{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:50:25Z","timestamp":1790693425373,"version":"4.1.0"},"reference-count":25,"publisher":"Microbiology Society","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,2,1]]},"abstract":"<jats:p>Antibiotic resistance of <jats:italic>Escherichia coli<\/jats:italic> isolated from urinary tract infections (UTIs) is increasing worldwide. A total of 41 <jats:italic>E. coli<\/jats:italic> isolates were obtained from urine samples from hospitalized patients with a UTI in three hospitals in the northern districts of the West Bank, Palestine during March and June 2011. Resistance rates were: erythromycin (95\u200a%), trimethoprim\u2013sulfamethoxazole (59\u200a%), ciprofloxacin (56\u200a%), gentamicin (27\u200a%), imipenem (22\u200a%), amoxicillin (93\u200a%), amoxicillin\u2013clavulanic acid (32\u200a%), ceftazidime (66\u200a%) and cefotaxime (71\u200a%). No meropenem-resistant isolates were identified in this study. Among the isolates, phylogenetic group B2 was observed in 13 isolates, D in 12 isolates, A in 11 isolates and B1 in five isolates. Thirty-five of the isolates were positive for an extended-spectrum \u03b2-lactamase phenotype. Among these isolates, the <jats:italic>bla<\/jats:italic>\n                  <jats:sub>CTX-M<\/jats:sub> gene was detected in 25, and eight harboured the <jats:italic>bla<\/jats:italic>\n                  <jats:sub>TEM<\/jats:sub> gene. None of the isolates contained the <jats:italic>bla<\/jats:italic>\n                  <jats:sub>SHV<\/jats:sub> gene. Transformation experiments indicated that some of the \u03b2-lactamase genes (i.e. <jats:italic>bla<\/jats:italic>\n                  <jats:sub>CTX-M<\/jats:sub> and <jats:italic>bla<\/jats:italic>\n                  <jats:sub>TEM<\/jats:sub>) with co-resistance to erythromycin and gentamicin were plasmid encoded and transmissible. Apart from this, enterobacterial repetitive intergenic consensus-PCR (ERIC-PCR) revealed that the 41 isolates were genetically diverse and comprised a heterogeneous population with 11 ERIC-PCR profiles at a 60\u200a% similarity level.<\/jats:p>","DOI":"10.1099\/jmm.0.067140-0","type":"journal-article","created":{"date-parts":[[2013,11,16]],"date-time":"2013-11-16T05:10:14Z","timestamp":1384578614000},"page":"229-234","source":"Crossref","is-referenced-by-count":27,"title":["Molecular characterization of Escherichia coli isolates from patients with urinary tract infections in Palestine"],"prefix":"10.1099","volume":"63","author":[{"given":"Kamel","family":"Adwan","sequence":"first","affiliation":[{"name":"Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naser","family":"Jarrar","sequence":"additional","affiliation":[{"name":"Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Awni","family":"Abu-Hijleh","sequence":"additional","affiliation":[{"name":"Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghaleb","family":"Adwan","sequence":"additional","affiliation":[{"name":"Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Awwad","sequence":"additional","affiliation":[{"name":"Central Veterinary Laboratory, Directorate of Veterinary Services and Animal Health, Ministry of Agriculture, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"r1","first-page":"591","article-title":"Molecular detection and epidemiology of extended-spectrum beta-lactamase genes prevalent in clinical isolates of Klebsiella pneumoniae and E. coli from Trinidad and Tobago","volume":"59","author":"Akpaka","year":"2010","journal-title":"West Indian Med J"},{"key":"r2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2012.09.016"},{"key":"r3","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-5-38"},{"key":"r4","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2009.074617"},{"key":"r5","article-title":"Performance Standards for Antimicrobial Susceptibility Testing; 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