{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T07:10:08Z","timestamp":1790493008957,"version":"4.1.0"},"reference-count":33,"publisher":"Microbiology Society","issue":"8","license":[{"start":{"date-parts":[[2022,8,23]],"date-time":"2022-08-23T00:00:00Z","timestamp":1661212800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,23]]},"abstract":"<jats:p>Approximately 200 O-serogroups of <jats:italic>\n                     <jats:named-content content-type=\"species\">\n                        <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/doi.org\/10.1601\/nm.2947\" xlink:type=\"simple\">Vibrio cholerae<\/jats:ext-link>\n                     <\/jats:named-content>\n                  <\/jats:italic> have already been identified; however, only 2 serogroups, O1 and O139, are strongly related to pandemic cholera. The study of non-O1 and non-O139 strains has hitherto been limited. Nevertheless, there are other clinically and epidemiologically important serogroups causing outbreaks with cholera-like disease. Here, we report a comprehensive genome analysis of the whole set of <jats:italic>\n                     <jats:named-content content-type=\"species\">\n                        <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/doi.org\/10.1601\/nm.2947\" xlink:type=\"simple\">V. cholerae<\/jats:ext-link>\n                     <\/jats:named-content>\n                  <\/jats:italic> O-serogroup reference strains to provide an overview of this important bacterial pathogen. It revealed structural diversity of the O-antigen biosynthesis gene clusters located at specific loci on chromosome 1 and 16 pairs of strains with almost identical O-antigen biosynthetic gene clusters but differing in serological patterns. This might be due to the presence of O-antigen biosynthesis-related genes at secondary loci on chromosome 2.<\/jats:p>","DOI":"10.1099\/mgen.0.000860","type":"journal-article","created":{"date-parts":[[2022,8,5]],"date-time":"2022-08-05T15:16:42Z","timestamp":1659712602000},"source":"Crossref","is-referenced-by-count":12,"title":["Genomic dissection of the Vibrio cholerae O-serogroup global reference strains: reassessing our view of diversity and plasticity between two chromosomes"],"prefix":"10.1099","volume":"8","author":[{"given":"Kazunori","family":"Murase","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan"},{"name":"Department of Microbiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiji","family":"Arakawa","sequence":"additional","affiliation":[{"name":"Department of Bacteriology I, National Institute of 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