{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T05:26:17Z","timestamp":1740633977327,"version":"3.38.0"},"reference-count":33,"publisher":"Microbiology Society","issue":"2","license":[{"start":{"date-parts":[[2025,2,26]],"date-time":"2025-02-26T00:00:00Z","timestamp":1740528000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100015060","name":"Nagasaki University","doi-asserted-by":"crossref","award":["2021-Ippan-02, 2022-Ippan-06, 2023-Ippan-06"],"award-info":[{"award-number":["2021-Ippan-02, 2022-Ippan-06, 2023-Ippan-06"]}],"id":[{"id":"10.13039\/100015060","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"crossref","award":["JP20wm0125006, JP233fa627004, JP22wm0225023"],"award-info":[{"award-number":["JP20wm0125006, JP233fa627004, JP22wm0225023"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"crossref","award":["JP23fk0108663"],"award-info":[{"award-number":["JP23fk0108663"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,26]]},"abstract":"<jats:p>In 2013, foodborne outbreaks in Japan were linked to non-O1, non-O139 <jats:italic>Vibrio cholerae<\/jats:italic>. However, laboratory tests have detected several serogroups, making it difficult to determine the causative agent. Therefore, whole-genome analyses revealed that only serogroup O144 <jats:italic>V. cholerae<\/jats:italic> possesses a genomic island with a type III secretion system (T3SS). A T3SS-deficient mutant was subsequently generated, and its pathogenicity was assessed using a rabbit ileal loop test. This led to the conclusion that serogroup O144 <jats:italic>V. cholerae<\/jats:italic> with T3SS was the causative agent of foodborne outbreaks. 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