{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T22:13:02Z","timestamp":1740175982357,"version":"3.37.3"},"reference-count":17,"publisher":"Microbiology Society","issue":"6","license":[{"start":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T00:00:00Z","timestamp":1616544000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"crossref","award":["206194"],"award-info":[{"award-number":["206194"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"crossref","award":["206194"],"award-info":[{"award-number":["206194"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003285","name":"Ministerio de Salud de la Naci\u00f3n","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003285","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,3,24]]},"abstract":"Specific lineages of serogroup O1 \n \n Vibrio cholerae<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> are notorious for causing cholera pandemics, of which there have been seven since the 1800s. Much is known about the sixth pandemic (1899\u20131923) and the ongoing seventh pandemic (1961\u2013present), but we know very little about the bacteriology of pandemics 1 to 5. Moreover, although we are learning about the contribution of non-O1 non-pandemic \n \n V. cholerae<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> to cholera dynamics during the current pandemic, we know almost nothing about their role in the past. A recent ancient DNA study has presented what may be the first molecular evidence of a \n \n V. cholerae<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> infection from the fifth cholera pandemic period (1886\u20131887 AD) in Argentina. Here, we place the molecular evidence from that study into the genomic context of non-pandemic \n \n V. cholerae<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> from Latin America and elsewhere, and show that a gene fragment amplified from ancient DNA is most similar to that of \n \n V. cholerae<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> from the Americas, and from Argentina. Our results corroborate and reinforce the findings of the original study, and collectively suggest that even in the 1880s, non-pandemic \n \n V. cholerae<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> local to the Americas may have caused sporadic infections in Argentina, just as we know this to have happened during the seventh pandemic in Latin America.<\/jats:p>","DOI":"10.1099\/mgen.0.000580","type":"journal-article","created":{"date-parts":[[2021,6,15]],"date-time":"2021-06-15T17:15:42Z","timestamp":1623777342000},"source":"Crossref","is-referenced-by-count":0,"title":["Genomic contextualisation of ancient DNA molecular data from an Argentinian fifth pandemic Vibrio cholerae infection"],"prefix":"10.1099","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7064-6163","authenticated-orcid":false,"given":"Matthew J.","family":"Dorman","sequence":"first","affiliation":[{"name":"Churchill College, Storey\u2019s Way, Cambridge, CB3 0DS, UK"},{"name":"Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, CB10 1SA, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4432-8505","authenticated-orcid":false,"given":"Nicholas R.","family":"Thomson","sequence":"additional","affiliation":[{"name":"London School of Hygiene and Tropical Medicine, Keppel St., Bloomsbury, London, WC1E 7HT, UK"},{"name":"Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, CB10 1SA, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1409-0441","authenticated-orcid":false,"given":"Josefina","family":"Campos","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Enfermedades Infecciosas, INEI-ANLIS \u201cDr. Carlos G. Malbr\u00e1n\u201d, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-18647-7"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpp.2020.12.004"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.6084\/m9.figshare.11310131"},{"year":"1959","key":"R4","article-title":"World Health Organization. Cholera. World Health Organization"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1038\/239137a0"},{"key":"R6","first-page":"10","article-title":"Historical background of cholera in the Americas","volume":"12","author":"Llopis","year":"1991","journal-title":"Epidemiol Bull"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02736-06"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1207359109"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1128\/JB.187.9.2992-3001.2005"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1308663"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1126\/science.aao2136"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.001298"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(05)80360-2"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1038\/35020000"},{"key":"R15","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msp259"},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1093\/sysbio\/syq010"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw290"}],"container-title":["Microbial Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/mgen\/10.1099\/mgen.0.000580?crawler=true&mimetype=application\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T01:24:08Z","timestamp":1702603448000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/mgen\/10.1099\/mgen.0.000580"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,24]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,3,24]]}},"URL":"https:\/\/doi.org\/10.1099\/mgen.0.000580","relation":{},"ISSN":["2057-5858"],"issn-type":[{"type":"electronic","value":"2057-5858"}],"subject":[],"published":{"date-parts":[[2021,3,24]]}}}