{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T23:07:04Z","timestamp":1786403224092,"version":"build-2736575974"},"reference-count":42,"publisher":"Microbiology Society","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,4,1]]},"DOI":"10.1099\/mic.0.000052","type":"journal-article","created":{"date-parts":[[2015,2,10]],"date-time":"2015-02-10T04:44:57Z","timestamp":1423543497000},"page":"895-902","source":"Crossref","is-referenced-by-count":18,"title":["A single amino acid substitution in the \u03a9-like loop of E. coli PBP5 disrupts its ability to maintain cell shape and intrinsic beta-lactam resistance"],"prefix":"10.1099","volume":"161","author":[{"given":"Mouparna","family":"Dutta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debasish","family":"Kar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankita","family":"Bansal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Chakraborty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anindya S.","family":"Ghosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"r1","doi-asserted-by":"publisher","DOI":"10.1021\/bi972127f"},{"key":"r2","doi-asserted-by":"crossref","first-page":"7106","DOI":"10.1128\/jb.178.24.7106-7111.1996","article-title":"dacD, an Escherichia coli gene encoding a novel penicillin-binding protein (PBP6b) with dd-carboxypeptidase activity","volume":"178","author":"Baquero","year":"1996","journal-title":"J Bacteriol"},{"key":"r3","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0040408"},{"key":"r4","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1042\/bj3010139","article-title":"Kinetics of penicillin binding to penicillin-binding proteins of Staphylococcus aureus","volume":"301","author":"Chambers","year":"1994","journal-title":"Biochem J"},{"key":"r5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2009.01863.x"},{"key":"r6","doi-asserted-by":"publisher","DOI":"10.1111\/1574-6968.12009"},{"key":"r7","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M004471200"},{"key":"r8","doi-asserted-by":"publisher","DOI":"10.1006\/abio.2000.4735"},{"key":"r9","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkl282"},{"key":"r10","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(76)45054-1"},{"key":"r11","doi-asserted-by":"publisher","DOI":"10.1128\/JB.185.7.2178-2186.2003"},{"key":"r12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2006.00429.x"},{"key":"r13","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2008.04.006"},{"key":"r14","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.mi.45.100191.000345"},{"key":"r15","doi-asserted-by":"publisher","DOI":"10.1128\/JB.05764-11"},{"key":"r16","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1128\/MMBR.62.1.181-203.1998","article-title":"Growth of the stress-bearing and shape-maintaining murein sacculus of Escherichia coli","volume":"62","author":"H\u00f6ltje","year":"1998","journal-title":"Microbiol Mol Biol Rev"},{"key":"r17","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1999.3091"},{"key":"r18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1991.tb00739.x"},{"key":"r19","doi-asserted-by":"publisher","DOI":"10.1107\/S0021889892009944"},{"key":"r20","doi-asserted-by":"publisher","DOI":"10.1021\/ja01318a036"},{"key":"r21","doi-asserted-by":"publisher","DOI":"10.1002\/prot.23188"},{"key":"r22","doi-asserted-by":"publisher","DOI":"10.1038\/356083a0"},{"key":"r23","doi-asserted-by":"crossref","first-page":"11386","DOI":"10.1016\/S0021-9258(19)49922-5","article-title":"Substitution of lysine 213 with arginine in penicillin-binding protein 5 of Escherichia coli abolishes d-alanine carboxypeptidase activity without affecting penicillin binding","volume":"267","author":"Malhotra","year":"1992","journal-title":"J Biol Chem"},{"key":"r24","doi-asserted-by":"publisher","DOI":"10.1128\/JB.182.6.1714-1721.2000"},{"key":"r25","doi-asserted-by":"publisher","DOI":"10.1128\/JB.183.10.3055-3064.2001"},{"key":"r26","doi-asserted-by":"publisher","DOI":"10.1128\/JB.184.13.3630-3639.2002"},{"key":"r27","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M310177200"},{"key":"r28","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20050449"},{"key":"r29","doi-asserted-by":"publisher","DOI":"10.1021\/bi0473004"},{"key":"r30","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2004.04050.x"},{"key":"r31","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2010.07205.x"},{"key":"r32","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkh377"},{"key":"r33","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1993.1626"},{"key":"r34","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2009.11.004"},{"key":"r35","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.046227-0"},{"key":"r36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2008.06.012"},{"key":"r37","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-4838(02)00311-4"},{"key":"r38","doi-asserted-by":"publisher","DOI":"10.1110\/ps.0224303"},{"key":"r39","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M805375200"},{"key":"r40","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1042\/bj3030357","article-title":"Site-directed mutagenesis of proposed active-site residues of penicillin-binding protein 5 from Escherichia coli","volume":"303","author":"van der Linden","year":"1994","journal-title":"Biochem J"},{"key":"r41","doi-asserted-by":"publisher","DOI":"10.1021\/bi700777x"},{"key":"r42","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1128\/AAC.43.5.1124","article-title":"BOCILLIN FL, a sensitive and commercially available reagent for detection of penicillin-binding proteins","volume":"43","author":"Zhao","year":"1999","journal-title":"Antimicrob Agents Chemother"}],"container-title":["Microbiology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T04:07:47Z","timestamp":1651205267000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/micro\/10.1099\/mic.0.000052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,1]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,4,1]]}},"URL":"https:\/\/doi.org\/10.1099\/mic.0.000052","relation":{},"ISSN":["1350-0872","1465-2080"],"issn-type":[{"value":"1350-0872","type":"print"},{"value":"1465-2080","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,1]]}}}