{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:24:46Z","timestamp":1789431886749,"version":"build-2803163510"},"reference-count":15,"publisher":"Microbiology Society","issue":"2","license":[{"start":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T00:00:00Z","timestamp":1675987200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,10]]},"abstract":"\n Introduction.<\/jats:bold>\n \n \n Staphylococcus felis<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n is a coagulase-negative staphylococcal species that is commonly isolated from healthy cats. Like other commensal staphylococci,\n \n \n S. felis<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n can cause opportunistic infections, e.g. otitis externa, skin and urinary tract infections, in cats.\n <\/jats:p>\n \n Gap Statement.<\/jats:bold>\n Several studies have reported within-household transmission between humans and pets and human infections caused by coagulase-positive staphylococci. However, human infections with coagulase-negative staphylococci of zoonotic origin are relatively rare.\n <\/jats:p>\n \n Methodology.<\/jats:bold>\n Culture of a surgical site infection in a 58-year-old woman who underwent a laminectomy revealed dominant growth of\n \n \n S. felis<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n . The three cats owned by the patient were sampled to investigate potential within-household transmission.\n \n \n S. felis<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n isolates were sequenced to investigate the relatedness of the isolates and to look for virulence factors and host specific genes.\n <\/jats:p>\n \n Results.<\/jats:bold>\n All cats were colonized with\n \n \n S. felis<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n . Comparative genomics of the isolates showed that each cat was colonized with a distinct genotype. The patient\u2019s isolate clustered with isolates of one of the cats. Sequence analysis of the studied isolates together with 29 publicly available\n \n \n S. felis<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n genomes detected putative virulence factors that can be crucial in potential interspecies transmission.\n <\/jats:p>\n \n Conclusion.<\/jats:bold>\n The current case is the first reported human infection caused by\n \n \n S. felis<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n and highlights the zoonotic potential of this bacterial species. Evidence of cat-to-human transmission was shown by comparative genomics of isolates from the patient with isolates of her cats.\n <\/jats:p>","DOI":"10.1099\/jmm.0.001661","type":"journal-article","created":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T11:18:08Z","timestamp":1676027888000},"source":"Crossref","is-referenced-by-count":22,"title":["Evidence of cat-to-human transmission of Staphylococcus felis"],"prefix":"10.1099","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4506-983X","authenticated-orcid":false,"given":"Gregorius J.","family":"Sips","sequence":"first","affiliation":[{"name":"Present address: Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands"},{"name":"Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center, Rotterdam, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3256-3970","authenticated-orcid":false,"given":"Marloes A. M.","family":"van Dijk","sequence":"additional","affiliation":[{"name":"Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7705-7342","authenticated-orcid":false,"given":"Mireille","family":"van Westreenen","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center, Rotterdam, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8181-3393","authenticated-orcid":false,"given":"Linda","family":"van der Graaf - van Bloois","sequence":"additional","affiliation":[{"name":"Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3568-4978","authenticated-orcid":false,"given":"Birgitta","family":"Duim","sequence":"additional","affiliation":[{"name":"Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1312-6115","authenticated-orcid":false,"given":"Els M.","family":"Broens","sequence":"additional","affiliation":[{"name":"Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","first-page":"954","article-title":"Coagulase positive staphylococcal colonization of humans and their household pets","volume":"50","author":"Hanselman","year":"2009","journal-title":"Can Vet J"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00109-13"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/4360525"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2018.07.002"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-37195-0_13"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-014-0524-x"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku1196"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks261"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03617-13"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-39-4-373"},{"key":"R11","first-page":"312","article-title":"Qu\u00e9bec. 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