{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:32:59Z","timestamp":1787790779085,"version":"build-2784847793"},"reference-count":12,"publisher":"Microbiology Society","issue":"5","license":[{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,31]]},"abstract":"<jats:p>\n                  <jats:italic>\n                     <jats:named-content content-type=\"species\">\n                        <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/doi.org\/10.1601\/nm.10553\" xlink:type=\"simple\">Achromobacter xylosoxidans<\/jats:ext-link>\n                     <\/jats:named-content>\n                  <\/jats:italic> is associated with resilient nosocomial infections, with bacteraemia, pneumonia and chronic cystic fibrosis lung infection being the most common clinical presentations. Innate multi-drug resistance and a suite of virulence factors select for <jats:italic>\n                     <jats:named-content content-type=\"species\">\n                        <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/doi.org\/10.1601\/nm.10553\" xlink:type=\"simple\">A. xylosoxidans<\/jats:ext-link>\n                     <\/jats:named-content>\n                  <\/jats:italic> infection during long-term antibiotic therapy, contributing to its persistence, treatment recalcitrance, association with poor clinical outcomes and emergence as a problematic pathogen. Horizontal gene transfer and maintenance of large genomes underpin the resilience and cosmopolitan lifestyle of <jats:italic>\n                     <jats:named-content content-type=\"species\">\n                        <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/doi.org\/10.1601\/nm.10553\" xlink:type=\"simple\">A. xylosoxidans<\/jats:ext-link>\n                     <\/jats:named-content>\n                  <\/jats:italic>, and complicate its phylogenetic characterization.<\/jats:p>","DOI":"10.1099\/jmm.0.001505","type":"journal-article","created":{"date-parts":[[2022,5,19]],"date-time":"2022-05-19T16:15:59Z","timestamp":1652976959000},"source":"Crossref","is-referenced-by-count":19,"title":["JMM Profile: Achromobacter xylosoxidans: the cloak-and-dagger opportunist"],"prefix":"10.1099","volume":"71","author":[{"given":"Benjamin M.","family":"Bonis","sequence":"first","affiliation":[{"name":"Department of Microbiology & Immunology, University of Minnesota Medical School, 689 23rd Ave. SE, Minneapolis, MN 55455, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3841-1676","authenticated-orcid":false,"given":"Ryan C.","family":"Hunter","sequence":"additional","affiliation":[{"name":"Department of Microbiology & Immunology, University of Minnesota Medical School, 689 23rd Ave. SE, Minneapolis, MN 55455, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.1971.tb00607.x"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1016\/0732-8893(85)90025-2"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.1998.tb02306.x"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2006.05.011"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1093\/gbe\/evx061"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1016\/S1569-1993(12)60142-8"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00814-12"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01025-20"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201406-288FR"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01243-12"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00136-20"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02911-20"}],"container-title":["Journal of Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmm\/10.1099\/jmm.0.001505?crawler=true&mimetype=application\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,14]],"date-time":"2023-12-14T20:24:34Z","timestamp":1702585474000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmm\/10.1099\/jmm.0.001505"}},"subtitle":["This article is part of the JMM Profiles collection."],"short-title":[],"issued":{"date-parts":[[2022,5,31]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5,31]]}},"URL":"https:\/\/doi.org\/10.1099\/jmm.0.001505","relation":{},"ISSN":["0022-2615","1473-5644"],"issn-type":[{"value":"0022-2615","type":"print"},{"value":"1473-5644","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,31]]}}}