{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T02:10:43Z","timestamp":1768702243540,"version":"3.49.0"},"reference-count":14,"publisher":"Microbiology Society","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,29]]},"abstract":"<jats:p>\n                  <jats:bold>Introduction.<\/jats:bold> Nursing and healthcare-associated pneumonia (NHCAP) mainly occurs in older people whose physical functions have declined, and it is the most common type of pneumonia in Japan, a super-ageing society. In older people who meet NHCAP criteria, respiratory tract infections are often accompanied by aspiration pneumonia.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Gap statement.<\/jats:bold> The SARS-CoV-2 Omicron variant frequently causes aspiration pneumonia and has induced a decline in physical function.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Aim.<\/jats:bold> To clarify functional outcomes at 1\u2009year after hospital discharge in SARS-CoV-2 Omicron-related NHCAP cases.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Methodology.<\/jats:bold> We compared the functional outcomes between 259\u2009patients with primary SARS-CoV-2 pneumonia and 223\u2009patients with aspiration pneumonia.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Results.<\/jats:bold> Functional decline rates for calculating the Barthel index at the time of hospital discharge were higher in the aspiration pneumonia group than the primary SARS-CoV-2 pneumonia group [114\u2009patients (51.6%) vs 70\u2009patients (27.0%), <jats:italic>P<\/jats:italic>&lt;0.0001]. Of 114\u2009patients with aspiration pneumonia who had a decline in physical function at the time of hospital discharge, 91 (79.8%) still showed functional decline 1\u2009year later. In contrast, 9.3% of patients had functional decline at 1\u2009year after hospital discharge in the primary SARS-CoV-2 pneumonia group, which was significantly lower than in the aspiration pneumonia group.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusions.<\/jats:bold> The Omicron variant showed decreased infectivity in the lungs and was less pathogenic compared with the Delta and former variants. However, physicians should recommend SARS-CoV-2 vaccination and non-pharmaceutical interventions, depending on the presence or absence of applicable criteria for NHCAP, even when the predominant strain is the Omicron variant.<\/jats:p>","DOI":"10.1099\/jmm.0.001872","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T16:17:22Z","timestamp":1724948242000},"source":"Crossref","is-referenced-by-count":4,"title":["Aspiration pneumonia after SARS-CoV-2 Omicron infection frequently induced physical functional decline in Japan"],"prefix":"10.1099","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3730-4908","authenticated-orcid":false,"given":"Naoyuki","family":"Miyashita","sequence":"first","affiliation":[{"name":"First Department of Internal Medicine, Division of Respiratory Medicine, Infectious Disease and Allergology, Kansai Medical University, Hirakata, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Nakamori","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Kansai Medical University Medical Center, Hirakata, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Ogata","sequence":"additional","affiliation":[{"name":"First Department of Internal Medicine, Division of Respiratory Medicine, Infectious Disease and Allergology, Kansai Medical University, Hirakata, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Fukuda","sequence":"additional","affiliation":[{"name":"First Department of Internal Medicine, Division of Respiratory Medicine, Infectious Disease and Allergology, Kansai Medical University, Hirakata, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihisa","family":"Yamura","sequence":"additional","affiliation":[{"name":"First Department of Internal Medicine, Division of Respiratory Medicine, Infectious Disease and Allergology, Kansai Medical University, Hirakata, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoki","family":"Ito","sequence":"additional","affiliation":[{"name":"First Department of Internal Medicine, Division of Respiratory Medicine, Infectious Disease and Allergology, Kansai Medical University, Hirakata, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resinv.2012.11.001"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2022.03.030"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2020.01.009"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1016\/j.resinv.2013.08.006"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2016.06.005"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.18852"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1046\/j.1532-5415.2001.49015.x"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2008.01597.x"},{"key":"R9","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1515\/cclm-2021-0700","article-title":"INMI covid-19 laboratory and investigation team. 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