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The caspofungin MICs of 37<jats:italic>A. flavus<\/jats:italic>clinical isolates collected from 14 patients with invasive aspergillosis were determined using Etest assays. Caspofungin MICs ranged from 0.012 to 0.064 mg l<jats:sup>\u22121<\/jats:sup>; the modal MIC was 0.023 mg l<jats:sup>\u22121<\/jats:sup>and the MIC<jats:sub>50<\/jats:sub>and MIC<jats:sub>90<\/jats:sub>were 0.032 and 0.064 mg l<jats:sup>\u22121<\/jats:sup>, respectively. A clear end point was noted in 24 (65\u200a%) isolates, whereas seven (19\u200a%) displayed a trailing effect and six (16\u200a%) showed paradoxical growth when exposed to caspofungin. 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