{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T11:20:59Z","timestamp":1775647259629,"version":"3.50.1"},"reference-count":12,"publisher":"Microbiology Society","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,12,1]]},"abstract":"<jats:p>A screw-capped glass tube containing a <jats:italic>Leptospira<\/jats:italic> culture accidentally broke and the laboratory worker who was handling the tube sustained a cut on his hand. The wound was flooded with the culture. The culture was that of strain MG 347 belonging to serovar Australis recovered from a patient, and it had undergone 52 passages in Ellinghausen McCullough Johnson Harris medium. The laboratory worker developed a headache 21 days after the accident and became febrile the next day. He was hospitalized for 5 days and was treated initially with doxycycline and later with ciprofloxacin. A blood sample collected on the second day of illness, after starting doxycycline therapy, yielded leptospires and the isolate, HZ 651, was identified as serovar Australis. Monoclonal antibody patterns and randomly amplified polymorphic DNA fingerprinting patterns of the isolate and strain MG 347 were identical, thus indicating that HZ 651 and MG 347 were clonal.<\/jats:p>","DOI":"10.1099\/jmm.0.45735-0","type":"journal-article","created":{"date-parts":[[2004,11,19]],"date-time":"2004-11-19T19:48:14Z","timestamp":1100893694000},"page":"1259-1262","source":"Crossref","is-referenced-by-count":11,"title":["Percutaneous exposure resulting in laboratory-acquired leptospirosis \u2013 a case report"],"prefix":"10.1099","volume":"53","author":[{"given":"A P","family":"Sugunan","sequence":"first","affiliation":[{"name":"WHO Collaborative Centre for Diagnosis, Research, Reference and Training in Leptospirosis, Regional Medical Research Centre, Indian Council of Medical Research, Post Bag No. 13, Port Blair 744 101, Andaman & Nicobar Islands, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Natarajaseenivasan","sequence":"additional","affiliation":[{"name":"WHO Collaborative Centre for Diagnosis, Research, Reference and Training in Leptospirosis, Regional Medical Research Centre, Indian Council of Medical Research, Post Bag No. 13, Port Blair 744 101, Andaman & Nicobar Islands, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Vijayachari","sequence":"additional","affiliation":[{"name":"WHO Collaborative Centre for Diagnosis, Research, Reference and Training in Leptospirosis, Regional Medical Research Centre, Indian Council of Medical Research, Post Bag No. 13, Port Blair 744 101, Andaman & Nicobar Islands, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S C","family":"Sehgal","sequence":"additional","affiliation":[{"name":"WHO Collaborative Centre for Diagnosis, Research, Reference and Training in Leptospirosis, Regional Medical Research Centre, Indian Council of Medical Research, Post Bag No. 13, Port Blair 744 101, Andaman & Nicobar Islands, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"H1-14","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1099\/00222615-46-2-173","article-title":"Differentiation of Leptospira species and serovars by PCR-restriction endonuclease analysis, arbitrarily primed PCR and low-stringency PCR","volume":"46","author":"Brown","year":"1997","journal-title":"J Med Microbiol"},{"key":"H2-14","doi-asserted-by":"crossref","first-page":"676","DOI":"10.2460\/javma.2000.216.676","article-title":"9 other authors","volume":"216","author":"Campagnolo","year":"2000","journal-title":"J Am Vet Med Assoc"},{"key":"H3-14","volume-title":"Leptospira and Leptospirosis","author":"Faine","year":"1999"},{"key":"H4-14","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1136\/pgmj.64.749.236","article-title":"Failure of penicillin prophylaxis in laboratory acquired leptospirosis","volume":"64","author":"Gilks","year":"1988","journal-title":"Postgrad Med J"},{"key":"H5-14","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1128\/JCM.35.1.92-97.1997","article-title":"LEPTO dipstick, a dipstick assay for detection of Leptospira -specific immunoglobulin M antibodies in human sera","volume":"35","author":"Gussenhoven","year":"1997","journal-title":"J Clin Microbiol"},{"key":"H6-14","first-page":"170","article-title":"Leptospirosis among rice mill workers of Salem, South India","volume":"55","author":"Natarajaseenivasan","year":"2002","journal-title":"Jpn J Infect Dis"},{"key":"H7-14","first-page":"199","article-title":"Zoonoses. 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