEV RT-PCR Kit 1.0","year":"2016"},{"key":"R129","doi-asserted-by":"publisher","DOI":"10.1186\/1743-422X-11-72"},{"key":"R130","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btm404"},{"key":"R131","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.482"},{"key":"R132","article-title":"The global prevalence of hepatitis A virus infection and susceptibility: a systematic review","year":"2010"},{"key":"R133","doi-asserted-by":"publisher","DOI":"10.4103\/0973-6247.83238"},{"key":"R134","doi-asserted-by":"publisher","DOI":"10.2147\/HMER.S63417"},{"key":"R135","first-page":"667","article-title":"Comparison of the reliability of two ELISA kits for detecting IgM antibody against hepatitis E virus","volume":"42","author":"Zhou","year":"2008","journal-title":"Zhonghua Yu Fang Yi Xue Za Zhi"},{"key":"R136","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2015.07.302"},{"key":"R137","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02343-15"},{"key":"R138","doi-asserted-by":"publisher","DOI":"10.1086\/654801"},{"key":"R139","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.23785"},{"key":"R140","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2013.10.003"},{"key":"R141","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.4269\/ajtmh.2008.78.1012","article-title":"Occupational exposure to hepatitis E virus (HEV) in swine workers","volume":"78","author":"Galiana","year":"2008","journal-title":"Am J Trop Med Hyg"},{"key":"R142","article-title":"A comparison of three anti-HEV IgG EIA screening kits and one confirmatory immunodot assay in blood donor samples in Switzerland","volume-title":"Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)","author":"Schnegg","year":"2012"},{"key":"R143","first-page":"1087","article-title":"Comparison of two diagnostic reagents to detect anti-hepatitis E virus IgG antibodies","volume":"24","author":"Yan","year":"2008","journal-title":"Chinese Journal of Zoonoses"},{"key":"R144","doi-asserted-by":"publisher","DOI":"10.1016\/j.jceh.2015.10.001"},{"key":"R145","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.18.9860"},{"key":"R146","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510270532"},{"key":"R147","doi-asserted-by":"crossref","first-page":"2558","DOI":"10.1128\/AEM.59.8.2558-2562.1993","article-title":"Detection of hepatitis E virus in raw and treated wastewater with the polymerase chain reaction","volume":"59","author":"Jothikumar","year":"1993","journal-title":"Appl Environ Microbiol"},{"key":"R148","doi-asserted-by":"publisher","DOI":"10.3201\/eid1805.111712"},{"key":"R149","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES2013.18.31.20550"},{"key":"R150","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.05942-11"}],"container-title":["Journal of Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmm\/10.1099\/jmm.0.000706?crawler=true","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T19:56:32Z","timestamp":1603914992000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmm\/10.1099\/jmm.0.000706"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,1]]},"references-count":150,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4,1]]}},"URL":"https:\/\/doi.org\/10.1099\/jmm.0.000706","relation":{},"ISSN":["0022-2615","1473-5644"],"issn-type":[{"value":"0022-2615","type":"print"},{"value":"1473-5644","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,1]]}}}