{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T03:48:50Z","timestamp":1781754530126,"version":"3.54.5"},"reference-count":33,"publisher":"Microbiology Society","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,8,1]]},"abstract":"<jats:p>\n                  <jats:bold>Introduction.<\/jats:bold> Periprosthetic joint infections caused by methicillin-resistant <jats:italic>\n                     <jats:named-content content-type=\"species\">\n                        <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/doi.org\/10.1601\/nm.11043\" xlink:type=\"simple\">Staphylococcus aureus<\/jats:ext-link>\n                     <\/jats:named-content>\n                  <\/jats:italic> (MRSA-PJIs) are rare, with only a few studies reporting the treatment outcomes and even fewer reporting outcomes with one-stage exchange.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Aim<jats:italic>.<\/jats:italic>\n                  <\/jats:bold> This study aims to analyse the outcomes of one-stage exchange in the management of MRSA-PJIs.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Methodology.<\/jats:bold> Patients with MRSA-PJI of the hip and knee, who were treated with a one-stage exchange between 2001 and 2018 were enrolled in this study. The final cohort comprised of 29 patients, which included 23 hips and six knees. The mean follow-up was 5.3 years (1\u20139 years). Reinfection and complications rates after the one-stage exchange were analysed.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Results.<\/jats:bold> Overall infection control could be achieved in 93.1\u200a% (27 out of 29 patients). The overall revision rate was 31.0% (9 patients), with three patients requiring an in-hospital revision (10.3\u200a%). Six patients had to be revised after hospital discharge (20.7\u200a%). Of the two reinfections, one had a growth of MRSA while the other was of methicillin-sensitive <jats:italic>Staphyloccocus epidermidis<\/jats:italic>.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusion.<\/jats:bold> One-stage exchange surgery using current techniques could improve surgical outcomes with excellent results in the management of MRSA-PJIs.<\/jats:p>","DOI":"10.1099\/jmm.0.001229","type":"journal-article","created":{"date-parts":[[2020,7,8]],"date-time":"2020-07-08T13:15:19Z","timestamp":1594214119000},"page":"1100-1104","source":"Crossref","is-referenced-by-count":6,"title":["Improved treatment strategies can result in better outcomes following one-stage exchange surgery for MRSA periprosthetic joint infection"],"prefix":"10.1099","volume":"69","author":[{"given":"Malte","family":"Ohlmeier","sequence":"first","affiliation":[{"name":"Department of Joint Surgery, Helios ENDO-Klinik Hamburg, Holstenstrasse 2, 22767 Hamburg, 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