{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T21:57:21Z","timestamp":1775253441655,"version":"3.50.1"},"reference-count":15,"publisher":"Microbiology Society","issue":"11","funder":[{"DOI":"10.13039\/501100005809","name":"Hyderabad Eye Research Foundation","doi-asserted-by":"crossref","award":["123#"],"award-info":[{"award-number":["123#"]}],"id":[{"id":"10.13039\/501100005809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11,11]]},"abstract":"<jats:p>\n                  <jats:bold>Introduction<\/jats:bold>. Injudicious use of antibiotics often leads to antibiotic resistance which contributes to significant morbidity and mortality. Knowledge of local antibiogram is important in informing appropriate empiric antimicrobial therapy.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Hypothesis \/ Gap<\/jats:bold>. It is the first and largest study that examines bacterial isolates from multiple ocular infections across South India and provides a overview of susceptibility patterns for each individual bacteria in the detailed interactive dashboard.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Aim<\/jats:bold>. To study the landscape of bacterial antibiotic susceptibility patterns of ocular infections in patients undergoing microbiological investigations across a multi-tier ophthalmology network in India.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Methodology<\/jats:bold>. This cross-sectional hospital-based study included 15\u200a822\u2009patients in whom microbiology samples were analysed between September 2013 and December 2021. Ocular tissue of patients in whom a microbiology sample was processed in at least one eye were included as cases. The data were collected using an indigenously developed electronic medical record (EMR) system.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Results<\/jats:bold>. Among the 15\u200a822\u2009patients, bacteria (51.06\u200a%) was the most common aetiology, followed by fungus (38.27\u200a%). The majority of the patients were male (68.10\u200a%) and the majority were adults (90.01\u200a%). The most common age group was during the sixth decade with 2914 (18.42\u200a%) patients. The patients were more commonly from the lower socio-economic status (51.61\u200a%) and rural geography (46.82\u200a%). The majority of the specimens sent for microbiological analysis were corneal scraping (68.61\u200a%). Gram-positive cocci and Gram-positive bacilli were most sensitive towards vancomycin (86.83 and 92.89% respectively) followed by cefazolin (80.88\u200a%) and amikacin, while Gram-negative bacilli were most sensitive towards ofloxacin (65.24%).<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusion<\/jats:bold>. The most common aetiology of infection in ocular disease is bacterial and the majority of the patients presented from the rural geography and from lower socio-economic status. While vancomycin continues to be the drug of choice for Gram-positive organisms, increasing resistance to fluoroquinolones and ceftazidime was observed. Adoption of this model will enable access to antimicrobial susceptibility data, leading to reliable decisions and better clinical outcomes.<\/jats:p>","DOI":"10.1099\/jmm.0.001598","type":"journal-article","created":{"date-parts":[[2022,11,11]],"date-time":"2022-11-11T15:16:52Z","timestamp":1668179812000},"source":"Crossref","is-referenced-by-count":3,"title":["The landscape of bacterial antibiotic susceptibility in a multi-tier ophthalmology network in India: an electronic medical record driven analytics report"],"prefix":"10.1099","volume":"71","author":[{"given":"Anthony Vipin","family":"Das","sequence":"first","affiliation":[{"name":"Indian Health Outcomes, Public Health, and Economics Research Centre, Hyderabad, Telangana, India"},{"name":"Department of eyeSmart EMR & AEye, L V Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8421-1977","authenticated-orcid":false,"given":"Joveeta","family":"Joseph","sequence":"additional","affiliation":[{"name":"Jhaveri Microbiology Center, L V Prasad Eye Institute, Hyderabad, Telangana, India"},{"name":"The Ramoji Foundation Centre for Ocular Infections, Hyderabad"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2020.0155"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9394(03)00905-x"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000178066.24569.98"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1080\/01676830.2021.2002368"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-019-0380-8"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1086\/510393"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-018-0098-9"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2011.0358"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.4103\/0301-4738.100533"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_710_19"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.4103\/0301-4738.71678"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_500_18"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_2537_21"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1086\/503034"},{"key":"R15","doi-asserted-by":"publisher","DOI":"10.1002\/j.1875-9114.2012.01163.x"}],"container-title":["Journal of Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmm\/10.1099\/jmm.0.001598?crawler=true","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,11]],"date-time":"2022-11-11T15:16:54Z","timestamp":1668179814000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmm\/10.1099\/jmm.0.001598"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,11]]},"references-count":15,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11,11]]}},"URL":"https:\/\/doi.org\/10.1099\/jmm.0.001598","relation":{},"ISSN":["0022-2615","1473-5644"],"issn-type":[{"value":"0022-2615","type":"print"},{"value":"1473-5644","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,11]]}}}