{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:18:07Z","timestamp":1791389887826,"version":"4.3.3"},"reference-count":56,"publisher":"Microbiology Society","issue":"4","license":[{"start":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T00:00:00Z","timestamp":1714003200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010387","name":"Universidad de Sonora","doi-asserted-by":"crossref","award":["USO413008356"],"award-info":[{"award-number":["USO413008356"]}],"id":[{"id":"10.13039\/501100010387","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,4,25]]},"abstract":"<jats:p>\n                  <jats:bold>Introduction.<\/jats:bold>\n                  <jats:italic>Leclercia adecarboxylata<\/jats:italic> is a member of Enterobacterales, often considered an opportunistic pathogen. Recent reports have highlighted <jats:italic>L. adecarboxylata<\/jats:italic> as an emerging pathogen harbouring virulence and resistance determinants.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Gap statement.<\/jats:bold> Little information exists on virulence and resistance determinants in <jats:italic>L. adecarboxylata<\/jats:italic> strains isolated from environmental, food, and clinical samples.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Aim.<\/jats:bold> To determine the presence of resistance and virulence determinants and plasmid features in <jats:italic>L. adecarboxylata<\/jats:italic> strains isolated from environmental, food, and clinical samples, as well as their phylogenetic relationship.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Results.<\/jats:bold> All strains tested showed resistance to \u03b2-lactams and quinolones but were sensitive to aminoglycosides and nitrofurans. However, even though fosfomycin resistance is considered a characteristic trait of <jats:italic>L. adecarboxylata<\/jats:italic>, the resistance phenotype was only observed in 50\u200a% of the strains; <jats:italic>bla<\/jats:italic>\n                  <jats:sub>TEM<\/jats:sub> was the most prevalent BLEE gene (70\u200a%), while the quinolone <jats:italic>qnrB<\/jats:italic> gene was observed in 60\u200a% of the strains. Virulence genes were differentially observed in the strains, with adhesion-related genes being the most abundant, followed by toxin genes. Finally, all strains carried one to seven plasmid bands ranging from 7 to 125 kbps and harboured several plasmid addiction systems, such as ParDE, VagCD, and CcdAB in 80\u200a% of the strains.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusions.<\/jats:bold>\n                  <jats:italic>L. adecarboxylata<\/jats:italic> is an important emerging pathogen that may harbour resistance and virulence genes. Additionally, it has mobilizable genetic elements that may contribute to the dissemination of genetic determinants to other bacterial genera.<\/jats:p>","DOI":"10.1099\/mic.0.001457","type":"journal-article","created":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T15:17:33Z","timestamp":1714058253000},"source":"Crossref","is-referenced-by-count":5,"title":["Resistance phenotype and virulence potential of Leclercia adecarboxylata strains isolated from different sources"],"prefix":"10.1099","volume":"170","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9245-1846","authenticated-orcid":false,"given":"Viviana","family":"Yescas-Zazueta","sequence":"first","affiliation":[{"name":"Departamento de Ciencias Qu\u00edmico Biol\u00f3gicas y Agropecuarias, Universidad de Sonora, campus Caborca, Av. Universidad e Irigoyen S\/N, 83621 H. 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