{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T03:55:34Z","timestamp":1790913334632,"version":"4.1.0"},"reference-count":66,"publisher":"Microbiology Society","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,2,1]]},"abstract":"<jats:p>\n                  <jats:italic>Nocardia cyriacigeorgica<\/jats:italic> is a common environmental organism. It has been isolated from clinical samples in Europe, Asia and North America, predominantly from respiratory samples but also from samples from several other sites. We present a case report of an 85-year-old female patient in the UK who was found to have a multi-focal soft-tissue infection from which <jats:italic>N. cyriacigeorgica<\/jats:italic> was isolated. She had a background history of chronic obstructive pulmonary disease and corticosteroid use for polymyalgia rheumatica. During the course of her treatment echocardiography showed the presence of a mobile heart mass attached to a valve leaflet, a major Dukes criterion for endocarditis. We suggest that in cases of disseminated <jats:italic>Nocardia<\/jats:italic> infection, endocarditis should be tested for, particularly in cases failing to respond to treatment. We also review previous reports of both <jats:italic>N. cyriacigeorgica<\/jats:italic> infection, and of endocarditis due to <jats:italic>Nocardia<\/jats:italic> species and related genera.<\/jats:p>","DOI":"10.1099\/jmm.0.011593-0","type":"journal-article","created":{"date-parts":[[2009,11,3]],"date-time":"2009-11-03T22:57:02Z","timestamp":1257289022000},"page":"224-230","source":"Crossref","is-referenced-by-count":23,"title":["Nocardia cyriacigeorgica: a case of endocarditis with disseminated soft-tissue infection"],"prefix":"10.1099","volume":"59","author":[{"given":"James S.","family":"Cargill","sequence":"first","affiliation":[{"name":"Department of Microbiology, Harrogate and District Hospital, Lancaster Park Road, Harrogate, North Yorkshire, HG2 7SX, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gavin J.","family":"Boyd","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Harrogate and District Hospital, Lancaster Park Road, Harrogate, North Yorkshire, HG2 7SX, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel C.","family":"Weightman","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Harrogate and District Hospital, Lancaster Park Road, Harrogate, North Yorkshire, HG2 7SX, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.ijid.2007.06.014","article-title":"Nocardia cyriacigeorgica : pulmonary infection in a patient with Basedow-Graves disease and a short review of reported cases","volume":"12","author":"Akcaglar","year":"2008","journal-title":"Int J Infect Dis"},{"key":"R2","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0163-4453(03)00139-7","article-title":"Cavity pneumonia secondary to Tsukamurella in an AIDS patient. 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