{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T01:51:46Z","timestamp":1788573106083,"version":"build-2803163510"},"reference-count":15,"publisher":"Microbiology Society","issue":"3","license":[{"start":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T00:00:00Z","timestamp":1646784000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"crossref","award":["BB\/S002103\/1"],"award-info":[{"award-number":["BB\/S002103\/1"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"crossref","award":["BB\/S005897\/1"],"award-info":[{"award-number":["BB\/S005897\/1"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"crossref","award":["BB\/S019901\/1"],"award-info":[{"award-number":["BB\/S019901\/1"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,3,9]]},"abstract":"<jats:p>\n                    The Gram-negative bacterium\n                    <jats:italic>\n                      <jats:named-content content-type=\"species\">\n                        <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/doi.org\/10.1601\/nm.3408\" xlink:type=\"simple\">Actinobacillus pleuropneumoniae<\/jats:ext-link>\n                      <\/jats:named-content>\n                    <\/jats:italic>\n                    is the causative agent of pleuropneumonia in pigs, its only known natural host. Typical symptoms of peracute disease include fever, apathy and anorexia, and time from infection to death may only be 6\u2009h. Severe lung lesions result from presence of one or two of the ApxI-III toxins. Control is through good husbandry practice, vaccines and antibiotic use. Culture and presence of the species-specific\n                    <jats:italic>apxIV<\/jats:italic>\n                    gene by PCR confirms diagnosis, and identification of serovar, of which 19 are known, informs on appropriate vaccine use and epidemiology.\n                  <\/jats:p>","DOI":"10.1099\/jmm.0.001483","type":"journal-article","created":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T11:16:04Z","timestamp":1646824564000},"source":"Crossref","is-referenced-by-count":32,"title":["JMM Profile: Actinobacillus pleuropneumoniae: a major cause of lung disease in pigs but difficult to control and eradicate"],"prefix":"10.1099","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9345-5642","authenticated-orcid":false,"given":"Oliver W.","family":"Stringer","sequence":"first","affiliation":[{"name":"Department of Infectious Disease, Section of Paediatric Infectious Disease, Imperial College London, St Mary\u2019s Campus, London, W2 1PG, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4196-1751","authenticated-orcid":false,"given":"Yanwen","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease, Section of Paediatric Infectious Disease, Imperial College London, St Mary\u2019s Campus, London, W2 1PG, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8491-4779","authenticated-orcid":false,"given":"Janine T.","family":"Boss\u00e9","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease, Section of Paediatric Infectious Disease, Imperial College London, St Mary\u2019s Campus, London, W2 1PG, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6368-4724","authenticated-orcid":false,"given":"Paul R.","family":"Langford","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease, Section of Paediatric Infectious Disease, Imperial College London, St Mary\u2019s Campus, London, W2 1PG, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.119.3.357"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-33-3-510"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1002\/9781119350927"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2021.109021"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01845-07"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00535-10"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2021.728660"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1177\/1040638720931469"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1111\/tbed.12739"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.ARBA-0022-2017"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.00311"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1051\/vetres\/2010037"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00226-20"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2018.02.028"},{"key":"R15","doi-asserted-by":"publisher","DOI":"10.1017\/S1466252321000074"}],"container-title":["Journal of Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmm\/10.1099\/jmm.0.001483?crawler=true&mimetype=application\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,14]],"date-time":"2023-12-14T15:32:06Z","timestamp":1702567926000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmm\/10.1099\/jmm.0.001483"}},"subtitle":["This article is part of the JMM Profiles collection."],"short-title":[],"issued":{"date-parts":[[2022,3,9]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3,9]]}},"URL":"https:\/\/doi.org\/10.1099\/jmm.0.001483","relation":{},"ISSN":["0022-2615","1473-5644"],"issn-type":[{"value":"0022-2615","type":"print"},{"value":"1473-5644","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,9]]}}}