{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T18:36:47Z","timestamp":1790793407410,"version":"4.1.0"},"reference-count":65,"publisher":"Microbiology Society","issue":"11","funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["AI120489"],"award-info":[{"award-number":["AI120489"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["AI137283"],"award-info":[{"award-number":["AI137283"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,12,1]]},"abstract":"\n Vibrio cholerae,<\/jats:italic> the aetiological agent of cholera, possesses multiple iron acquisition systems, including those for the transport of siderophores. How these systems benefit \n \n V. cholerae<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> in low-iron, polymicrobial communities in environmental settings or during infection remains poorly understood. Here, we demonstrate that in iron-limiting conditions, co-culture of \n \n V. cholerae<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> with a number of individual siderophore-producing microbes significantly promoted \n \n V. cholerae<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> growth in vitro<\/jats:italic>. We further show that in the host environment with low iron, \n \n V. cholerae<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> colonizes better in adult mice in the presence of the siderophore-producing commensal \n \n Escherichia coli<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic>. Taken together, our results suggest that in aquatic reservoirs or during infection, \n \n V. cholerae<\/jats:ext-link>\n <\/jats:named-content>\n <\/jats:italic> may overcome environmental and host iron restriction by hijacking siderophores from other microbes.<\/jats:p>","DOI":"10.1099\/mic.0.000975","type":"journal-article","created":{"date-parts":[[2020,10,19]],"date-time":"2020-10-19T16:20:33Z","timestamp":1603124433000},"page":"1038-1046","source":"Crossref","is-referenced-by-count":24,"title":["Siderophore piracy enhances Vibrio cholerae environmental survival and pathogenesis"],"prefix":"10.1099","volume":"166","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6670-325X","authenticated-orcid":false,"given":"Hyuntae","family":"Byun","sequence":"first","affiliation":[{"name":"Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9740-6386","authenticated-orcid":false,"given":"I-Ji","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5144-7537","authenticated-orcid":false,"given":"Jiandong","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2144-8675","authenticated-orcid":false,"given":"Jessie","family":"Larios Valencia","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9182-5224","authenticated-orcid":false,"given":"Jay","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.00012-07"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1039\/b906679a"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro1046"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000949"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2013.04.010"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1001\/jama.231.1.39"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60436-X"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2002.tb00605.x"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2015.12.038"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1014640108"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01824-14"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1218039110"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2015.08.007"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1038\/nature13738"},{"key":"R15","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.13524"},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00013-12"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.1126\/science.aap8775"},{"key":"R18","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.00007-19"},{"key":"R19","doi-asserted-by":"publisher","DOI":"10.1128\/JB.150.1.148-155.1982"},{"key":"R20","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(94)90084-1"},{"key":"R21","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00626-06"},{"key":"R22","doi-asserted-by":"publisher","DOI":"10.1128\/JB.176.11.3269-3277.1994"},{"key":"R23","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2001.02683.x"},{"key":"R24","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.56.11.2891-2895.1988"},{"key":"R25","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2001.02273.x"},{"key":"R26","doi-asserted-by":"publisher","DOI":"10.1128\/JB.182.8.2350-2353.2000"},{"key":"R27","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00417-15"},{"key":"R28","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.7.3419-3426.2002"},{"key":"R29","doi-asserted-by":"publisher","DOI":"10.1128\/JB.181.24.7588-7596.1999"},{"key":"R30","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.74.2.1141-1147.2006"},{"key":"R31","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01296-13"},{"key":"R32","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01144-08"},{"key":"R33","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1406478111"},{"key":"R34","doi-asserted-by":"publisher","DOI":"10.1038\/msb4100050"},{"key":"R35","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth895"},{"key":"R36","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00508-13"},{"key":"R37","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.38.5.1011-1014.1979"},{"key":"R38","doi-asserted-by":"publisher","DOI":"10.1128\/JB.147.1.227-235.1981"},{"key":"R39","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01027-10"},{"key":"R40","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0630018100"},{"key":"R41","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.00046-15"},{"key":"R42","doi-asserted-by":"publisher","DOI":"10.1007\/BF00569233"},{"key":"R43","volume-title":"Iron Transport in Bacteria","author":"Payne","year":"2004"},{"key":"R44","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4165(98)00089-0"},{"key":"R45","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0604650103"},{"key":"R46","doi-asserted-by":"publisher","DOI":"10.1007\/s10534-006-9073-4"},{"key":"R47","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0161341"},{"key":"R48","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-6207"},{"key":"R49","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2019.136113"},{"key":"R50","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2019.06.033"},{"key":"R51","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2019.06.038"},{"key":"R52","doi-asserted-by":"publisher","DOI":"10.3390\/nu9090962"},{"key":"R53","doi-asserted-by":"publisher","DOI":"10.1007\/s12185-017-2366-2"},{"key":"R54","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2009.11.008"},{"key":"R55","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2006.03.014"},{"key":"R56","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2002.02885.x"},{"key":"R57","doi-asserted-by":"publisher","DOI":"10.1271\/bbb.120774"},{"key":"R58","doi-asserted-by":"publisher","DOI":"10.1007\/s00284-005-0400-8"},{"key":"R59","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00629-13"},{"key":"R60","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.28139-0"},{"key":"R61","doi-asserted-by":"publisher","DOI":"10.1099\/13500872-142-5-1191"},{"key":"R62","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2014.123"},{"key":"R63","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2012.11.027"},{"key":"R64","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.13049"},{"key":"R65","first-page":"1","article-title":"Bacterial siderophores in community and host interactions","author":"Kramer","year":"2019","journal-title":"Nat Rev Microbiol"}],"container-title":["Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/micro\/10.1099\/mic.0.000975?crawler=true","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,3]],"date-time":"2020-12-03T19:12:43Z","timestamp":1607022763000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/micro\/10.1099\/mic.0.000975"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,1]]},"references-count":65,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,12,1]]}},"URL":"https:\/\/doi.org\/10.1099\/mic.0.000975","relation":{},"ISSN":["1350-0872","1465-2080"],"issn-type":[{"value":"1350-0872","type":"print"},{"value":"1465-2080","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,1]]}}}