{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T04:34:19Z","timestamp":1779165259875,"version":"3.51.4"},"reference-count":53,"publisher":"Microbiology Society","issue":"2","license":[{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,2,1]]},"abstract":"\n \u2018\n Candidatus<\/jats:italic>\n Ornithobacterium hominis\u2019 represents a new member of the\n \n \n Flavobacteriaceae<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n detected in 16S rRNA gene surveys of people from South-East Asia, Africa and Australia. It frequently colonizes the infant nasopharynx at high proportional abundance, and we demonstrate its presence in 42\u200a% of nasopharyngeal swabs from 12-month-old children in the Maela refugee camp in Thailand. The species, a Gram-negative bacillus, has not yet been cultured, but the cells can be identified in mixed samples by fluorescent hybridization. Here, we report seven genomes assembled from metagenomic data, two to improved draft standard. The genomes are approximately 1.9\u2009Mb, sharing 62\u200a% average amino acid identity with the only other member of the genus, the bird pathogen\n \n \n Ornithobacterium rhinotracheale<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n . The draft genomes encode multiple antibiotic-resistance genes, competition factors,\n \n \n Flavobacterium johnsoniae<\/jats:ext-link>\n <\/jats:named-content>\n -\n <\/jats:italic>\n like gliding motility genes and a homologue of the\n \n \n Pasteurella multocida<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n mitogenic toxin. Intra- and inter-host genome comparison suggests that colonization with this bacterium is both persistent and strain exclusive.\n <\/jats:p>","DOI":"10.1099\/mgen.0.000247","type":"journal-article","created":{"date-parts":[[2019,2,5]],"date-time":"2019-02-05T09:12:52Z","timestamp":1549357972000},"source":"Crossref","is-referenced-by-count":19,"title":["'Candidatus Ornithobacterium hominis': insights gained from draft genomes obtained from nasopharyngeal swabs"],"prefix":"10.1099","volume":"5","author":[{"given":"Susannah J.","family":"Salter","sequence":"first","affiliation":[{"name":"1\u200bPathogen Genomics, Wellcome Sanger Institute, Hinxton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Scott","sequence":"additional","affiliation":[{"name":"1\u200bPathogen Genomics, Wellcome Sanger Institute, Hinxton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew J.","family":"Page","sequence":"additional","affiliation":[{"name":"1\u200bPathogen Genomics, Wellcome Sanger Institute, Hinxton, UK"},{"name":"\u2020\u200bPresent address: Quadram Institute Bioscience, Norwich, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan","family":"Tracey","sequence":"additional","affiliation":[{"name":"1\u200bPathogen Genomics, Wellcome Sanger Institute, Hinxton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus C.","family":"de Goffau","sequence":"additional","affiliation":[{"name":"1\u200bPathogen Genomics, Wellcome Sanger Institute, Hinxton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Cormie","sequence":"additional","affiliation":[{"name":"1\u200bPathogen Genomics, Wellcome Sanger Institute, Hinxton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernardo","family":"Ochoa-Monta\u00f1o","sequence":"additional","affiliation":[{"name":"2\u200bDepartment of Biochemistry, University of Cambridge, Cambridge, UK"},{"name":"\u2021\u200bPresent address: Illumina Cambridge Ltd, Little Chesterford, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clare L.","family":"Ling","sequence":"additional","affiliation":[{"name":"3\u200bShoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand"},{"name":"4\u200bCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiraporn","family":"Tangmanakit","sequence":"additional","affiliation":[{"name":"3\u200bShoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Turner","sequence":"additional","affiliation":[{"name":"4\u200bCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK"},{"name":"5\u200bCambodia-Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian","family":"Parkhill","sequence":"additional","affiliation":[{"name":"1\u200bPathogen Genomics, Wellcome Sanger Institute, Hinxton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0005975"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6890-11-2"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-08717-0"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0128064"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-016-0182-1"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2014.195"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0038271"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0054026"},{"key":"R9","volume-title":"Cough or Difficulty Breathing. 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