{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:07:55Z","timestamp":1784074075405,"version":"3.55.0"},"reference-count":20,"publisher":"Microbiology Society","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,6,1]]},"abstract":"Atopic dermatitis (AD) is a chronic skin disease that affects up to 20\u200a% of the paediatric population worldwide. \n \n Staphylococcus aureus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> colonizes anterior nares and can be transmitted in the home environment, aggravating AD. This study aimed to detect \n \n S. aureus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> from nares of AD patients and their family contacts, as well as to evaluate the antimicrobial resistance, virulence and clonality of these isolates. Among the 48 family groups investigated, 30 groups were selected, as both the child and his\/her respective contact had methicillin-sensitive \n \n S. aureus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> (MSSA) (24 cases; 54 MSSA isolates) or methicillin-resistant \n \n S. aureus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> (MRSA) isolates (6 cases; 13 MRSA isolates). All MRSA isolates carried SCCmec<\/jats:italic> IV. \n \n S. aureus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> carrying PVL genes were detected in 60\u200a% of patients. Pulsed-field gel electrophoresis (PFGE) analysis was performed for 31 isolates from 15 family groups: all 6 with MRSA and 9 with MSSA isolates. Similar genotypic profiles between isolates from patients and their family contacts were noted in 10 (66.6\u200a%) family groups, 5 (83.3\u200a%) of the MRSA family groups and 5 (55.5\u200a%) of the MSSA family groups, indicating that the pathogen was transmitted through family contacts.<\/jats:p>","DOI":"10.1099\/jmm.0.001197","type":"journal-article","created":{"date-parts":[[2020,5,20]],"date-time":"2020-05-20T09:14:38Z","timestamp":1589966078000},"page":"850-853","source":"Crossref","is-referenced-by-count":4,"title":["Staphylococcus aureus nasal isolates may have the same genetic profile in atopic dermatitis paediatric patients and their close contacts"],"prefix":"10.1099","volume":"69","author":[{"given":"Fernanda Sampaio","family":"Cavalcante","sequence":"first","affiliation":[{"name":"Campus Maca\u00e9, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celina Vieira da Cunha Guedes","family":"Alvarenga","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Infec\u00e7\u00e3o Hospitalar, Departamento de Microbiologia M\u00e9dica, Instituto de Microbiologia Paulo de G\u00f3es, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Saintive","sequence":"additional","affiliation":[{"name":"Instituto de Puericultura e Pediatria Martag\u00e3o Gesteira, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliane de","family":"Dios Abad","sequence":"additional","affiliation":[{"name":"Instituto de Puericultura e Pediatria Martag\u00e3o Gesteira, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis de","family":"Carvalho Ferreira","sequence":"additional","affiliation":[{"name":"Universidade Veiga de Almeida and Universidade Est\u00e1cio de S\u00e1, Rio de Janeiro, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K\u00e1tia Regina","family":"Netto dos Santos","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Infec\u00e7\u00e3o Hospitalar, Departamento de Microbiologia M\u00e9dica, Instituto de Microbiologia Paulo de G\u00f3es, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2017.01.009"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.129"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra074081"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.3.1008-1015.2000"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.44.5.1686-1691.2006"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1590\/1414-431x20154221"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2018.12.014"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00698-07"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1080\/000155501317140124"},{"key":"R10","first-page":"390","volume-title":"Manual of Clinical Microbiology","author":"Bannerman","year":"2003"},{"key":"R11","volume-title":"Performance standards for antimicrobial disk susceptibility test \u2013 27th ed. 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