{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:02:55Z","timestamp":1791237775571,"version":"4.1.0"},"reference-count":22,"publisher":"Microbiology Society","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,7,1]]},"abstract":"To investigate the antimicrobial resistance, extended-spectrum \u03b2<\/jats:italic>-lactamases (ESBLs) and clones of Klebsiella pneumoniae<\/jats:italic> isolates causing bacteraemia or urinary tract infection (UTI) in Korea, a total of 406 K. pneumoniae<\/jats:italic> isolates from patients with bacteraemia (221 isolates) and UTI (185 isolates) were collected from 10 tertiary-care Korean hospitals from July 2006 to October 2007. In vitro<\/jats:italic> antimicrobial susceptibility testing was performed for all isolates and ESBL production was tested. Multilocus sequence typing (MLST) analyses were performed to characterize genotypes of ESBL-producing K. pneumoniae<\/jats:italic> isolates. PFGE was performed for sequence type 11 (ST11) isolates. Forty-seven UTI isolates (25.4\u200a%) produced ESBLs, while 30 bacteraemia isolates (13.6\u200a%) produced ESBLs (P<\/jats:italic>=0.002). Among 77 ESBL-producing isolates, thirty-two (41.6\u200a%) produced SHV-type ESBLs. bla<\/jats:italic>\n CTX-M<\/jats:sub> genes such as bla<\/jats:italic>\n CTX-M-14<\/jats:sub> and bla<\/jats:italic>\n CTX-M-15<\/jats:sub> were detected in 36.4\u200a%. MLST and PFGE analyses showed that ST11 was dominant in ESBL-producing K. pneumoniae<\/jats:italic> isolates causing UTI (57.4\u200a%) and in those causing bacteraemia (70.0\u200a%) and has been prevalent in Korean hospitals. ST11 isolates harbour a combination of different ESBL genes. The ST11 clone of ESBL-producing K. pneumoniae<\/jats:italic> isolates prevails in Korea, but most isolates might acquire ESBL genes independently or several different clones might be distributed in Korea.<\/jats:p>","DOI":"10.1099\/jmm.0.018119-0","type":"journal-article","created":{"date-parts":[[2010,4,2]],"date-time":"2010-04-02T01:41:23Z","timestamp":1270172483000},"page":"822-828","source":"Crossref","is-referenced-by-count":62,"title":["Predominance of an ST11 extended-spectrum \u03b2-lactamase-producing Klebsiella pneumoniae clone causing bacteraemia and urinary tract infections in Korea"],"prefix":"10.1099","volume":"59","author":[{"given":"Kwan Soo","family":"Ko","sequence":"first","affiliation":[{"name":"Asian-Pacific Research Foundation for Infectious Diseases (ARFID), Seoul 135-710, Republic of Korea"},{"name":"Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon 440-746, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Young","family":"Lee","sequence":"additional","affiliation":[{"name":"Asian-Pacific Research Foundation for Infectious Diseases (ARFID), Seoul 135-710, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Yang","family":"Baek","sequence":"additional","affiliation":[{"name":"Asian-Pacific Research Foundation for Infectious Diseases (ARFID), Seoul 135-710, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Yoeun","family":"Suh","sequence":"additional","affiliation":[{"name":"Asian-Pacific Research Foundation for Infectious Diseases (ARFID), Seoul 135-710, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mi Young","family":"Lee","sequence":"additional","affiliation":[{"name":"Asian-Pacific Research Foundation for Infectious Diseases (ARFID), Seoul 135-710, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Young","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon 440-746, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joon-Sup","family":"Yeom","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Kangbuk Samung Hospital, Sungkyunkwan University School of Medicine, Seoul 110-746, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeon-Sook","family":"Kim","sequence":"additional","affiliation":[{"name":"Chungnam National University Hospital, Daejeon 301-721, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sook-In","family":"Jung","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Chonnam National University Medical School, Gwangju 501-757, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Yop","family":"Shin","sequence":"additional","affiliation":[{"name":"Jeju National University Hospital, Jeju National University School of Medicine, Jeju 690-716, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Taek","family":"Heo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Gyeongsang National University School of Medicine and Gyeongsang Institute of Health Sciences, Jinju 660-702, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki Tae","family":"Kwon","sequence":"additional","affiliation":[{"name":"Daegu Fatima Hospital, Daegu 701-600, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun Seong","family":"Son","sequence":"additional","affiliation":[{"name":"East-West Neo Medical Center, Kyunghee University, Seoul 134-727, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin-Woo","family":"Kim","sequence":"additional","affiliation":[{"name":"Kyungpook National University Hospital, Daegu 700-721, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun-Ha","family":"Chang","sequence":"additional","affiliation":[{"name":"Kyungpook National University Hospital, Daegu 700-721, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Kyun","family":"Ki","sequence":"additional","affiliation":[{"name":"Konkuk University Hospital, Seoul 143-729, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doo Ryeon","family":"Chung","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyong 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