{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:18:32Z","timestamp":1790309912439,"version":"4.1.0"},"reference-count":44,"publisher":"Microbiology Society","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,7,1]]},"abstract":"<jats:p>This study provides what we believe to be the first report of the presence of EMRSA-15 and its variants isolated from nasal swabs from 13 healthy and diseased individuals in India. The majority of the isolates belonged to staphylococcal cassette chromosome <jats:italic>mec<\/jats:italic> (SCC<jats:italic>mec<\/jats:italic>) type IV and <jats:italic>spa<\/jats:italic> type t852, whilst four isolates were non-typable and heterotypic for the presence of the <jats:italic>mecA<\/jats:italic> gene. All non-typable isolates were positive for the <jats:italic>orfX<\/jats:italic> gene by PCR and belonged to <jats:italic>spa<\/jats:italic> types t005 and t2986. They may have variant SCC<jats:italic>mec<\/jats:italic> cassettes indicating genetic changes occurring in the Indian EMRSA-15. All isolates were positive for Panton\u2013Valentine leukocidin and toxic shock syndrome toxin, which is a cause for concern. In addition to soft-tissue infections, the EMRSA-15 isolates from patients were also responsible for meningitis and brain abscesses, which is quite rare.<\/jats:p>","DOI":"10.1099\/jmm.0.017632-0","type":"journal-article","created":{"date-parts":[[2010,3,26]],"date-time":"2010-03-26T01:07:09Z","timestamp":1269565629000},"page":"815-821","source":"Crossref","is-referenced-by-count":38,"title":["Epidemic meticillin-resistant Staphylococcus aureus (EMRSA-15) variants detected in healthy and diseased individuals in India"],"prefix":"10.1099","volume":"59","author":[{"given":"Savitha","family":"Nadig","sequence":"first","affiliation":[{"name":"Sir Dorabji Tata Centre for Research in Tropical Diseases, Innovation Centre, Indian Institute of Science Campus, Bangalore 560012, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shilpa","family":"Ramachandra Raju","sequence":"additional","affiliation":[{"name":"Sir Dorabji Tata Centre for Research in Tropical Diseases, 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