{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T05:20:01Z","timestamp":1780982401035,"version":"3.54.1"},"reference-count":19,"publisher":"Microbiology Society","issue":"10","license":[{"start":{"date-parts":[[2017,10,16]],"date-time":"2017-10-16T00:00:00Z","timestamp":1508112000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,10,16]]},"abstract":"<jats:p>\n                  <jats:bold>Introduction.<\/jats:bold> Species of the genus <jats:italic>Chryseobacterium<\/jats:italic> are emerging healthcare-associated pathogens, often colonizing the hospital environment. There are no clear guidelines available for antimicrobial susceptibility of this organism. In this report we present the first case, to our knowledge, of simultaneous central-line-associated bloodstream infection (CLABSI) and ventilator-associated pneumonia (VAP) due to <jats:italic>Chryseobacterium gleum<\/jats:italic> from India.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Case presentation.<\/jats:bold> A 62\u2009years old man with a history of a road traffic accident 1\u2009month previously was referred to our center for further management. He developed features of sepsis and aspiration pneumonia on day 3 of admission. Four blood cultures (two each from central and peripheral lines) and two tracheal aspirate cultures grew pure yellow colonies of bacteria. Both matrix assisted laser desorption ionization time of flight mass spectrometry, (MALDI-TOF MS; bioM\u00e9rieux, Marcy-L'Etoile, France,) and BD Phoenix (BD Biosciences, Maryland, USA) identified the organism as <jats:italic>C. gleum<\/jats:italic>. However, BD Phoenix failed to provide MIC breakpoints. The isolates of <jats:italic>C. gleum<\/jats:italic> both from blood and tracheal aspirate showed identical susceptibility patterns: resistant to cephalosporins and carbapenems and susceptible to ciprofloxacin, levofloxacin, amikacin, trimethoprim+sulfamethoxazole, piperacillin\u2013tazobactam, cefoperazone\u2013sulbactam, doxycycline, minocycline and vancomycin. Following levofloxacin therapy, the fever responded within 48\u2009h and procalcitonin levels decreased without removal of the central line or endotracheal tube. However, the patient developed sudden cardiac arrest on day 10 of treatment and could not be resuscitated.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusion.<\/jats:bold> Rapid and accurate identification of <jats:italic>C. gleum<\/jats:italic> in the laboratory, preferably based on MALDI-TOF, is essential for guiding therapy. <jats:italic>C. gleum<\/jats:italic> responds well to fluoroquinolones without the need to remove indwelling catheters.<\/jats:p>","DOI":"10.1099\/jmmcr.0.005122","type":"journal-article","created":{"date-parts":[[2017,10,16]],"date-time":"2017-10-16T10:12:40Z","timestamp":1508148760000},"source":"Crossref","is-referenced-by-count":14,"title":["Simultaneous isolation of Chryseobacterium gleum from bloodstream and respiratory tract: first case report from India"],"prefix":"10.1099","volume":"4","author":[{"given":"Vidhi","family":"Jain","sequence":"first","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nayani Amrin Fatema Afzal","family":"Hussain","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tasneem","family":"Siddiqui","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chinmoy","family":"Sahu","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malay","family":"Ghar","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Post Graduate Institute of 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