{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T20:06:24Z","timestamp":1794081984803,"version":"4.8.0"},"reference-count":10,"publisher":"Microbiology Society","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,8,1]]},"abstract":"<jats:p>\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    is normally a harmless commensal of human beings, but it can cause superficial infections of the mucosa (oral\/vaginal\u2009thrush) in healthy individuals and (rarely) infections of the skin or nails. It can also become invasive, causing life-threatening systemic and bloodstream infections in immunocompromised hosts, where the mortality rate can be as high as 50\u200a%. It is the most common cause of serious fungal infection and is a common cause of nosocomial infections in hospitals. Some strains have been recognized that are resistant to azoles or echinocandins, which are the first-line antifungals for treatment of\n                    <jats:italic>C. albicans<\/jats:italic>\n                    infections.\n                  <\/jats:p>","DOI":"10.1099\/mic.0.000499","type":"journal-article","created":{"date-parts":[[2017,8,15]],"date-time":"2017-08-15T05:12:29Z","timestamp":1502773949000},"page":"1145-1147","source":"Crossref","is-referenced-by-count":135,"title":["Microbe Profile: Candida albicans: a shape-changing, opportunistic pathogenic fungus of humans"],"prefix":"10.1099","volume":"163","author":[{"given":"Neil A. R.","family":"Gow","sequence":"first","affiliation":[{"name":"The Aberdeen Fungal Group, MRC Centre for Medical Mycology, School of Medicine, Medical Science and Nutrition, Institute of Medical Sciences, University of Aberdeen, Aberdeen AB252ZD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhawna","family":"Yadav","sequence":"additional","affiliation":[{"name":"The Aberdeen Fungal Group, MRC Centre for Medical Mycology, School of Medicine, Medical Science and Nutrition, Institute of Medical Sciences, University of Aberdeen, Aberdeen AB252ZD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro.2016.157"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2014.07.001"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0401648101"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2015.0461"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1038\/nature11865"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1126\/science.289.5477.307"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/23.9.1481"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1514201"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1038\/nri3897"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1038\/nature17625"}],"container-title":["Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/micro\/10.1099\/mic.0.000499?crawler=true","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T11:19:51Z","timestamp":1655810391000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/micro\/10.1099\/mic.0.000499"}},"subtitle":["This article is part of the Microbe Profiles collection."],"short-title":[],"issued":{"date-parts":[[2017,8,1]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,8,1]]}},"URL":"https:\/\/doi.org\/10.1099\/mic.0.000499","relation":{},"ISSN":["1350-0872","1465-2080"],"issn-type":[{"value":"1350-0872","type":"print"},{"value":"1465-2080","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,1]]}}}