{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T18:27:59Z","timestamp":1787941679487,"version":"build-2784847793"},"reference-count":14,"publisher":"Microbiology Society","issue":"11","license":[{"start":{"date-parts":[[2017,11,2]],"date-time":"2017-11-02T00:00:00Z","timestamp":1509580800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,11,2]]},"abstract":"<jats:p>\n                  <jats:bold>Introduction.<\/jats:bold> Invasive infections by <jats:italic>Helicobacter canis<\/jats:italic> are uncommon and occur primarily in immunocompromised patients. Here, we describe a case of <jats:italic>H. canis<\/jats:italic> bacteraemia and cellulitis in a patient with end-stage renal disease (ESRD).<\/jats:p>\n               <jats:p>\n                  <jats:bold>Case presentation.<\/jats:bold> A 49-year-old male with ESRD on haemodialysis presented to an emergency department with cellulitis overlying his left upper extremity arteriovenous fistula for 3 days without constitutional symptoms. Mild leucocytosis and thrombocytopenia was noted on initial laboratory work up. The patient received a dose of vancomycin initially, and then transitioned to oral doxycycline prior to discharge 3 days later. Blood cultures drawn on admission were positive with curved Gram-negative rods at day 5. Routine sub-cultures initially failed to isolate the organism; however, small, tan colonies were observed on sheep blood agar incubated under microaerobic conditions. <jats:italic>H. canis<\/jats:italic> was identified by 16S rRNA sequencing. Antimicrobial-susceptibility testing was not performed due to poor growth and lack of interpretive guidelines. The patient was ultimately treated successfully with amoxicillin\/clavulanic acid.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusion.<\/jats:bold> This case illustrates the importance of recognizing <jats:italic>H. canis<\/jats:italic> infections in immunocompromised patients, especially in those with recent pet exposure. In addition, this case highlights the need for improved laboratory diagnostics for <jats:italic>H. canis<\/jats:italic> as isolation and identification of this fastidious organism is challenging.<\/jats:p>","DOI":"10.1099\/jmmcr.0.005126","type":"journal-article","created":{"date-parts":[[2017,11,8]],"date-time":"2017-11-08T16:12:37Z","timestamp":1510157557000},"source":"Crossref","is-referenced-by-count":8,"title":["Helicobacter canis bacteraemia and cellulitis in a patient with end-stage renal disease"],"prefix":"10.1099","volume":"4","author":[{"given":"Salika M.","family":"Shakir","sequence":"first","affiliation":[{"name":"Department of Pathology, University of Utah School of Medicine\/ARUP Laboratories, Salt Lake City, UT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret V.","family":"Powers-Fletcher","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Cincinnati Medical Center, Cincinnati, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Susan","family":"Slechta","sequence":"additional","affiliation":[{"name":"ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A.","family":"Fisher","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Utah School of Medicine\/ARUP Laboratories, Salt Lake City, UT, USA"},{"name":"ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2012.05.001"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-139-10-2495"},{"key":"R3","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1128\/jcm.31.7.1916-1917.1993","article-title":"Novel Campylobacter-like organism resembling Helicobacter fennelliae isolated from a boy with gastroenteritis and from dogs","volume":"31","author":"Burnens","year":"1993","journal-title":"J Clin Microbiol"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1086\/323405"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-009-9067-6"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12174"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01453-06"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.2007.00271.x"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01031-11"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/22.11.1954"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkn180"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1016\/j.syapm.2015.09.008"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-015-0692-z"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02548-12"}],"container-title":["JMM Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmmcr\/10.1099\/jmmcr.0.005126?crawler=true&mimetype=application\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T11:30:48Z","timestamp":1702639848000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmmcr\/10.1099\/jmmcr.0.005126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,2]]},"references-count":14,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11,2]]}},"URL":"https:\/\/doi.org\/10.1099\/jmmcr.0.005126","relation":{},"ISSN":["2053-3721"],"issn-type":[{"value":"2053-3721","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,2]]}}}