{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T13:16:32Z","timestamp":1781270192809,"version":"3.54.1"},"reference-count":47,"publisher":"Microbiology Society","issue":"2","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,1]]},"abstract":"\n Introduction.<\/jats:bold>\n \n \n Chlamydia psittaci<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> is primarily a pathogen of birds but can also cause disease in other species. Equine reproductive loss caused by \n \n C. psittaci<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> has recently been identified in Australia where cases of human disease were also reported in individuals exposed to foetal membranes from an ill neonatal foal in New South Wales.<\/jats:p>\n \n Hypothesis\/Gap Statement.<\/jats:bold> The prevalence of \n \n C. psittaci<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> in association with equine reproductive over time and in different regions of Australia is not known.<\/jats:p>\n \n Aim.<\/jats:bold> This study was conducted to detect \n \n C. psittaci<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> in equine abortion cases in Australia using archived samples spanning 25\u2009years.<\/jats:p>\n \n Methodology.<\/jats:bold> We tested for \n \n C. psittaci<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> in 600 equine abortion cases reported in Australia between 1994 to 2019 using a \n \n Chlamydiaceae<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> real-time quantitative PCR assay targeting the 16S rRNA gene followed by high-resolution melt curve analysis. Genotyping and phylogenetic analysis was performed on positive samples.<\/jats:p>\n \n Results.<\/jats:bold> The overall prevalence of \n \n C. psittaci<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> in material from equine abortion cases was 6.5\u200a%. \n \n C. psittaci<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>-positive cases were detected in most years that were represented in this study and occurred in Victoria (prevalence of 7.6\u200a%), New South Wales (prevalence of 3.9\u200a%) and South Australia (prevalence of 15.4\u200a%). Genotyping and phylogenetic analysis showed that the \n \n C. psittaci<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> detected in the equine abortion cases clustered with the parrot-associated 6BC clade (genotype A\/ST24), indicating that infection of horses may be due to spillover from native Australian parrots.<\/jats:p>\n \n Conclusion.<\/jats:bold> This work suggests that \n \n C. psittaci<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> has been a signi\ufb01cant agent of equine abortion in Australia for several decades and underscores the importance of taking appropriate protective measures to avoid infection when handling equine aborted material.<\/jats:p>","DOI":"10.1099\/jmm.0.001284","type":"journal-article","created":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T14:18:52Z","timestamp":1606832332000},"source":"Crossref","is-referenced-by-count":23,"title":["A 25-year retrospective study of Chlamydia psittaci in association with equine 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