{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:29:26Z","timestamp":1761514166401},"reference-count":29,"publisher":"Microbiology Society","issue":"4","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,4,1]]},"abstract":"<jats:p>\n                  <jats:bold>Introduction.<\/jats:bold> Chagas disease is caused by infection with the protozoan <jats:italic>Trypanosoma cruzi.<\/jats:italic> It is endemic to the American continent due to the distribution of its insect vectors. The disease is occasionally imported to other continents by travel of infected individuals. It is rarely diagnosed in the Netherlands and exact numbers of infected individuals are unknown. Clinical manifestations can start with an acute phase of 4\u20138 weeks with non-specific, mild symptoms and febrile illness. In the chronic phase, it can lead to fatal cardiac and gastro-intestinal complications.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Case presentation.<\/jats:bold> We describe a case of a 40-year-old man with end-stage cardiomyopathy due to Chagas disease. He lived in Surinam for more than 20\u2009years and had an unremarkable medical history until he was hospitalized due to pneumonia and congestive heart failure. Despite antibiotic treatment and optimizing cardiac medication, his disease progressed to end-stage heart failure for which cardiac transplantation was the only remaining treatment. A left ventricular assist device (LVAD) was implanted as a bridge to transplantation. Tissue analysis after LVAD surgery revealed ongoing myocarditis caused by Chagas disease. Based on a literature review, a scheme for follow up and treatment after transplantation was postulated.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusion.<\/jats:bold> Chagas disease should be taken into account in patients from endemic countries who have corresponding clinical signs. Heart transplantation in patients with Chagas cardiomyopathy is accompanied by specific challenges due to the required immunosuppressive therapy and the thereby increased risk of reactivation of a latent <jats:italic>T. cruzi<\/jats:italic> infection.<\/jats:p>","DOI":"10.1099\/jmmcr.0.005142","type":"journal-article","created":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T14:13:40Z","timestamp":1520345620000},"source":"Crossref","is-referenced-by-count":4,"title":["An unusual case of congestive heart failure in the Netherlands"],"prefix":"10.1099","volume":"5","author":[{"given":"Marjolein C.","family":"Persoon","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier C.","family":"Manintveld","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Femke P. N.","family":"Mollema","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands"},{"name":"Present address: Department of Internal Medicine, Haaglanden Medisch Centrum, The Hague, The Netherlands."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaap J.","family":"van Hellemond","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0002410"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis910"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2012.03.015"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31612-4"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1001\/jama.298.18.2171"},{"key":"R6","first-page":"A3170","article-title":"Chagas disease in the Netherlands: an estimate of the number of patients","volume":"155","author":"Bart","year":"2011","journal-title":"Ned Tijdschr Geneeskd"},{"key":"R7","first-page":"377","article-title":"Ventricular arrhythmia in chagas disease. diagnostic, prognostic, and therapeutic features","volume":"65","author":"Rassi J\u00fanior","year":"1995","journal-title":"Arq Bras Cardiol"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12443"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.7.2.157"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2011.03444.x"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1590\/0037-8682-0505-2016"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0151038"},{"key":"R13","article-title":"Parasites \u2013 American Trypanosomiasis (also know as Chagas Disease): Centers for Disease Control and Prevention; 2014 [updated 05-02-2014"},{"key":"R14","article-title":"Parasites \u2013 American Trypanosomiasis (also known as Chagas Disease) Centers for Disease Control and Prevention; 2014 [updated 02-06-2014"},{"key":"R15","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1507574"},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004508"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.01820.x"},{"key":"R18","doi-asserted-by":"publisher","DOI":"10.1016\/j.trre.2010.12.002"},{"key":"R19","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2017.02.018"},{"key":"R20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1997.tb00278.x"},{"key":"R21","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2007.07.043"},{"key":"R22","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2010.12.046"},{"key":"R23","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMct1014204"},{"key":"R24","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.624296"},{"key":"R25","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2017.02.006"},{"key":"R26","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2008.02.017"},{"key":"R27","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12507"},{"key":"R28","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2005.00975.x"},{"key":"R29","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2009.01202.x"}],"container-title":["JMM Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmmcr\/10.1099\/jmmcr.0.005142?crawler=true&mimetype=application\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T12:30:29Z","timestamp":1702643429000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmmcr\/10.1099\/jmmcr.0.005142"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,1]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4,1]]}},"URL":"https:\/\/doi.org\/10.1099\/jmmcr.0.005142","relation":{},"ISSN":["2053-3721"],"issn-type":[{"value":"2053-3721","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,1]]}}}