{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T22:18:39Z","timestamp":1781561919332,"version":"3.54.5"},"reference-count":40,"publisher":"Microbiology Society","issue":"9","license":[{"start":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T00:00:00Z","timestamp":1757548800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,11]]},"abstract":"<jats:p>The incidence of gonorrhoea has increased significantly in Norway over the past 10\u2009years. The emergence of antimicrobial resistance and potential for increased rates of future treatment failure make epidemiological surveillance of <jats:italic>Neisseria gonorrhoeae<\/jats:italic> a top priority. Here, we combine epidemiological data and genomic analyses of isolates from cases in Norway between January 2016 and May 2023 to identify genomic clusters and antimicrobial resistance patterns. We describe how the epidemiology of <jats:italic>N. gonorrhoeae<\/jats:italic> has changed before and after the COVID-19 pandemic and the lockdown restrictions of the Norwegian society. A total of 4,096 isolates, representing 39% of all the cases recorded by the Norwegian Surveillance System for Communicable Diseases, were analysed by whole-genome sequencing. Forty-one clusters, 12 of which encompassed more than 100 isolates, were identified. As seen in other countries, the lockdown of society in 2020\u20132021 led to a dramatic reduction in the cases of gonorrhoea. With the lifting of the restrictions, one cluster, dominated by sequence type 1580, rapidly expanded among young, heterosexual men and women. A significant increase in the fraction of female patients was observed through the study period. An increase in isolates resistant to azithromycin was observed throughout the study period, while the proportion of ciprofloxacin and cefixime resistance remained stable. A single ceftriaxone-resistant isolate was identified.<\/jats:p>","DOI":"10.1099\/mgen.0.001479","type":"journal-article","created":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T14:16:20Z","timestamp":1757600180000},"source":"Crossref","is-referenced-by-count":0,"title":["Genome analysis of Neisseria gonorrhoeae in Norway, 2016\u20132023, reveals shifting epidemiology in the wake of the COVID-19 pandemic"],"prefix":"10.1099","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5903-9239","authenticated-orcid":false,"given":"Kristian","family":"Alfsnes","sequence":"first","affiliation":[{"name":"Division for Infection Control, Norwegian Institute of Public Health, 0213 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus N.","family":"Osnes","sequence":"additional","affiliation":[{"name":"Norwegian Veterinary Institute, 1433 \u00c5s, Norway"},{"name":"Division for Infection Control, Norwegian Institute of Public Health, 0213 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanne Margrethe","family":"Gilboe","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Oslo University Hospital, Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vegard","family":"Eldholm","sequence":"additional","affiliation":[{"name":"Division for Infection Control, Norwegian Institute of Public Health, 0213 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique A.","family":"Caugant","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Global Health, Faculty of Medicine, University of Oslo, Blindern, 0316 Oslo, Norway"},{"name":"Division for Infection Control, Norwegian Institute of Public Health, 0213 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","article-title":"Smittevernh\u00e5ndboka - 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