{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T14:17:47Z","timestamp":1790950667216,"version":"4.1.0"},"reference-count":109,"publisher":"Microbiology Society","issue":"5","license":[{"start":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T00:00:00Z","timestamp":1684972800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000691","name":"Academy of Medical Sciences","doi-asserted-by":"crossref","award":["GCRFNG100309"],"award-info":[{"award-number":["GCRFNG100309"]}],"id":[{"id":"10.13039\/501100000691","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100005363","name":"Universidad de Buenos Aires","doi-asserted-by":"crossref","award":["UBACYT 2018-2020-20020170100665BA"],"award-info":[{"award-number":["UBACYT 2018-2020-20020170100665BA"]}],"id":[{"id":"10.13039\/501100005363","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100002923","name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","doi-asserted-by":"crossref","award":["PIP 2015 11220150100694CO"],"award-info":[{"award-number":["PIP 2015 11220150100694CO"]}],"id":[{"id":"10.13039\/501100002923","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003074","name":"Agencia Nacional de Promoci\u00f3n Cient\u00edfica y Tecnol\u00f3gica","doi-asserted-by":"crossref","award":["Pr\u00e9stamo BID PICT-2016-1726 and PICT2020-03132"],"award-info":[{"award-number":["Pr\u00e9stamo BID PICT-2016-1726 and PICT2020-03132"]}],"id":[{"id":"10.13039\/501100003074","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003074","name":"Agencia Nacional de Promoci\u00f3n Cient\u00edfica y Tecnol\u00f3gica","doi-asserted-by":"crossref","award":["Pr\u00e9stamo BID PICT-2018-03068"],"award-info":[{"award-number":["Pr\u00e9stamo BID PICT-2018-03068"]}],"id":[{"id":"10.13039\/501100003074","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"crossref","award":["Global Health Research Unit on genomic Surveillance of AMR (16_136_111)"],"award-info":[{"award-number":["Global Health Research Unit on genomic Surveillance of AMR (16_136_111)"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,25]]},"abstract":"\n \n \n Staphylococcus aureus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n remains one of the leading causes of infections worldwide and a common cause of bacteraemia. However, studies documenting the epidemiology of\n \n \n S. aureus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n in South America using genomics are scarce. We hereby report on the largest genomic epidemiology study to date of both methicillin-resistant\n \n \n S. aureus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n (MRSA) and methicillin-susceptible\n \n \n S. aureus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n (MSSA) in South America, conducted by the StaphNET-SA network. We characterised 404 genomes recovered from a prospective observational study of\n \n \n S. aureus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n bacteraemia in 58 hospitals from Argentina, Bolivia, Brazil, Paraguay and Uruguay between April and October 2019. We show that a minority of\n \n \n S. aureus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n isolates are phenotypically multi-drug resistant (5.2%), but more than a quarter are resistant to macrolide\u2013lincosamide\u2013streptogramin B (MLSb). MSSA were more genetically diverse than MRSA. Lower rates of associated antimicrobial resistance in community-associated(CA)-MRSA versus hospital-associated (HA)-MRSA were found in association with three\n \n \n S. aureus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n genotypes dominating the MRSA population: CC30-MRSA-IVc-\n t019-lukS\/F-PV+<\/jats:italic>\n , CC5-MRSA-IV-\n t002-lukS\/F-PV-<\/jats:italic>\n and CC8-MRSA-IVc-\n t008-lukS\/F-PV+<\/jats:italic>\n -COMER+. These are historically from a CA origin, carry on average fewer antimicrobial resistance determinants, and often lack key virulence genes. Surprisingly, CC398-MSSA-\n t1451-lukS\/F-PV-<\/jats:italic>\n related to the CC398 human-associated lineage is widely disseminated throughout the region, and is described here for the first time as the most prevalent MSSA lineage in South America. Moreover, CC398 strains carrying\n ermT<\/jats:italic>\n (largely responsible for the MLSb resistance rates of MSSA strains: inducible iMLSb phenotype) and\n sh_fabI<\/jats:italic>\n (related to triclosan resistance) were recovered from both CA and HA origin. The frequency of MRSA and MSSA lineages differed between countries but the most prevalent\n \n \n S. aureus<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>\n genotypes are high-risk clones widely distributed in the South American region without a clear country-specific phylogeographical structure. Therefore, our findings underline the need for continuous genomic surveillance by regional networks such as StaphNET-SA. This article contains data hosted by Microreact.\n <\/jats:p>","DOI":"10.1099\/mgen.0.001020","type":"journal-article","created":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T10:17:59Z","timestamp":1685009879000},"source":"Crossref","is-referenced-by-count":16,"title":["Genomic epidemiology of Staphylococcus aureus isolated from bloodstream infections in South America during 2019 supports regional surveillance"],"prefix":"10.1099","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3787-3318","authenticated-orcid":false,"given":"Sabrina","family":"Di Gregorio","sequence":"first","affiliation":[{"name":"Instituto de Investigaciones en Bacteriolog\u00eda y Virolog\u00eda Molecular (IBaViM), Facultad de Farmacia y Bioqu\u00edmica, Universidad de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas","family":"Vielma","sequence":"additional","affiliation":[{"name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas (CONICET), Ciudad Aut\u00f3noma de Buenos Aires, Argentina"},{"name":"Instituto de Investigaciones en Bacteriolog\u00eda y Virolog\u00eda Molecular (IBaViM), Facultad de Farmacia y Bioqu\u00edmica, Universidad de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0118-1996","authenticated-orcid":false,"given":"Mar\u00eda Sol","family":"Haim","sequence":"additional","affiliation":[{"name":"Unidad Operativa Centro Nacional de Gen\u00f3mica y Bioinform\u00e1tica, ANLIS Dr. Carlos G. Malbr\u00e1n, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"},{"name":"Instituto de Investigaciones en Bacteriolog\u00eda y Virolog\u00eda Molecular (IBaViM), Facultad de Farmacia y Bioqu\u00edmica, Universidad de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc\u00eda","family":"Rago","sequence":"additional","affiliation":[{"name":"Instituto de Investigaciones en Bacteriolog\u00eda y Virolog\u00eda Molecular (IBaViM), Facultad de Farmacia y Bioqu\u00edmica, Universidad de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1409-0441","authenticated-orcid":false,"given":"Josefina","family":"Campos","sequence":"additional","affiliation":[{"name":"Unidad Operativa Centro Nacional de Gen\u00f3mica y Bioinform\u00e1tica, ANLIS Dr. Carlos G. Malbr\u00e1n, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihir","family":"Kekre","sequence":"additional","affiliation":[{"name":"Present address: Tropic Biosciences Ltd, Norwich Research Park, Norwich, UK"},{"name":"Centre for Genomic Pathogen Surveillance, Big Data Institute, University of Oxford, Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0228-4353","authenticated-orcid":false,"given":"Monica","family":"Abrudan","sequence":"additional","affiliation":[{"name":"Centre for Genomic Pathogen Surveillance, Big Data Institute, University of Oxford, Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1ngela","family":"Famiglietti","sequence":"additional","affiliation":[{"name":"Laboratorio de Bacteriolog\u00eda Cl\u00ednica, Hospital de Cl\u00ednicas Jos\u00e9 de San Mart\u00edn, Facultad de Farmacia y Bioqu\u00edmica, Universidad de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6416-7788","authenticated-orcid":false,"given":"Liliana Fernandez","family":"Canigia","sequence":"additional","affiliation":[{"name":"Hospital Alem\u00e1n, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Rubinstein","sequence":"additional","affiliation":[{"name":"Hospital Privado Regional del Sur, Bariloche, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3066-9157","authenticated-orcid":false,"given":"Martha","family":"Helena von Specht","sequence":"additional","affiliation":[{"name":"C\u00e1tedra de Microbiolog\u00eda, Facultad de Ciencias Exactas, Qu\u00edmicas y Naturales, Universidad Nacional de Misiones, Posadas, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4712-2342","authenticated-orcid":false,"given":"Melina","family":"Herrera","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias de la Salud, Universidad Adventista del Plata, Entre R\u00edos, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Aro","sequence":"additional","affiliation":[{"name":"Hospital de Ni\u00f1os Dr. Orlando Alassia, Santa F\u00e9, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo","family":"Galas","sequence":"additional","affiliation":[{"name":"Pan American Health Organization, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norah Balderrama","family":"Yarhui","sequence":"additional","affiliation":[{"name":"Hospital del Ni\u00f1o Manuen Ascencio Villarroel, Cochabamba, Bolivia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8229-6957","authenticated-orcid":false,"given":"Agnes","family":"Figueiredo","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Patologia, Faculdade de Medicina, Universidade Federal Fluminense, Niter\u00f3i, Brazil"},{"name":"Instituto de Microbiologia Paulo de G\u00f3es, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0161-5800","authenticated-orcid":false,"given":"Nilton","family":"Lincopan","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Sciences, Department of Microbiology, Universidade de S\u00e3o Paulo, Sao Pablo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miryan","family":"Falcon","sequence":"additional","affiliation":[{"name":"Present address: Ministerio de Salud P\u00fablica y Bienestar Social, Asunci\u00f3n, Paraguay"},{"name":"Dpto. Bacteriolog\u00eda y Micolog\u00eda, Secci\u00f3n Antimicrobianos, Laboratorio Central de Salud P\u00fablica, Asunci\u00f3n, Paraguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4778-4960","authenticated-orcid":false,"given":"Rosa","family":"Guill\u00e9n","sequence":"additional","affiliation":[{"name":"Instituto de Investigaciones en Ciencias de la Salud, Facultad de Ciencias Qu\u00edmicas, Universidad Nacional de Asunci\u00f3n, Asunci\u00f3n, Paraguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9304-5683","authenticated-orcid":false,"given":"Teresa","family":"Camou","sequence":"additional","affiliation":[{"name":"Unidad de Bacteriolog\u00eda, Departamento de Laboratorios de Salud P\u00fablica, Ministerio de Salud P\u00fablica, Montevideo, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4354-0608","authenticated-orcid":false,"given":"Gustavo","family":"Varela","sequence":"additional","affiliation":[{"name":"C\u00e1tedra de Bacteriolog\u00eda y Virolog\u00eda, Facultad de Medicina, Universidad de la Rep\u00fablica, Montevideo, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6688-0854","authenticated-orcid":false,"given":"David M.","family":"Aanensen","sequence":"additional","affiliation":[{"name":"Centre for Genomic Pathogen Surveillance, Big Data Institute, University of Oxford, Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2884-3857","authenticated-orcid":false,"given":"Silvia","family":"Argim\u00f3n","sequence":"additional","affiliation":[{"name":"Centre for Genomic Pathogen Surveillance, Big Data Institute, University of Oxford, Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5735-8471","authenticated-orcid":false,"given":"Marta","family":"Mollerach","sequence":"additional","affiliation":[{"name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas (CONICET), Ciudad Aut\u00f3noma de Buenos Aires, Argentina"},{"name":"Instituto de Investigaciones en Bacteriolog\u00eda y Virolog\u00eda Molecular (IBaViM), Facultad de Farmacia y Bioqu\u00edmica, Universidad de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of StaphNET-SA consortium","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","article-title":"Antimicrobial resistance. Global report on surveillance"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02724-0"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-018-0147-4"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgar.2016.04.004"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aak9745"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00444-16"},{"key":"R7","article-title":"Magnitud y tendencias de la resistencia a los antimicrobianos en latinoam\u00e9rica. RELAVRA 2014, 2015, 2016","year":"2020"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00816-17"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.3201\/eid2711.210097"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiv320"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6809e1"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz323"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2021.26.46.2002094"},{"key":"R14","article-title":"GLASS whole-genome sequencing for surveillance of antimicrobial resistance","year":"2020"},{"key":"R15","doi-asserted-by":"publisher","DOI":"10.1128\/mSphere.01297-20"},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000215"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES2014.19.49.20987"},{"key":"R18","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing. 29th edition"},{"key":"R19","article-title":"Global antimicrobial resistance surveillance system (GLASS) report: early implementation 2016-2017"},{"key":"R20","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.4702.1"},{"key":"R21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03570.x"},{"key":"R22","article-title":"GHRU (Genomic Surveillance of Antimicrobial Resistance) Retrospective 1 Bioinformatics Methods. protocols.io","author":"Underwood","year":"2020"},{"key":"R23","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00165-06"},{"key":"R24","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000131"},{"key":"R25","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.5261"},{"key":"R26","doi-asserted-by":"publisher","DOI":"10.1128\/mSphere.00612-17"},{"key":"R27","article-title":"Bacterial antimicrobial resistance reference gene. (ID 313047) - BioProject - NCBI"},{"key":"R28","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkx217"},{"key":"R29","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gki008"},{"key":"R30","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02412-14"},{"key":"R31","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu153"},{"key":"R32","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-020-02090-4"},{"key":"R33","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000056"},{"key":"R34","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu033"},{"key":"R35","article-title":"pairsnp","author":"Tonkin-Hill","year":"2022"},{"key":"R36","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0163962"},{"key":"R37","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bts187"},{"key":"R38","article-title":"remove_blocks_from_aln","year":"2021"},{"key":"R39","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku1196"},{"key":"R40","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msu300"},{"key":"R41","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.4285"},{"key":"R42","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msx281"},{"key":"R43","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000093"},{"key":"R44","article-title":"R: A language and environment for statistical computing","year":"2022"},{"key":"R45","doi-asserted-by":"publisher","DOI":"10.5281\/ZENODO.1480624"},{"key":"R46","doi-asserted-by":"publisher","DOI":"10.1111\/2041-210X.12613"},{"key":"R47","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2014.08.002"},{"key":"R48","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2012.12.018"},{"key":"R49","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.12108"},{"key":"R50","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/109.3.211"},{"key":"R51","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/48.1.143"},{"key":"R52","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)85051-4"},{"key":"R53","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1111084108"},{"key":"R54","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.01901"},{"key":"R55","doi-asserted-by":"publisher","DOI":"10.1590\/s1413-86702010000800004"},{"key":"R56","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00040-07"},{"key":"R57","doi-asserted-by":"publisher","DOI":"10.1017\/S095026881100210X"},{"key":"R58","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjid.2019.04.005"},{"key":"R59","doi-asserted-by":"publisher","DOI":"10.1128\/mSphere.00464-17"},{"key":"R60","doi-asserted-by":"publisher","DOI":"10.1128\/mSphere.00571-17"},{"key":"R61","doi-asserted-by":"publisher","DOI":"10.3390\/genes12111752"},{"key":"R62","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms8111737"},{"key":"R63","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01777-14"},{"key":"R64","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01375-16"},{"key":"R65","doi-asserted-by":"crossref","first-page":"e00027","DOI":"10.1128\/mBio.00027-12","article-title":"Identification of a highly transmissible animal-independent Staphylococcus aureus ST398 clone with distinct genomic and cell adhesion properties","volume":"3","author":"Uhlemann","year":"2012","journal-title":"mBio"},{"key":"R66","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-018-3205-y"},{"key":"R67","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks411"},{"key":"R68","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkr348"},{"key":"R69","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01008"},{"key":"R70","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00355-19"},{"key":"R71","article-title":"PAHO\/WHO data - 3. resistance percentages for selected pathogens | PAHO\/WHO","author":"Guti\u00e9rrez","year":"2015","journal-title":"Pan American Health Organization \/ World Health Organization"},{"key":"R72","volume-title":"Programa Nacional de Vigilancia de la Resistencia a los Antimicrobianos, WHONET","volume":"1","author":"Menocal","year":"2022."},{"key":"R73","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0034768"},{"key":"R74","doi-asserted-by":"publisher","DOI":"10.18683\/germs.2020.1191"},{"key":"R75","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2010.10.004"},{"key":"R76","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-020-05127-w"},{"key":"R77","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0072811"},{"key":"R78","doi-asserted-by":"publisher","DOI":"10.1086\/655901"},{"key":"R79","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2014.12.006"},{"key":"R80","doi-asserted-by":"publisher","DOI":"10.1590\/0074-02760170040"},{"key":"R81","doi-asserted-by":"publisher","DOI":"10.3201\/eid1710.110638"},{"key":"R82","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjid.2016.08.006"},{"key":"R83","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofy123"},{"key":"R84","first-page":"585","article-title":"Grupo de estudio de infecciones por staphylococcus aureus de la comunidad - sociedad argentina de infectolog\u00eda (SADI). [community-associated methicillin-resistant Staphylococcus aureus: the emergency of a pathogen]","volume":"71","author":"L\u00f3pez Furst","year":"2011","journal-title":"Medicina"},{"key":"R85","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.2261"},{"key":"R86","article-title":"MERCOSUR RES GMC No 35\/20. Reglamento t\u00e9cnico MERCOSUR sobre lista de sustancias de acci\u00f3N conservadora permitidas para productos de higiene personal, cosm\u00e9ticos y perfumes (derogaci\u00f3N de la resoluci\u00f3N GMC No 07\/11)","year":"2020"},{"key":"R87","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02511-19"},{"key":"R88","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01938-20"},{"key":"R89","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0078303"},{"key":"R90","doi-asserted-by":"publisher","DOI":"10.1080\/21505594.2020.1869484"},{"key":"R91","doi-asserted-by":"publisher","DOI":"10.1155\/2009\/472126"},{"key":"R92","doi-asserted-by":"publisher","DOI":"10.3201\/eid1106.041059"},{"key":"R93","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.4.1985-1988.2005"},{"key":"R94","doi-asserted-by":"publisher","DOI":"10.1128\/JB.187.10.3455-3464.2005"},{"key":"R95","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2013.04.009"},{"key":"R96","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.5.2827-2838.2003"},{"key":"R97","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiv489"},{"key":"R98","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkac154"},{"key":"R99","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2018.12.002"},{"key":"R100","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.000735"},{"key":"R101","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofz360.625"},{"key":"R102","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2013.04.024"},{"key":"R103","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics11091217"},{"key":"R104","doi-asserted-by":"publisher","DOI":"10.2217\/fmb.10.147"},{"key":"R105","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1520255113"},{"key":"R106","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2016.07.003"},{"key":"R107","doi-asserted-by":"publisher","DOI":"10.1080\/21505594.2021.1899616"},{"key":"R108","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.77195"},{"key":"R109","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)02185-7"}],"container-title":["Microbial Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/mgen\/10.1099\/mgen.0.001020?crawler=true&mimetype=application\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T10:18:17Z","timestamp":1685009897000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/mgen\/10.1099\/mgen.0.001020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,25]]},"references-count":109,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5,25]]}},"URL":"https:\/\/doi.org\/10.1099\/mgen.0.001020","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2022.12.20.22283725","asserted-by":"object"}]},"ISSN":["2057-5858"],"issn-type":[{"value":"2057-5858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,25]]}}}