{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T08:57:05Z","timestamp":1777366625377,"version":"3.51.4"},"reference-count":31,"publisher":"Microbiology Society","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,9,1]]},"abstract":"<jats:p>Two <jats:italic>Salmonella enterica<\/jats:italic> serovar Typhimurium isolates and one <jats:italic>S. enterica<\/jats:italic> serovar Enteritidis isolate that were resistant to 4\u2005\u03bcg cefotaxime ml<jats:sup>\u22121<\/jats:sup> and produced CTX-M-type extended-spectrum <jats:italic>\u03b2<\/jats:italic>-lactamases (ESBLs) were characterized from patients in Hong Kong during 2003\u20132004. The <jats:italic>S<\/jats:italic>. Typhimurium strain isolated in 2003 produced a CTX-M-9 ESBL and harboured a <jats:italic>bla<\/jats:italic>\n                  <jats:sub>CTX-M-9<\/jats:sub> gene that was associated with a class I integron-containing gene cassette and <jats:italic>orf513<\/jats:italic> similar to those of In60. The second <jats:italic>S<\/jats:italic>. Typhimurium strain and the <jats:italic>S<\/jats:italic>. Enteritidis strain, both isolated in 2004, produced CTX-M-14; the former also produced TEM-1. The <jats:italic>bla<\/jats:italic>\n                  <jats:sub>CTX-M-14<\/jats:sub> gene in these two isolates was associated with the insertion sequence IS<jats:italic>Ecp1<\/jats:italic>. The CTX-M genes were present on a transferable plasmid of 62, 70 or 92\u2005kb. PFGE of <jats:italic>Xba<\/jats:italic>I-restricted total DNA from the two <jats:italic>S<\/jats:italic>. Typhimurium isolates indicated that they were not clonally related. These three isolates were also resistant to one of the other non-<jats:italic>\u03b2<\/jats:italic>-lactam antimicrobial agents tested. This is the first report of a CTX-M-9 ESBL in <jats:italic>Salmonella<\/jats:italic> in Hong Kong and the presence of <jats:italic>bla<\/jats:italic>\n                  <jats:sub>CTX-M-9<\/jats:sub> and <jats:italic>bla<\/jats:italic>\n                  <jats:sub>CTX-M-14<\/jats:sub> in <jats:italic>S<\/jats:italic>. Typhimurium.<\/jats:p>","DOI":"10.1099\/jmm.0.46637-0","type":"journal-article","created":{"date-parts":[[2006,8,16]],"date-time":"2006-08-16T18:42:50Z","timestamp":1155753770000},"page":"1245-1250","source":"Crossref","is-referenced-by-count":19,"title":["CTX-M-producing Salmonella spp. in Hong Kong: an emerging problem"],"prefix":"10.1099","volume":"55","author":[{"given":"Yujuan","family":"Jin","sequence":"first","affiliation":[{"name":"Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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