{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T01:09:53Z","timestamp":1770512993318,"version":"3.49.0"},"reference-count":13,"publisher":"Microbiology Society","issue":"4","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,4,1]]},"abstract":"<jats:p>\n                  <jats:bold>Introduction.<\/jats:bold>\n                  <jats:italic>Aureobasidium pullulans<\/jats:italic> is a dematiaceous, yeast-like fungus that is ubiquitous in nature and can colonize human hair and skin. It has been implicated clinically as causing skin and soft tissue infections, meningitis, splenic abscesses and peritonitis. We present, to our knowledge, the second case of isolation of this organism in a patient with AIDS along with a review of the literature on human infection with <jats:italic>A. pullulans<\/jats:italic>.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Case presentation.<\/jats:bold> A 49-year-old man with advanced AIDS and a history of recurrent oesophageal candidiasis was admitted with nausea with vomiting, and odynophagia. He was treated as having a recurrence of oesophageal candidiasis. Given prior <jats:italic>Candida albicans<\/jats:italic> isolate susceptibilities and chronic suppression with fluconazole, he was started on micafungin with eventual improvement in his symptoms. A positive blood culture from admission was initially reported to be growing yeast, but four days later the isolate was recognized as a dematiaceous fungus. The final identification of <jats:italic>A. pullulans<\/jats:italic> was not available until 1\u2009month after admission. He had completed a 3-week course of micafungin prior to the identification of the isolate, and repeat cultures were negative.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusion.<\/jats:bold>\n                  <jats:italic>A. pullulans<\/jats:italic> fungemia is rare but can occur in patients with immune suppression or indwelling catheters. The significance of isolating <jats:italic>A. pullulans<\/jats:italic> from a blood culture in terms of whether it is the causative agent of a state of disease often cannot be determined because skin colonization is possible. Further work is needed to clarify the clinical implications of <jats:italic>A. pullulans<\/jats:italic> fungemia.<\/jats:p>","DOI":"10.1099\/jmmcr.0.005144","type":"journal-article","created":{"date-parts":[[2018,3,14]],"date-time":"2018-03-14T14:12:34Z","timestamp":1521036754000},"source":"Crossref","is-referenced-by-count":16,"title":["Fungemia caused by Aureobasidium pullulans in a patient with advanced AIDS: a case report and review of the medical literature"],"prefix":"10.1099","volume":"5","author":[{"given":"Jaimie","family":"Mittal","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Division of Infectious Diseases, Albert Einstein College of Medicine and Montefiore Medical Center, 3411 Wayne Ave., Bronx, NY 10467, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendy A.","family":"Szymczak","sequence":"additional","affiliation":[{"name":"Department of Pathology, Albert Einstein College of Medicine and Montefiore Medical Center, 111 E. 210th Street, Bronx, NY 10467, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liise-anne","family":"Pirofski","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Infectious Diseases, Albert Einstein College of Medicine and Montefiore Medical Center, 3411 Wayne Ave., Bronx, NY 10467, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin T.","family":"Galen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Hospital Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, 1825 Eastchester Rd., Bronx, NY 10461, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2008.02.004"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.9.4483-4485.2003"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1590\/0037-8682-0117-2013"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1080\/00313020802436782"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1016\/j.idcr.2017.08.017"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2009.111"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1080\/23120053.2016.1155799"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00019-10"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.03095-14"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1093\/clind\/16.2.338-a"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2004.10.007"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.3109\/13693786.2010.490925"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-4453(86)91388-5"}],"container-title":["JMM Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmmcr\/10.1099\/jmmcr.0.005144?crawler=true&mimetype=application\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T12:29:11Z","timestamp":1702643351000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jmmcr\/10.1099\/jmmcr.0.005144"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,1]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4,1]]}},"URL":"https:\/\/doi.org\/10.1099\/jmmcr.0.005144","relation":{},"ISSN":["2053-3721"],"issn-type":[{"value":"2053-3721","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,1]]}}}