{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T22:17:24Z","timestamp":1790806644745,"version":"4.1.0"},"reference-count":13,"publisher":"Microbiology Society","issue":"5","license":[{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Department for Environment, Food and Rural Affairs","award":["SV3045"],"award-info":[{"award-number":["SV3045"]}]},{"name":"Department for Environment, Food and Rural Affairs","award":["SE0559"],"award-info":[{"award-number":["SE0559"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,31]]},"abstract":"<jats:p>Louping ill virus (LIV) is a single-stranded, positive-sense RNA virus within the genus <jats:italic>Flavivirus<\/jats:italic> that is transmitted to vertebrate hosts by bites from infected ticks, the arthropod vector. The virus affects livestock in upland areas of Great Britain and Ireland, resulting in a febrile illness that can progress to fatal encephalitis. Prevention of the disease is facilitated by combining acaricide treatment, land management and vaccination strategies. However, vaccines have been discontinued in recent years. Although rare, LIV can be transmitted to and cause disease in humans. Consequently, LIV infection is a threat to human and veterinary health and can impact on the rural economy.<\/jats:p>","DOI":"10.1099\/jmm.0.001502","type":"journal-article","created":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T17:15:57Z","timestamp":1653326157000},"source":"Crossref","is-referenced-by-count":5,"title":["JMM Profile: Louping ill virus"],"prefix":"10.1099","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0106-2185","authenticated-orcid":false,"given":"Arran J.","family":"Folly","sequence":"first","affiliation":[{"name":"Vector-borne diseases, Virology Department, Animal and Plant Health Agency, Woodham Lane, Weybridge, KT15 3NB, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6022-348X","authenticated-orcid":false,"given":"Lorraine M.","family":"McElhinney","sequence":"additional","affiliation":[{"name":"Viral Zoonoses, Virology Department, Animal and Plant Health Agency, Woodham Lane, Weybridge, KT15 3NB, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6106-9373","authenticated-orcid":false,"given":"Nicholas","family":"Johnson","sequence":"additional","affiliation":[{"name":"Vector-borne diseases, Virology Department, Animal and Plant Health Agency, Woodham Lane, Weybridge, KT15 3NB, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","first-page":"325","article-title":"The nature of louping ill","volume":"11","author":"Greig","year":"1931","journal-title":"Vet Rec"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.062356-0"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1016\/0163-4453(91)92756-u"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.031641-0"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1099\/acmi.imav2019.po0034"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviromet.2006.05.025"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.3201\/eid2601.191085"},{"key":"R8","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1099\/0022-1317-79-5-981","article-title":"Tracing the origins of louping ill virus by molecular phylogenetic analysis","volume":"79","author":"McGuire","year":"1995","journal-title":"J Gen Virol"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0008133"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1007\/s10493-015-9952-x"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.3390\/v10060329"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ttbdis.2018.09.007"},{"key":"R13","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/S0034-5288(18)30572-1","article-title":"Response of sheep to experimental concurrent infection with tick-borne fever (Cytoecetes phagocytophila) and louping-ill virus","volume":"41","author":"Reid","year":"1986","journal-title":"Res Vet Sci"}],"container-title":["Journal of Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmm\/10.1099\/jmm.0.001502?crawler=true&mimetype=application\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,14]],"date-time":"2023-12-14T20:33:12Z","timestamp":1702585992000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmm\/10.1099\/jmm.0.001502"}},"subtitle":["This article is part of the JMM Profiles collection."],"short-title":[],"issued":{"date-parts":[[2022,5,31]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5,31]]}},"URL":"https:\/\/doi.org\/10.1099\/jmm.0.001502","relation":{},"ISSN":["0022-2615","1473-5644"],"issn-type":[{"value":"0022-2615","type":"print"},{"value":"1473-5644","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,31]]}}}