{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T09:06:04Z","timestamp":1778663164891,"version":"3.51.4"},"reference-count":9,"publisher":"Microbiology Society","issue":"8","license":[{"start":{"date-parts":[[2017,8,8]],"date-time":"2017-08-08T00:00:00Z","timestamp":1502150400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,8,8]]},"abstract":"<jats:p>\n                  <jats:bold>Introduction.<\/jats:bold> It is estimated up to 6\u200a% of prosthetic vascular grafts become infected. <jats:italic>Staphylococcus aureus<\/jats:italic> is predominant in early infection and coagulase-negative staphylococci are predominant in late infections. <jats:italic>Enterobacteriaceae<\/jats:italic> cause 14\u201340\u200a% of prosthetic vascular graft infections. This is, to our knowledge the first reported case of <jats:italic>Salmonella<\/jats:italic> gastroenteritis causing chronic prosthetic vascular graft infection (PVGI).<\/jats:p>\n               <jats:p>\n                  <jats:bold>Case presentation.<\/jats:bold> A 57\u2009years old lady presented with signs and symptoms of prosthetic vascular graft infection. Three years earlier, she had undergone a prosthetic axillo-femoral bypass graft for critical limb ischaemia. The infected prosthetic vascular graft was removed and <jats:italic>Salmonella<\/jats:italic> Typhimurium was isolated on culture. In the intervening period, <jats:italic>Salmonella<\/jats:italic> Typhimurium was isolated from a faecal specimen, collected during an episode of acute gastroenteritis. Whole-genome sequencing (WGS) showed that the respective <jats:italic>Salmonella<\/jats:italic> Typhimurium isolates differed by only a single nucleotide polymorphism (SNP). <jats:italic>Salmonella<\/jats:italic> Typhimurium was not isolated on culture of a faecal specimen collected five days following cessation of antimicrobial therapy. Six months after removal of the prosthetic graft, the patient remains under follow-up for her peripheral vascular disease, which currently requires no further surgical intervention.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusion.<\/jats:bold> This case has clear implications for the management of chronic PVGI. It is vital to collect high-quality surgical specimens for microbiological analysis and empirical choices of antibiotics are unlikely to cover all potential pathogens. It may also be prudent to enquire about a history of acute gastroenteritis when assessing patients presenting with chronic PVGI.<\/jats:p>","DOI":"10.1099\/jmmcr.0.005104","type":"journal-article","created":{"date-parts":[[2017,8,8]],"date-time":"2017-08-08T16:12:34Z","timestamp":1502208754000},"source":"Crossref","is-referenced-by-count":5,"title":["Salmonella Typhimurium gastroenteritis leading to chronic prosthetic vascular graft infection"],"prefix":"10.1099","volume":"4","author":[{"given":"Milo","family":"Cullinan","sequence":"first","affiliation":[{"name":"Freeman Hospital, Freeman Road, Newcastle Upon Tyne NE7 7DN, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Clarke","sequence":"additional","affiliation":[{"name":"Freeman Hospital, Freeman Road, Newcastle Upon Tyne NE7 7DN, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Dallman","sequence":"additional","affiliation":[{"name":"Public Health England, 61 Colindale Ave, London NW9 5EQ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Peart","sequence":"additional","affiliation":[{"name":"Freeman Hospital, Freeman Road, Newcastle Upon Tyne NE7 7DN, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah","family":"Wilson","sequence":"additional","affiliation":[{"name":"Public Health England, Citygate Gallowgate, Newcastle Upon Tyne NE1 4WH, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Weiand","sequence":"additional","affiliation":[{"name":"Freeman Hospital, Freeman Road, Newcastle Upon Tyne NE7 7DN, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2015.04.014"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1016\/j.medmal.2008.09.010"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-14-800"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1016\/0163-4453(91)91635-B"},{"key":"R5","first-page":"679","article-title":"Primary Salmonella aortic graft infection. First reported case","volume":"49","author":"Wooldridge","year":"1983","journal-title":"Am Surg"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)90321-F"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1007\/s002469900073"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800661122"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1053\/ejvx.2002.0140"}],"container-title":["JMM Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmmcr\/10.1099\/jmmcr.0.005104?crawler=true&mimetype=application\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T11:29:12Z","timestamp":1702639752000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmmcr\/10.1099\/jmmcr.0.005104"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,8]]},"references-count":9,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,8,8]]}},"URL":"https:\/\/doi.org\/10.1099\/jmmcr.0.005104","relation":{},"ISSN":["2053-3721"],"issn-type":[{"value":"2053-3721","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,8]]}}}